Hepatitis C virus translation inhibitors targeting the internal ribosomal entry site. - sprookjes - yvandenbroek - TriplyDB

Hepatitis C virus translation inhibitors targeting the internal ribosomal entry site.

Hepatitis C virus translation inhibitors targeting the internal ribosomal entry site.

http://www.wikidata.org/entity/Q34038589

about

Small molecules targeting viral RNA Exploring Internal Ribosome Entry Sites as Therapeutic Targets Structure based approaches for targeting non-coding RNAs with small molecules Advancing viral RNA structure prediction: measuring the thermodynamics of pyrimidine-rich internal loops Functional analysis of Kaposi's sarcoma-associated herpesvirus vFLIP expression reveals a new mode of IRES-mediated translation.Functional conservation despite structural divergence in ligand-responsive RNA switches.Ligand-responsive RNA mechanical switches.Inhibition of Hepatitis C Virus in Mice by a Small Interfering RNA Targeting a Highly Conserved Sequence in Viral IRES Pseudoknot.A highly conserved G-rich consensus sequence in hepatitis C virus core gene represents a new anti-hepatitis C target.Conformational flexibility of viral RNA switches studied by FRET.Modulation of the E. coli rpoH Temperature Sensor with Triptycene-Based Small Molecules.Translation initiation of the HIV-1 mRNA.The therapeutic potential of new investigational hepatitis C virus translation inhibitors.Dynamics of IRES-mediated translation.Functional RNA structures throughout the Hepatitis C Virus genome.Molecular architecture of the ribosome-bound Hepatitis C Virus internal ribosomal entry site RNA.An accurately preorganized IRES RNA structure enables eIF4G capture for initiation of viral translation.Computational study of the structural plasticity and the ligand binding affinity of the IRES subdomain IIa.Non-coding RNA: Antibiotic tricks a switch.Viral internal ribosomal entry sites: four classes for one goal.Current and future targets of antiviral therapy in the hepatitis C virus life cycle

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P2860

Hepatitis C virus translation inhibitors targeting the internal ribosomal entry site.

http://www.wikidata.org/entity/Q34038589

description

2013 nî lūn-bûn

@nan

2013 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

Hepatitis C virus translation inhibitors targeting the internal ribosomal entry site.

@ast

Hepatitis C virus translation inhibitors targeting the internal ribosomal entry site.

@en

Hepatitis C virus translation inhibitors targeting the internal ribosomal entry site.

@nl

type

label

Hepatitis C virus translation inhibitors targeting the internal ribosomal entry site.

@ast

Hepatitis C virus translation inhibitors targeting the internal ribosomal entry site.

@en

Hepatitis C virus translation inhibitors targeting the internal ribosomal entry site.

@nl

prefLabel

Hepatitis C virus translation inhibitors targeting the internal ribosomal entry site.

@ast

Hepatitis C virus translation inhibitors targeting the internal ribosomal entry site.

@en

Hepatitis C virus translation inhibitors targeting the internal ribosomal entry site.

@nl

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P1433

Journal of Medicinal Chemistry

P1476

Hepatitis C virus translation inhibitors targeting the internal ribosomal entry site

@en

P2093

Emily Garcia Sega

http://www.w3.org/2001/XMLSchema#string

Kejia Ding

http://www.w3.org/2001/XMLSchema#string

Kevin D Rynearson

http://www.w3.org/2001/XMLSchema#string

Maia Carnevali

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Maria P Castaldi

http://www.w3.org/2001/XMLSchema#string

Mark A Boerneke

http://www.w3.org/2001/XMLSchema#string

Nicholas D Brunn

http://www.w3.org/2001/XMLSchema#string

Sergey M Dibrov

http://www.w3.org/2001/XMLSchema#string

Shu Zhou

http://www.w3.org/2001/XMLSchema#string

Thomas Hermann

http://www.w3.org/2001/XMLSchema#string

P2860

The internal ribosome entry site (IRES) of hepatitis C virus visualized by electron microscopy.

Crystal structure of the HCV IRES central domain reveals strategy for start-codon positioning

A hepatitis C virus (HCV) internal ribosome entry site (IRES) domain III-IV-targeted aptamer inhibits translation by binding to an apical loop of domain IIId

Basic local alignment search tool

A small yeast RNA blocks hepatitis C virus internal ribosome entry site (HCV IRES)-mediated translation and inhibits replication of a chimeric poliovirus under translational control of the HCV IRES element.

Sequences in the 5' nontranslated region of hepatitis C virus required for RNA replication.

A peptide derived from RNA recognition motif 2 of human la protein binds to hepatitis C virus internal ribosome entry site, prevents ribosomal assembly, and inhibits internal initiation of translation.

A potential RNA drug target in the hepatitis C virus internal ribosomal entry site.

Mechanism of ribosome recruitment by hepatitis C IRES RNA

Antisense oligonucleotides targeted to the domain IIId of the hepatitis C virus IRES compete with 40S ribosomal subunit binding and prevent in vitro translation

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1694-1707

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scholarly article

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10.1021/JM401312N

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24138284

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