Functions of the FAK family kinases in T cells: beyond actin cytoskeletal rearrangement. - sprookjes - yvandenbroek - TriplyDB

Functions of the FAK family kinases in T cells: beyond actin cytoskeletal rearrangement.

Functions of the FAK family kinases in T cells: beyond actin cytoskeletal rearrangement.

http://www.wikidata.org/entity/Q34016697

about

Pyk2 activates the NLRP3 inflammasome by directly phosphorylating ASC and contributes to inflammasome-dependent peritonitis Dynamin2 controls Rap1 activation and integrin clustering in human T lymphocyte adhesion Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy.Positive and negative regulation by SLP-76/ADAP and Pyk2 of chemokine-stimulated T-lymphocyte adhesion mediated by integrin α4β1 Pyk2 Controls Integrin-Dependent CTL Migration through Regulation of De-Adhesion.Glycerol monolaurate induces filopodia formation by disrupting the association between LAT and SLP-76 microclusters.Endogenous Control Mechanisms of FAK and PYK2 and Their Relevance to Cancer Development.

P2860

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P2860

Functions of the FAK family kinases in T cells: beyond actin cytoskeletal rearrangement.

http://www.wikidata.org/entity/Q34016697

description

2014 nî lūn-bûn

@nan

2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Functions of the FAK family kinases in T cells: beyond actin cytoskeletal rearrangement.

@ast

Functions of the FAK family kinases in T cells: beyond actin cytoskeletal rearrangement.

@en

Functions of the FAK family kinases in T cells: beyond actin cytoskeletal rearrangement.

@nl

type

label

Functions of the FAK family kinases in T cells: beyond actin cytoskeletal rearrangement.

@ast

Functions of the FAK family kinases in T cells: beyond actin cytoskeletal rearrangement.

@en

Functions of the FAK family kinases in T cells: beyond actin cytoskeletal rearrangement.

@nl

prefLabel

Functions of the FAK family kinases in T cells: beyond actin cytoskeletal rearrangement.

@ast

Functions of the FAK family kinases in T cells: beyond actin cytoskeletal rearrangement.

@en

Functions of the FAK family kinases in T cells: beyond actin cytoskeletal rearrangement.

@nl

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Immunologic Research

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Functions of the FAK family kinases in T cells: beyond actin cytoskeletal rearrangement.

@en

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Nicole M Chapman

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P2860

Protein-tyrosine kinase Pyk2 is involved in interleukin-2 production by Jurkat T cells via its tyrosine 402

Activation of a novel calcium-dependent protein-tyrosine kinase. Correlation with c-Jun N-terminal kinase but not mitogen-activated protein kinase activation

A calcium-dependent tyrosine kinase splice variant in human monocytes. Activation by a two-stage process involving adherence and a subsequent intracellular signal

Overexpressed Csk tyrosine kinase is localized in focal adhesions, causes reorganization of alpha v beta 5 integrin, and interferes with HeLa cell spreading

T cell activation

Tyrosine phosphorylation of Pyk2 is selectively regulated by Fyn during TCR signaling

RAFTK, a novel member of the focal adhesion kinase family, is phosphorylated and associates with signaling molecules upon activation of mature T lymphocytes

Structural basis for the interaction between focal adhesion kinase and CD4

Beta 1-integrin-mediated cell signaling in T lymphocytes

Csk homologous kinase associates with RAFTK/Pyk2 in breast cancer cells and negatively regulates its activation and breast cancer cell migration

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23-34

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