Enhanced efficiency of prodrug activation therapy by tumor-selective replicating retrovirus vectors armed with the Escherichia coli purine nucleoside phosphorylase gene.
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Insights into Phosphate Cooperativity and Influence of Substrate Modifications on Binding and Catalysis of Hexameric Purine Nucleoside PhosphorylasesCurrent status of gene therapy for brain tumors.Radiosensitization of gliomas by intracellular generation of 5-fluorouracil potentiates prodrug activator gene therapy with a retroviral replicating vector.Local bacteria affect the efficacy of chemotherapeutic drugs.In vivo antitumor activity of intratumoral fludarabine phosphate in refractory tumors expressing E. coli purine nucleoside phosphorylase.Promotion of metastasis of thyroid cancer cells via NRP-2-mediated induction.Strategies in gene therapy for glioblastoma.PRE-CLINICAL AND CLINICAL VALIDATION OF AN ANTI-CANCER MODALITY THAT ABLATES REFRACTORY, LOW GROWTH FRACTION TUMORS.Gene therapy and virotherapy: novel therapeutic approaches for brain tumors.Enzymes to die for: exploiting nucleotide metabolizing enzymes for cancer gene therapy.Targeted expression of Escherichia coli purine nucleoside phosphorylase and Fludara® for prostate cancer therapy.RNAi-mediated gene silencing in tumour tissue using replication-competent retroviral vectors.Effect of expression of adenine phosphoribosyltransferase on the in vivo anti-tumor activity of prodrugs activated by E. coli purine nucleoside phosphorylase.Retroviral replicating vector-mediated gene therapy achieves long-term control of tumor recurrence and leads to durable anticancer immunity.Stable knockdown of CREB, HIF-1 and HIF-2 by replication-competent retroviruses abrogates the responses to hypoxia in hepatocellular carcinomaTumor-specific suicide gene therapy for hepatocellular carcinoma by transcriptionally targeted retroviral replicating vectors.Thermus thermophilus nucleoside phosphorylases active in the synthesis of nucleoside analogues.Efficient Fludarabine-Activating PNP From Archaea as a Guidance for Redesign the Active Site of E. Coli PNP.An ultrasonic nanobubble-mediated PNP/fludarabine suicide gene system: A new approach for the treatment of hepatocellular carcinoma.Gene therapy and targeted toxins for glioma
P2860
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P2860
Enhanced efficiency of prodrug activation therapy by tumor-selective replicating retrovirus vectors armed with the Escherichia coli purine nucleoside phosphorylase gene.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Enhanced efficiency of prodrug ...... nucleoside phosphorylase gene.
@ast
Enhanced efficiency of prodrug ...... nucleoside phosphorylase gene.
@en
Enhanced efficiency of prodrug ...... nucleoside phosphorylase gene.
@nl
type
label
Enhanced efficiency of prodrug ...... nucleoside phosphorylase gene.
@ast
Enhanced efficiency of prodrug ...... nucleoside phosphorylase gene.
@en
Enhanced efficiency of prodrug ...... nucleoside phosphorylase gene.
@nl
prefLabel
Enhanced efficiency of prodrug ...... nucleoside phosphorylase gene.
@ast
Enhanced efficiency of prodrug ...... nucleoside phosphorylase gene.
@en
Enhanced efficiency of prodrug ...... nucleoside phosphorylase gene.
@nl
P2093
P2860
P356
P1433
P1476
Enhanced efficiency of prodrug ...... nucleoside phosphorylase gene.
@en
P2093
E J Sorscher
N Kasahara
W B Parker
P2860
P2888
P304
P356
10.1038/CGT.2010.17
P577
2010-05-14T00:00:00Z