Human immunodeficiency virus type 1 can establish latent infection in resting CD4+ T cells in the absence of activating stimuli.
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HIV restriction in quiescent CD4⁺ T cellsUnderstanding HIV latency: the road to an HIV cureAn in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patientsDirectly infected resting CD4+T cells can produce HIV Gag without spreading infection in a model of HIV latencySAMHD1 restricts HIV-1 infection in resting CD4(+) T cells.Basal shuttle of NF-kappaB/I kappaB alpha in resting T lymphocytes regulates HIV-1 LTR dependent expression.Cell-type-specific proteome and interactome: using HIV-1 Tat as a test case.Small-molecule screening using a human primary cell model of HIV latency identifies compounds that reverse latency without cellular activationHIV persistence: chemokines and their signalling pathways.Activation of HIV transcription by the viral Tat protein requires a demethylation step mediated by lysine-specific demethylase 1 (LSD1/KDM1).Combination of biological screening in a cellular model of viral latency and virtual screening identifies novel compounds that reactivate HIV-1A flexible model of HIV-1 latency permitting evaluation of many primary CD4 T-cell reservoirs.Establishment of HIV-1 latency in resting CD4+ T cells depends on chemokine-induced changes in the actin cytoskeleton.Provirus activation plus CD59 blockage triggers antibody-dependent complement-mediated lysis of latently HIV-1-infected cells.Cell-to-cell transmission can overcome multiple donor and target cell barriers imposed on cell-free HIV.Towards an HIV cure: a global scientific strategyPharmaceutical approaches to eradication of persistent HIV infection.Gag-positive reservoir cells are susceptible to HIV-specific cytotoxic T lymphocyte mediated clearance in vitro and can be detected in vivo [corrected]Calcium/calcineurin synergizes with prostratin to promote NF-κB dependent activation of latent HIVHigh-throughput screening uncovers a compound that activates latent HIV-1 and acts cooperatively with a histone deacetylase (HDAC) inhibitor.Myeloid dendritic cells induce HIV-1 latency in non-proliferating CD4+ T cells.Selective HDAC inhibition for the disruption of latent HIV-1 infection.A primary CD4(+) T cell model of HIV-1 latency established after activation through the T cell receptor and subsequent return to quiescenceEradicating HIV-1 infection: seeking to clear a persistent pathogen.Spinoculation triggers dynamic actin and cofilin activity that facilitates HIV-1 infection of transformed and resting CD4 T cells.HIV Latency Is Established Directly and Early in Both Resting and Activated Primary CD4 T Cells.Immediate activation fails to rescue efficient human immunodeficiency virus replication in quiescent CD4+ T cells.HIV-1 Vif promotes the G₁- to S-phase cell-cycle transition.Leveraging Cancer Therapeutics for the HIV Cure Agenda: Current Status and Future DirectionsThe role of antigen presenting cells in the induction of HIV-1 latency in resting CD4(+) T-cells.Understanding Factors That Modulate the Establishment of HIV Latency in Resting CD4+ T-Cells In Vitro.HIV persistence in the setting of antiretroviral therapy: when, where and how does HIV hide?A new way of measuring apoptosis by absolute quantitation of inter-nucleosomally fragmented genomic DNA.Latent HIV-1 is activated by exosomes from cells infected with either replication-competent or defective HIV-1.Activation and lysis of human CD4 cells latently infected with HIV-1Human immunodeficiency virus (HIV) latency: the major hurdle in HIV eradicationMicroRNA-mediated restriction of HIV-1 in resting CD4+ T cells and monocytes.HIV-1 latency and virus production from unintegrated genomes following direct infection of resting CD4 T cells.Small Molecule Inhibitors of BAF; A Promising Family of Compounds in HIV-1 Latency ReversalHIV latency: experimental systems and molecular models.
P2860
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P2860
Human immunodeficiency virus type 1 can establish latent infection in resting CD4+ T cells in the absence of activating stimuli.
description
2005 nî lūn-bûn
@nan
2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Human immunodeficiency virus t ...... absence of activating stimuli.
@ast
Human immunodeficiency virus t ...... absence of activating stimuli.
@en
Human immunodeficiency virus t ...... absence of activating stimuli.
@nl
type
label
Human immunodeficiency virus t ...... absence of activating stimuli.
@ast
Human immunodeficiency virus t ...... absence of activating stimuli.
@en
Human immunodeficiency virus t ...... absence of activating stimuli.
@nl
prefLabel
Human immunodeficiency virus t ...... absence of activating stimuli.
@ast
Human immunodeficiency virus t ...... absence of activating stimuli.
@en
Human immunodeficiency virus t ...... absence of activating stimuli.
@nl
P2093
P2860
P1433
P1476
Human immunodeficiency virus t ...... absence of activating stimuli.
@en
P2093
Chuanzhao Li
Clifford Baytop
Jianqing J Yu
Jihong Dai
Richard Schretzenmair
Ted Theodosopoulos
Una O'Doherty
William J Swiggard
P2860
P304
14179-14188
P356
10.1128/JVI.79.22.14179-14188.2005
P407
P577
2005-11-01T00:00:00Z