ATF3 represses 72-kDa type IV collagenase (MMP-2) expression by antagonizing p53-dependent trans-activation of the collagenase promoter.
about
The human solute carrier family 11 member 1 protein (SLC11A1): linking infections, autoimmunity and cancer?Activation of the canonical Wnt/β-catenin pathway in ATF3-induced mammary tumorsThe transcription factor ATF3 acts as an oncogene in mouse mammary tumorigenesisInhibition of the proprotein convertases represses the invasiveness of human primary melanoma cells with altered p53, CDKN2A and N-Ras genes.Trimming of mammalian transcriptional networks using network component analysis.Activating transcription factor 3 activates p53 by preventing E6-associated protein from binding to E6.NS-398, ibuprofen, and cyclooxygenase-2 RNA interference produce significantly different gene expression profiles in prostate cancer cells.Dynamic expression patterns of ATF3 and p53 in the hippocampus of a pentylenetetrazole-induced kindling model.MDM2 mediates ubiquitination and degradation of activating transcription factor 3Transcriptional repressor activating transcription factor 3 protects human umbilical vein endothelial cells from tumor necrosis factor-alpha-induced apoptosis through down-regulation of p53 transcription.ATF3 induction following DNA damage is regulated by distinct signaling pathways and over-expression of ATF3 protein suppresses cells growth.Resveratrol-induced apoptosis is mediated by early growth response-1, Krüppel-like factor 4, and activating transcription factor 3.ATF3 functions as a novel tumor suppressor with prognostic significance in esophageal squamous cell carcinoma.The dietary compounds resveratrol and genistein induce activating transcription factor 3 while suppressing inhibitor of DNA binding/differentiation-1.A small-molecule p53 activator induces apoptosis through inhibiting MDMX expression in breast cancer cells.Activating transcription factor 3 is overexpressed in human glioma and its knockdown in glioblastoma cells causes growth inhibition both in vitro and in vivo.Loss of ATF3 promotes Akt activation and prostate cancer development in a Pten knockout mouse modelThe role of matrix degrading enzymes and apoptosis in rupture of membranes.Induction of activating transcription factor 3 limits survival following infarct-induced heart failure in mice.3', 5'-cyclic adenosine 5'-monophosphate response element-dependent transcriptional regulation of the secretogranin II gene promoter depends on gonadotropin-releasing hormone-induced mitogen-activated protein kinase activation and the transactivatorThe initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin.COX inhibitors directly alter gene expression: role in cancer prevention?Clinicopathological and prognostic significance of Ki-67, caspase-3 and p53 expression in gastric carcinomas.Age-related brain expression and regulation of the chemokine CCL4/MIP-1β in APP/PS1 double-transgenic mice.The activating transcription factor 3 protein suppresses the oncogenic function of mutant p53 proteins.The anticancer effects of resveratrol: modulation of transcription factors.Histone H3 acetylation and H3 K4 methylation define distinct chromatin regions permissive for transgene expression.A small-molecule inhibitor of MDMX activates p53 and induces apoptosis.Alterations of metastasis-related genes identified using an oligonucleotide microarray of genistein-treated HCC1395 breast cancer cells.DNA damage in transcribed genes induces apoptosis via the JNK pathway and the JNK-phosphatase MKP-1.Oxidative stress-responsive transcription factor ATF3 potentially mediates diabetic angiopathy.Combination of MEK and SRC inhibition suppresses melanoma cell growth and invasion.Repression of 92-kDa type IV collagenase expression by MTA1 is mediated through direct interactions with the promoter via a mechanism, which is both dependent on and independent of histone deacetylation.Regulation of proglucagon transcription by activated transcription factor (ATF) 3 and a novel isoform, ATF3b, through the cAMP-response element/ATF site of the proglucagon gene promoter.Activating transcription factor 3, a stress-inducible gene, suppresses Ras-stimulated tumorigenesis.Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis.TGF-β-Induced Quiescence Mediates Chemoresistance of Tumor-Propagating Cells in Squamous Cell Carcinoma.Atf3 deficiency promotes genome instability and spontaneous tumorigenesis in mice.Nitric oxide and p38 MAP kinase mediate shear stress-dependent inhibition of MMP-2 production in microvascular endothelial cells.
P2860
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P2860
ATF3 represses 72-kDa type IV collagenase (MMP-2) expression by antagonizing p53-dependent trans-activation of the collagenase promoter.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
ATF3 represses 72-kDa type IV ...... n of the collagenase promoter.
@ast
ATF3 represses 72-kDa type IV ...... n of the collagenase promoter.
@en
ATF3 represses 72-kDa type IV collagenase
@nl
type
label
ATF3 represses 72-kDa type IV ...... n of the collagenase promoter.
@ast
ATF3 represses 72-kDa type IV ...... n of the collagenase promoter.
@en
ATF3 represses 72-kDa type IV collagenase
@nl
prefLabel
ATF3 represses 72-kDa type IV ...... n of the collagenase promoter.
@ast
ATF3 represses 72-kDa type IV ...... n of the collagenase promoter.
@en
ATF3 represses 72-kDa type IV collagenase
@nl
P2093
P2860
P356
P1476
ATF3 represses 72-kDa type IV ...... n of the collagenase promoter.
@en
P2093
Chunhong Yan
Douglas D Boyd
P2860
P304
10804-10812
P356
10.1074/JBC.M112069200
P407
P577
2002-01-15T00:00:00Z