Exclusive ubiquitination and sumoylation on overlapping lysine residues mediate NF-kappaB activation by the human T-cell leukemia virus tax oncoprotein.
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The HTLV-1 Tax interactomeHighlights on distinctive structural and functional properties of HTLV Tax proteinsThe HTLV-1 Tax protein inhibits formation of stress granules by interacting with histone deacetylase 6Essential role for TAX1BP1 in the termination of TNF-alpha-, IL-1- and LPS-mediated NF-kappaB and JNK signalingMolecular Studies of HTLV-1 Replication: An UpdateCharacterization of Fusion Determinants Points to the Involvement of Three Discrete Regions of Both E1 and E2 Glycoproteins in the Membrane Fusion Process of Hepatitis C VirusHTLV-1 Tax Functions as a Ubiquitin E3 Ligase for Direct IKK Activation via Synthesis of Mixed-Linkage Polyubiquitin ChainsTax-1 and Tax-2 similarities and differences: focus on post-translational modifications and NF-κB activation.NRP/Optineurin Cooperates with TAX1BP1 to potentiate the activation of NF-kappaB by human T-lymphotropic virus type 1 tax protein.Modification of small hepatitis delta virus antigen by SUMO protein.Acetylation of the human T-cell leukemia virus type 1 Tax oncoprotein by p300 promotes activation of the NF-kappaB pathway.SUMO-interacting motifs of human TRIM5α are important for antiviral activitySumo-dependent substrate targeting of the SUMO protease Ulp1A non-SUMOylated tax protein is still functional for NF-κB pathway activation.HTLV-1 tax-induced rapid senescence is driven by the transcriptional activity of NF-κB and depends on chronically activated IKKα and p65/RelA.The transcription profile of Tax-3 is more similar to Tax-1 than Tax-2: insights into HTLV-3 potential leukemogenic properties.Genotoxic stress and cellular stress alter the subcellular distribution of human T-cell leukemia virus type 1 tax through a CRM1-dependent mechanismRole of post-translational modifications of HTLV-1 Tax in NF-κB activation.Ubiquitin-specific peptidase 20 targets TRAF6 and human T cell leukemia virus type 1 tax to negatively regulate NF-kappaB signalingHuman T-cell lymphotropic virus: a model of NF-κB-associated tumorigenesisSuppression of HTLV-1 replication by Tax-mediated rerouting of the p13 viral protein to nuclear speckles.Mutual regulation between deubiquitinase CYLD and retroviral oncoprotein TaxHuman T Lymphotropic Virus Type 1 (HTLV-1): Molecular Biology and Oncogenesis.Move or die: the fate of the Tax oncoprotein of HTLV-1.Human T-cell lymphotropic virus type 3 (HTLV-3)- and HTLV-4-derived antisense transcripts encode proteins with similar Tax-inhibiting functions but distinct subcellular localizationHuman T-cell leukemia virus type-1 Tax oncoprotein regulates G-protein signaling.HTLV-1 Tax Stimulates Ubiquitin E3 Ligase, Ring Finger Protein 8, to Assemble Lysine 63-Linked Polyubiquitin Chains for TAK1 and IKK Activation.The Sumo-targeted ubiquitin ligase RNF4 regulates the localization and function of the HTLV-1 oncoprotein Tax.The tumor suppressor gene WWOX links the canonical and noncanonical NF-κB pathways in HTLV-I Tax-mediated tumorigenesisTax protein-induced expression of antiapoptotic Bfl-1 protein contributes to survival of human T-cell leukemia virus type 1 (HTLV-1)-infected T-cellsProgressive loss of CD3 expression after HTLV-I infection results from chromatin remodeling affecting all the CD3 genes and persists despite early viral genes silencing.HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains.The human T-cell leukemia virus type 1 Tax oncoprotein requires the ubiquitin-conjugating enzyme Ubc13 for NF-kappaB activation.Low nuclear body formation and tax SUMOylation do not prevent NF-kappaB promoter activationHTLV tax: a fascinating multifunctional co-regulator of viral and cellular pathwaysUbiquitination of HTLV-I Tax in response to DNA damage regulates nuclear complex formation and nuclear export.Ubiquitination and sumoylation of the HTLV-2 Tax-2B protein regulate its NF-κB activity: a comparative study with the HTLV-1 Tax-1 protein.NF-kappaB activation in development and progression of cancer.Regulation of the nucleocytoplasmic trafficking of viral and cellular proteins by ubiquitin and small ubiquitin-related modifiers.Profiling of ubiquitin-like modifications reveals features of mitotic control.
P2860
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P2860
Exclusive ubiquitination and sumoylation on overlapping lysine residues mediate NF-kappaB activation by the human T-cell leukemia virus tax oncoprotein.
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Exclusive ubiquitination and s ...... eukemia virus tax oncoprotein.
@ast
Exclusive ubiquitination and s ...... eukemia virus tax oncoprotein.
@en
Exclusive ubiquitination and s ...... eukemia virus tax oncoprotein.
@nl
type
label
Exclusive ubiquitination and s ...... eukemia virus tax oncoprotein.
@ast
Exclusive ubiquitination and s ...... eukemia virus tax oncoprotein.
@en
Exclusive ubiquitination and s ...... eukemia virus tax oncoprotein.
@nl
prefLabel
Exclusive ubiquitination and s ...... eukemia virus tax oncoprotein.
@ast
Exclusive ubiquitination and s ...... eukemia virus tax oncoprotein.
@en
Exclusive ubiquitination and s ...... eukemia virus tax oncoprotein.
@nl
P2093
P2860
P1476
Exclusive ubiquitination and s ...... eukemia virus tax oncoprotein.
@en
P2093
Françoise Bex
Julie Lodewick
Richard B Gaynor
Robert Brasseur
Sylvie Lebrun
P2860
P304
10391-10406
P356
10.1128/MCB.25.23.10391-10406.2005
P407
P577
2005-12-01T00:00:00Z