Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice.
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Defects in Germinal Center Selection in SLEThe rationale for BAFF inhibition in systemic lupus erythematosusContribution of Toll-like receptor signaling to germinal center antibody responsesPathogenic Inflammation and Its Therapeutic Targeting in Systemic Lupus ErythematosusBAFF regulates follicular helper t cells and affects their accumulation and interferon-γ production in autoimmunity.Neutrophils contribute to excess serum BAFF levels and promote CD4+ T cell and B cell responses in lupus-prone mice.B cell maturation antigen deficiency exacerbates lymphoproliferation and autoimmunity in murine lupusPathways leading to an immunological disease: systemic lupus erythematosus.The function of BAFF on T helper cells in autoimmunityRequirement for MyD88 signaling in B cells and dendritic cells for germinal center anti-nuclear antibody production in Lyn-deficient miceIncreased levels of BAFF and APRIL related to human active pulmonary tuberculosis.Complement opsonization of HIV-1 results in decreased antiviral and inflammatory responses in immature dendritic cells via CR3Murine models of systemic lupus erythematosusInnate immune programing by endotoxin and its pathological consequencesIFN-γ production by memory helper T cells is required for CD40-independent alloantibody responses.BAFF knockout improves systemic inflammation via regulating adipose tissue distribution in high-fat diet-induced obesity.CD8+ T cells regulate bone tumor burden independent of osteoclast resorption.IFN-α confers resistance of systemic lupus erythematosus nephritis to therapy in NZB/W F1 miceIFN-β treatment requires B cells for efficacy in neuroautoimmunity.Deletion of Syk in neutrophils prevents immune complex arthritisB cell-derived IL-10 suppresses inflammatory disease in Lyn-deficient mice.PRKDC mutations associated with immunodeficiency, granuloma, and autoimmune regulator-dependent autoimmunity.Unbiased modifier screen reveals that signal strength determines the regulatory role murine TLR9 plays in autoantibody production.The B Cell-Stimulatory Cytokines BLyS and APRIL Are Elevated in Human Periodontitis and Are Required for B Cell-Dependent Bone Loss in Experimental Murine Periodontitis.Genetic Interaction between Lyn, Ets1, and Btk in the Control of Antibody Levels.B Cell-Activating Factor. An Orchestrator of Lymphoid Follicles in Severe Chronic Obstructive Pulmonary Disease.Functions of the Lyn tyrosine kinase in health and diseaseLyn deficiency affects B-cell maturation as well as survivalElevated BCR signaling and decreased survival of Lyn-deficient transitional and follicular B cells.B-cell activating factor targeted therapy and lupus.The structural wedge domain of the receptor-like tyrosine phosphatase CD45 enforces B cell tolerance by regulating substrate specificity.Neutrophils in animal models of autoimmune diseaseImmune Defense Protein Expression in Highly Purified Mouse Lung Epithelial Cells.Genetic susceptibility to lupus: the biological basis of genetic risk found in B cell signaling pathways.Hyperactivated MyD88 signaling in dendritic cells, through specific deletion of Lyn kinase, causes severe autoimmunity and inflammationIL-21 promotes the production of anti-DNA IgG but is dispensable for kidney damage in lyn-/- mice.The effect of BAFF inhibition on autoreactive B cell selection in murine SLE.LYN- and AIRE-mediated tolerance checkpoint defects synergize to trigger organ-specific autoimmunity.B cell-specific loss of Lyn kinase leads to autoimmunityPost-transplantation B cell activating factor and B cell recovery before onset of chronic graft-versus-host disease.
P2860
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P2860
Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Myeloid cells, BAFF, and IFN-g ...... mmunity in Lyn-deficient mice.
@ast
Myeloid cells, BAFF, and IFN-g ...... mmunity in Lyn-deficient mice.
@en
Myeloid cells, BAFF, and IFN-g ...... mmunity in Lyn-deficient mice.
@nl
type
label
Myeloid cells, BAFF, and IFN-g ...... mmunity in Lyn-deficient mice.
@ast
Myeloid cells, BAFF, and IFN-g ...... mmunity in Lyn-deficient mice.
@en
Myeloid cells, BAFF, and IFN-g ...... mmunity in Lyn-deficient mice.
@nl
prefLabel
Myeloid cells, BAFF, and IFN-g ...... mmunity in Lyn-deficient mice.
@ast
Myeloid cells, BAFF, and IFN-g ...... mmunity in Lyn-deficient mice.
@en
Myeloid cells, BAFF, and IFN-g ...... mmunity in Lyn-deficient mice.
@nl
P2093
P2860
P356
P1476
Myeloid cells, BAFF, and IFN-g ...... mmunity in Lyn-deficient mice.
@en
P2093
Anthony L Defranco
Ching-Liang Chu
Clifford A Lowell
Marco A Cassatella
Patrizia Scapini
Thi-Sau Migone
Yongmei Hu
P2860
P304
P356
10.1084/JEM.20100086
P407
P577
2010-07-12T00:00:00Z