What made sesquiterpene lactones reach cancer clinical trials?
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Sesquiterpene Lactones from Artemisia Genus: Biological Activities and Methods of Analysis3,6-Epidioxy-1,10-bisaboladiene inhibits G1 -specific transcription through Swi4/Swi6 and Mbp1/Swi6 via the Hog1 stress pathway in yeast.Parthenolide-Induced Cytotoxicity in H9c2 Cardiomyoblasts Involves Oxidative StressIsoalantolactone inhibits UM-SCC-10A cell growth via cell cycle arrest and apoptosis inductionEconomically viable components from Jerusalem artichoke (Helianthus tuberosus L.) in a biorefinery conceptSesquiterpene lactone containing extracts from two cultivars of forage chicory (Cichorium intybus) show distinctive chemical profiles and in vitro activity against Ostertagia ostertagiCovalent Modifiers: A Chemical Perspective on the Reactivity of α,β-Unsaturated Carbonyls with Thiols via Hetero-Michael Addition ReactionsTomentosin Induces Telomere Shortening and Caspase-Dependant Apoptosis in Cervical Cancer Cells.(-)-Xanthatin up-regulation of the GADD45γ tumor suppressor gene in MDA-MB-231 breast cancer cells: role of topoisomerase IIα inhibition and reactive oxygen speciesApoptosis induction by 13-acetoxyrolandrolide through the mitochondrial intrinsic pathway.MCL Plays an Anti-Inflammatory Role in Mycobacterium tuberculosis-Induced Immune Response by Inhibiting NF-κB and NLRP3 Inflammasome Activation.NOTCH inhibits osteoblast formation in inflammatory arthritis via noncanonical NF-κB.Selective cytotoxicity, inhibition of cell cycle progression, and induction of apoptosis in human breast cancer cells by sesquiterpenoids from Inula lineariifolia Turcz.Expanding the Antimalarial Drug Arsenal-Now, But How?Xanthatin induces cell cycle arrest at G2/M checkpoint and apoptosis via disrupting NF-κB pathway in A549 non-small-cell lung cancer cells.Sesquiterpene lactones isolated from indigenous Middle Eastern plants inhibit tumor promoter-induced transformation of JB6 cells.The sesquiterpene lactone dehydroleucodine triggers senescence and apoptosis in association with accumulation of DNA damage markers.NF-κB signaling is required for XBP1 (unspliced and spliced)-mediated effects on antiestrogen responsiveness and cell fate decisions in breast cancerTargeting cell migration and the endoplasmic reticulum stress response with calmodulin antagonists: a clinically tested small molecule phenocopy of SEC62 gene silencing in human tumor cells.Isodeoxyelephantopin from Elephantopus scaber (Didancao) induces cell cycle arrest and caspase-3-mediated apoptosis in breast carcinoma T47D cells and lung carcinoma A549 cells.High-throughput screen of natural product libraries for hsp90 inhibitors.Evaluation of antioxidant and anticancer activity of extract and fractions of Nardostachys jatamansi DC in breast carcinomaIn vitro cytotoxicity of Artemisia vulgaris L. essential oil is mediated by a mitochondria-dependent apoptosis in HL-60 leukemic cell lineAdvances in the research and development of natural health products as main stream cancer therapeuticsBritannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.Fluorinated amino-derivatives of the sesquiterpene lactone, parthenolide, as (19)f NMR probes in deuterium-free environments.Anti-Inflammatory and Cytostatic Activities of a Parthenolide-Like Sesquiterpene Lactone from Cota palaestina subsp. syriaca.Synergistic effects of the sesquiterpene lactone, EPD, with cisplatin and paclitaxel in ovarian cancer cells.Phytometabolite Dehydroleucodine Induces Cell Cycle Arrest, Apoptosis, and DNA Damage in Human Astrocytoma Cells through p73/p53 RegulationIsoalantolactone Enhances the Radiosensitivity of UMSCC-10A Cells via Specific Inhibition of Erk1/2 Phosphorylation.Sesquiterpene lactone! a promising antioxidant, anticancer and moderate antinociceptive agent from Artemisia macrocephala jacquem.Activation of antioxidant response element in mouse primary cortical cultures with sesquiterpene lactones isolated from Tanacetum parthenium.Small molecule RL71 targets SERCA2 at a novel site in the treatment of human colorectal cancer.Micheliolide inhibits LPS-induced inflammatory response and protects mice from LPS challenge.The Nonartemisinin Sesquiterpene Lactones Parthenin and Parthenolide Block Plasmodium falciparum Sexual Stage Transmission.EM23, A Natural Sesquiterpene Lactone from Elephantopus mollis, Induces Apoptosis in Human Myeloid Leukemia Cells through Thioredoxin- and Reactive Oxygen Species-Mediated Signaling Pathways.Topical Administration of Manuka Oil Prevents UV-B Irradiation-Induced Cutaneous Photoaging in MiceSesquiterpenoids lactones: benefits to plants and people.Dual-functional abeo-taxane derivatives destabilizing microtubule equilibrium and inhibiting NF-κB activationComparative Transcriptome Analysis Identifies Putative Genes Involved in the Biosynthesis of Xanthanolides in Xanthium strumarium L.
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P2860
What made sesquiterpene lactones reach cancer clinical trials?
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
What made sesquiterpene lactones reach cancer clinical trials?
@ast
What made sesquiterpene lactones reach cancer clinical trials?
@en
What made sesquiterpene lactones reach cancer clinical trials?
@nl
type
label
What made sesquiterpene lactones reach cancer clinical trials?
@ast
What made sesquiterpene lactones reach cancer clinical trials?
@en
What made sesquiterpene lactones reach cancer clinical trials?
@nl
prefLabel
What made sesquiterpene lactones reach cancer clinical trials?
@ast
What made sesquiterpene lactones reach cancer clinical trials?
@en
What made sesquiterpene lactones reach cancer clinical trials?
@nl
P50
P1433
P1476
What made sesquiterpene lactones reach cancer clinical trials?
@en
P2093
Akram Ghantous
Hala Gali-Muhtasib
P304
P356
10.1016/J.DRUDIS.2010.06.002
P577
2010-06-09T00:00:00Z