PBPK modelling of inter-individual variability in the pharmacokinetics of environmental chemicals.
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Recommendations for biomonitoring of emergency responders: focus on occupational health investigations and occupational health researchInnovative clinical trial design for pediatric therapeuticsNovel in vitro and mathematical models for the prediction of chemical toxicityAdvancing human health risk assessment: integrating recent advisory committee recommendationsSpatio-temporal simulation of first pass drug perfusion in the liverBayesian Analysis of a Lipid-Based Physiologically Based Toxicokinetic Model for a Mixture of PCBs in RatsPredicting volume of distribution with decision tree-based regression methods using predicted tissue:plasma partition coefficientsPhysiologically Based Pharmacokinetic (PBPK) Modeling and Simulation Approaches: A Systematic Review of Published Models, Applications, and Model VerificationAddressing human variability in next-generation human health risk assessments of environmental chemicalsA mechanistic, model-based approach to safety assessment in clinical developmentRepresentative Sinusoids for Hepatic Four-Scale Pharmacokinetics SimulationsBayesian Population Physiologically-Based Pharmacokinetic (PBPK) Approach for a Physiologically Realistic Characterization of Interindividual Variability in Clinically Relevant PopulationsCombining the 'bottom up' and 'top down' approaches in pharmacokinetic modelling: fitting PBPK models to observed clinical dataTranslational learning from clinical studies predicts drug pharmacokinetics across patient populations.Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.Reconstruction of Exposure to m-Xylene from Human Biomonitoring Data Using PBPK Modelling, Bayesian Inference, and Markov Chain Monte Carlo Simulation.A mechanistic modeling framework for predicting metabolic interactions in complex mixtures.A physiologically based pharmacokinetic model for capreomycin.Advancing In Vitro-In Vivo Extrapolations of Mechanism-Specific Toxicity Data Through Toxicokinetic Modeling.Approaches to integrated monitoring for environmental health impact assessment.A multi-scale modeling framework for individualized, spatiotemporal prediction of drug effects and toxicological risk.Toward the development of an in silico human model for indoor environmental design.Physiologically based pharmacokinetic models: integration of in silico approaches with micro cell culture analogues.Fixed-dose combination orally disintegrating tablets to treat cardiovascular disease: formulation, in vitro characterization and physiologically based pharmacokinetic modeling to assess bioavailability.An update on computational oral absorption simulation.Genome-scale modeling of human metabolism - a systems biology approach.Organ-on-a-chip technology and microfluidic whole-body models for pharmacokinetic drug toxicity screening.Modeling bioavailability to organs protected by biological barriers.Performance Assessment and Translation of Physiologically Based Pharmacokinetic Models from acslX™ to Berkeley Madonna™, MATLAB®, and R language: Oxytetracycline and Gold Nanoparticles as Case Examples.A review of quantitative structure-property relationships for the fate of ionizable organic chemicals in water matrices and identification of knowledge gaps.Probabilistic integrated risk assessment of human exposure risk to environmental bisphenol A pollution sources.Modeling Pharmacokinetics.A bayesian perspective on estimation of variability and uncertainty in mechanism-based modelsUsing Bayesian-PBPK modeling for assessment of inter-individual variability and subgroup stratification.Microtechnology-Based Multi-Organ Models.Adverse outcome pathways: opportunities, limitations and open questionsHigh-Throughput Analysis of Ovarian Cycle Disruption by Mixtures of Aromatase Inhibitors.International Frameworks Dealing with Human Risk Assessment of Combined Exposure to Multiple ChemicalsModern methodologies and tools for human hazard assessment of chemicalsVirtual population generator for human cardiomyocytes parameters: in silico drug cardiotoxicity assessment.
P2860
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P2860
PBPK modelling of inter-individual variability in the pharmacokinetics of environmental chemicals.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
PBPK modelling of inter-indivi ...... cs of environmental chemicals.
@ast
PBPK modelling of inter-indivi ...... cs of environmental chemicals.
@en
PBPK modelling of inter-indivi ...... cs of environmental chemicals.
@nl
type
label
PBPK modelling of inter-indivi ...... cs of environmental chemicals.
@ast
PBPK modelling of inter-indivi ...... cs of environmental chemicals.
@en
PBPK modelling of inter-indivi ...... cs of environmental chemicals.
@nl
prefLabel
PBPK modelling of inter-indivi ...... cs of environmental chemicals.
@ast
PBPK modelling of inter-indivi ...... cs of environmental chemicals.
@en
PBPK modelling of inter-indivi ...... cs of environmental chemicals.
@nl
P1433
P1476
PBPK modelling of inter-indivi ...... cs of environmental chemicals.
@en
P2093
Harvey J Clewell
Masoud Jamei
P304
P356
10.1016/J.TOX.2010.06.007
P407
P577
2010-06-30T00:00:00Z