Regulated nuclear import of the STAT1 transcription factor by direct binding of importin-alpha - sprookjes - yvandenbroek - TriplyDB

Regulated nuclear import of the STAT1 transcription factor by direct binding of importin-alpha

Regulated nuclear import of the STAT1 transcription factor by direct binding of importin-alpha

http://www.wikidata.org/entity/Q34086377

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Principles of interleukin (IL)-6-type cytokine signalling and its regulation A nonconventional nuclear localization signal within the UL84 protein of human cytomegalovirus mediates nuclear import via the importin alpha/beta pathway Transcriptional regulation by STAT1 and STAT2 in the interferon JAK-STAT pathway Inborn errors of human STAT1: allelic heterogeneity governs the diversity of immunological and infectious phenotypes VP8, the Major Tegument Protein of Bovine Herpesvirus 1, Interacts with Cellular STAT1 and Inhibits Interferon Beta Signaling Arginine/lysine-rich nuclear localization signals mediate interactions between dimeric STATs and importin alpha 5 STAT3 nuclear import is independent of tyrosine phosphorylation and mediated by importin-alpha3.PAK-dependent STAT5 serine phosphorylation is required for BCR-ABL-induced leukemogenesis A novel sequence in the coiled-coil domain of Stat3 essential for its nuclear translocation PIPINO: A Software Package to Facilitate the Identification of Protein-Protein Interactions from Affinity Purification Mass Spectrometry Data Stat1 nuclear translocation by nucleolin upon monocyte differentiation.Structural and functional studies of STAT1 from Atlantic salmon (Salmo salar).Ebolavirus VP24 binding to karyopherins is required for inhibition of interferon signaling.Muscovy duck reovirus p10.8 protein localizes to the nucleus via a nonconventional nuclear localization signal Implications of an antiparallel dimeric structure of nonphosphorylated STAT1 for the activation-inactivation cycle.Molecular symbiosis of CHOP and C/EBP beta isoform LIP contributes to endoplasmic reticulum stress-induced apoptosis.Leishmania donovani amastigotes impair gamma interferon-induced STAT1alpha nuclear translocation by blocking the interaction between STAT1alpha and importin-alpha5 Rabies virus P protein interacts with STAT1 and inhibits interferon signal transduction pathways.Ebola virus VP24 targets a unique NLS binding site on karyopherin alpha 5 to selectively compete with nuclear import of phosphorylated STAT1.Two glutamic acid residues in the DNA-binding domain are engaged in the release of STAT1 dimers from DNA.Interferon-stimulated genes: a complex web of host defenses.Molecular Mechanisms of Innate Immune Inhibition by Non-Segmented Negative-Sense RNA Viruses.Ebola virus VP24 binds karyopherin alpha1 and blocks STAT1 nuclear accumulation HDAC4-regulated STAT1 activation mediates platinum resistance in ovarian cancer.STAT1 signaling is not regulated by a phosphorylation-acetylation switch Karyopherins: potential biological elements involved in the delayed graft function in renal transplant recipients.A conserved motif in the linker domain of STAT1 transcription factor is required for both recognition and release from high-affinity DNA-binding sites The ins and outs of STAT1 nuclear transport.DNA binding reduces the dissociation rate of STAT1 dimers and impairs the interdimeric exchange of protomers.Nuclear import of bovine papillomavirus type 1 E1 protein is mediated by multiple alpha importins and is negatively regulated by phosphorylation near a nuclear localization signal.Regulation of karyopherin α1 and nuclear import by mammalian target of rapamycin.Getting the message across, STAT! Design principles of a molecular signaling circuit.DNA binding controls inactivation and nuclear accumulation of the transcription factor Stat1.Deubiquitinase USP2a Sustains Interferons Antiviral Activity by Restricting Ubiquitination of Activated STAT1 in the Nucleus.Rac1 and a GTPase-activating protein, MgcRacGAP, are required for nuclear translocation of STAT transcription factors.The Arginine/Lysine-Rich Element within the DNA-Binding Domain Is Essential for Nuclear Localization and Function of the Intracellular Pathogen Resistance 1 Nucleocytoplasmic shuttling by nucleoporins Nup153 and Nup214 and CRM1-dependent nuclear export control the subcellular distribution of latent Stat1.Tracking STAT nuclear traffic.Recruitment of Stat1 to chromatin is required for interferon-induced serine phosphorylation of Stat1 transactivation domain Involvement of importin-4 in the transport of transition protein 2 into the spermatid nucleus.

P2860

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P2860

Regulated nuclear import of the STAT1 transcription factor by direct binding of importin-alpha

http://www.wikidata.org/entity/Q34086377

description

2002 nî lūn-bûn

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2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի ապրիլին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

Regulated nuclear import of th ...... rect binding of importin-alpha

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Regulated nuclear import of th ...... rect binding of importin-alpha

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Regulated nuclear import of th ...... rect binding of importin-alpha

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type

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Regulated nuclear import of th ...... rect binding of importin-alpha

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Regulated nuclear import of th ...... rect binding of importin-alpha

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Regulated nuclear import of th ...... rect binding of importin-alpha

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Regulated nuclear import of th ...... rect binding of importin-alpha

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Regulated nuclear import of th ...... rect binding of importin-alpha

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Regulated nuclear import of th ...... rect binding of importin-alpha

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P1433

The EMBO Journal

P1476

Regulated nuclear import of th ...... rect binding of importin-alpha

@en

P2093

Christine McDonald

http://www.w3.org/2001/XMLSchema#string

Gregg Banninger

http://www.w3.org/2001/XMLSchema#string

Kevin M McBride

http://www.w3.org/2001/XMLSchema#string

Nancy C Reich

http://www.w3.org/2001/XMLSchema#string

P2860

T RANSPORT B ETWEEN THE C ELL N UCLEUS AND THE C YTOPLASM

Nucleocytoplasmic translocation of Stat1 is regulated by a leucine-rich export signal in the coiled-coil domain

Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins

Export of importin alpha from the nucleus is mediated by a specific nuclear transport factor

RAG-1 interacts with the repeated amino acid motif of the human homologue of the yeast protein SRP1

Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA

Regulated nuclear-cytoplasmic localization of interferon regulatory factor 3, a subunit of double-stranded RNA-activated factor 1

Evidence for distinct substrate specificities of importin alpha family members in nuclear protein import

The conserved amino-terminal domain of hSRP1 alpha is essential for nuclear protein import

A 41 amino acid motif in importin-alpha confers binding to importin-beta and hence transit into the nucleus

P304

1754-1763

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scholarly article

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10.1093/EMBOJ/21.7.1754

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P407

P433

7

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P478

21

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2002-04-01T00:00:00Z

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11437019

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P698

11927559

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P932

125956

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