Interleukins 19, 20, and 24 signal through two distinct receptor complexes. Differences in receptor-ligand interactions mediate unique biological functions.
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Evolutionary divergence and functions of the human interleukin (IL) gene familyCardiovascular diabetology in the core of a novel interleukins classification: the bad, the good and the aloofCloning of a new type II cytokine receptor activating signal transducer and activator of transcription (STAT)1, STAT2 and STAT3Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditionsInterleukin-24 and its receptorsMechanism of Action and Applications of Interleukin 24 in ImmunotherapyThe Role of the IL-20 Subfamily in GlaucomaStructural basis for receptor sharing and activation by interleukin-20 receptor-2 (IL-20R2) binding cytokinesToll-like receptor 2 and 4 induced interleukin-19 dampens immune reactions and associates inversely with spondyloarthritis disease activityThe Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasisThe T-cell lymphokine interleukin-26 targets epithelial cells through the interleukin-20 receptor 1 and interleukin-10 receptor 2 chainsMaturing dendritic cells are an important source of IL-29 and IL-20 that may cooperatively increase the innate immunity of keratinocytesInhibiting interleukin-19 activity ameliorates esophageal squamous cell carcinoma progressionInterleukin-19: a constituent of the regulome that controls antigen presenting cells in the lungs and airway responses to microbial productsRecombinant interleukin-24 lacks apoptosis-inducing properties in melanoma cells.Cisplatin enhances protein kinase R-like endoplasmic reticulum kinase- and CD95-dependent melanoma differentiation-associated gene-7/interleukin-24-induced killing in ovarian carcinoma cellsAstrocytes produce IL-19 in response to bacterial challenge and are sensitive to the immunosuppressive effects of this IL-10 family member.Evaluation of IL10, IL19 and IL20 gene polymorphisms and chronic hepatitis B infection outcomeMDA-7/IL-24-induced cell killing in malignant renal carcinoma cells occurs by a ceramide/CD95/PERK-dependent mechanism.Inhibition of multiple protective signaling pathways and Ad.5/3 delivery enhances mda-7/IL-24 therapy of malignant gliomaPERK-dependent regulation of ceramide synthase 6 and thioredoxin play a key role in mda-7/IL-24-induced killing of primary human glioblastoma multiforme cells.MDA-7/IL-24 as a cancer therapeutic: from bench to bedside.Enhanced apoptosis-inducing function of MDA-7/IL-24 RGD mutant via the increased adhesion to tumor cells.The development of MDA-7/IL-24 as a cancer therapeuticInterleukin-26: an IL-10-related cytokine produced by Th17 cells.The anti-inflammatory cytokine interleukin 19 is expressed by and angiogenic for human endothelial cells.IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesisEnhancing mda-7/IL-24 therapy in renal carcinoma cells by inhibiting multiple protective signaling pathways using sorafenib and by Ad.5/3 gene deliveryA serotype 5/3 adenovirus expressing MDA-7/IL-24 infects renal carcinoma cells and promotes toxicity of agents that increase ROS and ceramide levels.Anti-inflammatory cytokine interleukin-19 inhibits smooth muscle cell migration and activation of cytoskeletal regulators of VSMC motility.Kaposi's sarcoma-associated herpesvirus-encoded LANA down-regulates IL-22R1 expression through a cis-acting element within the promoter regionThe cationic cytokine IL-26 differentially modulates virus infection in culture.Interleukin-19 impairment in active Crohn's disease patients.IL-24 is expressed during wound repair and inhibits TGFalpha-induced migration and proliferation of keratinocytesmda-7/IL-24: a unique member of the IL-10 gene family promoting cancer-targeted toxicity.Splice variants of mda-7/IL-24 differentially affect survival and induce apoptosis in U2OS cells.Interleukin-22: immunobiology and pathology.Interleukin-19 acts as a negative autocrine regulator of activated microgliaEnhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) in combination with the Apogossypol derivative BI-97C1 (Sabutoclax) improves therapeutic efficacy in low CAR colorectal cancer cellsPurification, crystallization and preliminary X-ray diffraction analysis of the IL-20-IL-20R1-IL-20R2 complex.
P2860
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P2860
Interleukins 19, 20, and 24 signal through two distinct receptor complexes. Differences in receptor-ligand interactions mediate unique biological functions.
description
2002 nî lūn-bûn
@nan
2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Interleukins 19, 20, and 24 si ...... e unique biological functions.
@ast
Interleukins 19, 20, and 24 si ...... e unique biological functions.
@en
Interleukins 19, 20, and 24 si ...... e unique biological functions.
@nl
type
label
Interleukins 19, 20, and 24 si ...... e unique biological functions.
@ast
Interleukins 19, 20, and 24 si ...... e unique biological functions.
@en
Interleukins 19, 20, and 24 si ...... e unique biological functions.
@nl
prefLabel
Interleukins 19, 20, and 24 si ...... e unique biological functions.
@ast
Interleukins 19, 20, and 24 si ...... e unique biological functions.
@en
Interleukins 19, 20, and 24 si ...... e unique biological functions.
@nl
P2093
P2860
P356
P1476
Interleukins 19, 20, and 24 si ...... e unique biological functions.
@en
P2093
Cameron Brandt
Crystal Jones
Donald C Foster
Julia Parrish-Novak
Karen Madden
Laura Jelinek
Patricia A McKernan
Stephen Jaspers
P2860
P304
47517-47523
P356
10.1074/JBC.M205114200
P407
P577
2002-09-25T00:00:00Z