Human CENP-I specifies localization of CENP-F, MAD1 and MAD2 to kinetochores and is essential for mitosis.
about
The pseudo GTPase CENP-M drives human kinetochore assemblyIdentification of novel mitosis regulators through data mining with human centromere/kinetochore proteins as group queriesThe functional region of CENP-H interacts with the Nuf2 complex that localizes to centromere during mitosisZwilch, a new component of the ZW10/ROD complex required for kinetochore functionsSilencing mitosin induces misaligned chromosomes, premature chromosome decondensation before anaphase onset, and mitotic cell death.Human Zwint-1 specifies localization of Zeste White 10 to kinetochores and is essential for mitotic checkpoint signalingNEK2A interacts with MAD1 and possibly functions as a novel integrator of the spindle checkpoint signalingThe constitutive centromere component CENP-50 is required for recovery from spindle damage.Sgt1 is required for human kinetochore assemblyGene silencing of CENP-E by small interfering RNA in HeLa cells leads to missegregation of chromosomes after a mitotic delayKNL1 and the CENP-H/I/K complex coordinately direct kinetochore assembly in vertebratesShugoshin enables tension-generating attachment of kinetochores by loading Aurora to centromeresHURP controls spindle dynamics to promote proper interkinetochore tension and efficient kinetochore capture.The kinetochore protein Kis1/Eic1/Mis19 ensures the integrity of mitotic spindles through maintenance of kinetochore factors Mis6/CENP-I and CENP-ACep57 is a Mis12-interacting kinetochore protein involved in kinetochore targeting of Mad1-Mad2.A conserved role for COMA/CENP-H/I/N kinetochore proteins in the spindle checkpoint.TRAMM/TrappC12 plays a role in chromosome congression, kinetochore stability, and CENP-E recruitment.CTCF Recruits Centromeric Protein CENP-E to the Pericentromeric/Centromeric Regions of Chromosomes through Unusual CTCF-Binding SitesCENP-B interacts with CENP-C domains containing Mif2 regions responsible for centromere localizationThe CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeresDisruption of GW bodies impairs mammalian RNA interferenceDrosophila CENP-A mutations cause a BubR1-dependent early mitotic delay without normal localization of kinetochore componentsConnecting the microtubule attachment status of each kinetochore to cell cycle arrest through the spindle assembly checkpoint.CENP-I and Aurora B act as a molecular switch that ties RZZ/Mad1 recruitment to kinetochore attachment status.Spindle poisons and cell fate: a tale of two pathways.Dissection of CENP-C-directed centromere and kinetochore assemblyThe human kinetochore proteins Nnf1R and Mcm21R are required for accurate chromosome segregation.Chromosomal instability in mouse embryonic fibroblasts null for the transcriptional co-repressor Ski.Centromere fragmentation is a common mitotic defect of S and G2 checkpoint override.Human centromere repositioning "in progress"CENP-A is required for accurate chromosome segregation and sustained kinetochore association of BubR1.Evidence for somatic gene conversion and deletion in bipolar disorder, Crohn's disease, coronary artery disease, hypertension, rheumatoid arthritis, type-1 diabetes, and type-2 diabetes.CENP-A reduction induces a p53-dependent cellular senescence response to protect cells from executing defective mitoses.The spindle checkpoint, aneuploidy, and cancer.The life and miracles of kinetochores.Phylogenetic and structural analysis of centromeric DNA and kinetochore proteins.CENP-C is involved in chromosome segregation, mitotic checkpoint function, and kinetochore assembly.Essential tension and constructive destruction: the spindle checkpoint and its regulatory links with mitotic exitMapping the assembly pathways that specify formation of the trilaminar kinetochore plates in human cells.Two distinct pathways responsible for the loading of CENP-A to centromeres in the fission yeast cell cycle.
P2860
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P2860
Human CENP-I specifies localization of CENP-F, MAD1 and MAD2 to kinetochores and is essential for mitosis.
description
2003 nî lūn-bûn
@nan
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Human CENP-I specifies localiz ...... and is essential for mitosis.
@ast
Human CENP-I specifies localiz ...... and is essential for mitosis.
@en
Human CENP-I specifies localiz ...... and is essential for mitosis.
@nl
type
label
Human CENP-I specifies localiz ...... and is essential for mitosis.
@ast
Human CENP-I specifies localiz ...... and is essential for mitosis.
@en
Human CENP-I specifies localiz ...... and is essential for mitosis.
@nl
prefLabel
Human CENP-I specifies localiz ...... and is essential for mitosis.
@ast
Human CENP-I specifies localiz ...... and is essential for mitosis.
@en
Human CENP-I specifies localiz ...... and is essential for mitosis.
@nl
P2093
P356
P1433
P1476
Human CENP-I specifies localiz ...... and is essential for mitosis.
@en
P2093
James C Hittle
Kinya Yoda
Michael S Campbell
Sandra A Jablonski
Song-Tao Liu
P2888
P304
P356
10.1038/NCB953
P50
P577
2003-04-01T00:00:00Z
P5875
P6179
1017739631