Modification of the cysteine residues in IkappaBalpha kinase and NF-kappaB (p65) by xanthohumol leads to suppression of NF-kappaB-regulated gene products and potentiation of apoptosis in leukemia cells
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Plumbagin inhibits proliferative and inflammatory responses of T cells independent of ROS generation but by modulating intracellular thiolsEffects of chalcone derivatives on players of the immune systemMolecular targeted approaches to cancer therapy and prevention using chalconesBotanicals and Their Bioactive Phytochemicals for Women's HealthPMS1077 sensitizes TNF-α induced apoptosis in human prostate cancer cells by blocking NF-κB signaling pathwayAn in vitro FluoroBlok tumor invasion assay.Chronic inflammation and cancer: potential chemoprevention through nuclear factor kappa B and p53 mutual antagonismXanthohumol, a Prenylated Flavonoid from Hops (Humulus lupulus), Prevents Platelet Activation in Human Platelets.Modification of cysteine 179 of IkappaBalpha kinase by nimbolide leads to down-regulation of NF-kappaB-regulated cell survival and proliferative proteins and sensitization of tumor cells to chemotherapeutic agentsXanthohumol Blocks Proliferation and Migration of Vascular Smooth Muscle Cells in Vitro and Reduces Neointima Formation in Vivo.The apoptogenic toxin AIP56 is a metalloprotease A-B toxin that cleaves NF-κb P65The role of chalcones in suppression of NF-κB-mediated inflammation and cancer.Antitumor agents 283. Further elaboration of desmosdumotin C analogs as potent antitumor agents: activation of spindle assembly checkpoint as possible mode of actionDietary chalcones with chemopreventive and chemotherapeutic potential.NF-κB addiction and its role in cancer: 'one size does not fit all'.NF-kappaB and cancer: how intimate is this relationshipXanthohumol induces growth inhibition and apoptosis in ca ski human cervical cancer cells.Protective effect of xanthohumol on toxin-induced liver inflammation and fibrosisRadiation, inflammation, and immune responses in cancerDiphenyldifluoroketone EF24 Suppresses Pro-inflammatory Interleukin-1 receptor 1 and Toll-like Receptor 4 in lipopolysaccharide-stimulated dendritic cellsp53 causes butein‑mediated apoptosis of chronic myeloid leukemia cells.Mutation of cysteine 46 in IKK-beta increases inflammatory responses.Cancer and diet: How are they related?NADPH:quinone oxidoreductase 1 regulates host susceptibility to ozone via isoprostane generation.Cancer cell signaling pathways targeted by spice-derived nutraceuticals.Growth inhibitory and apoptosis-inducing effects of xanthohumol, a prenylated chalone present in hops, in human prostate cancer cells.Immunomodulatory activity of xanthohumol: inhibition of T cell proliferation, cell-mediated cytotoxicity and Th1 cytokine production through suppression of NF-kappaB.Differential regulation of detoxification enzymes in hepatic and mammary tissue by hops (Humulus lupulus) in vitro and in vivo.Chemical biology of inflammatory cytokine signaling.Triptolide inhibits the proliferation of cells from lymphocytic leukemic cell lines in association with downregulation of NF-κB activity and miR-16-1*.NF-κB as a potential therapeutic target in myelodysplastic syndromes and acute myeloid leukemia.An update on antitumor activity of naturally occurring chalcones.Dietary phytochemicals alter epigenetic events and signaling pathways for inhibition of metastasis cascade: phytoblockers of metastasis cascade.Chinese medicines and bioactive compounds for treatment of stroke.Pharmacological profile of xanthohumol, a prenylated flavonoid from hops (Humulus lupulus).Diverse Molecular Targets for Chalcones with Varied Bioactivities.Adamantyl arotinoids that inhibit IκB kinase α and IκB kinase β.Prenylated chalcone xanthohumol associates with histones in breast cancer cells--a novel target identified by a monoclonal antibody.Chalcone: A Privileged Structure in Medicinal Chemistry.Transactivation of gene expression by NF-κB is dependent on thioredoxin reductase activity.
P2860
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P2860
Modification of the cysteine residues in IkappaBalpha kinase and NF-kappaB (p65) by xanthohumol leads to suppression of NF-kappaB-regulated gene products and potentiation of apoptosis in leukemia cells
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Modification of the cysteine r ...... of apoptosis in leukemia cells
@ast
Modification of the cysteine r ...... of apoptosis in leukemia cells
@en
Modification of the cysteine residues in IkappaBalpha kinase and NF-kappaB
@nl
type
label
Modification of the cysteine r ...... of apoptosis in leukemia cells
@ast
Modification of the cysteine r ...... of apoptosis in leukemia cells
@en
Modification of the cysteine residues in IkappaBalpha kinase and NF-kappaB
@nl
prefLabel
Modification of the cysteine r ...... of apoptosis in leukemia cells
@ast
Modification of the cysteine r ...... of apoptosis in leukemia cells
@en
Modification of the cysteine residues in IkappaBalpha kinase and NF-kappaB
@nl
P2093
P2860
P1433
P1476
Modification of the cysteine r ...... of apoptosis in leukemia cells
@en
P2093
Ajaikumar B Kunnumakkara
Bharat B Aggarwal
Kwang S Ahn
Preetha Anand
Sunil Krishnan
Sushovan Guha
P2860
P304
P356
10.1182/BLOOD-2008-04-151944
P407
P577
2008-10-24T00:00:00Z