Inhibition of human peptide deformylase disrupts mitochondrial function
about
Mutations in MTFMT underlie a human disorder of formylation causing impaired mitochondrial translationUnderstanding the highly efficient catalysis of prokaryotic peptide deformylases by shedding light on the determinants specifying the low activity of the human counterpartThe role of formylated peptides and formyl peptide receptor 1 in governing neutrophil function during acute inflammationOverexpression of peptide deformylase in breast, colon, and lung cancers.Structure-Based Drug Design of Small Molecule Peptide Deformylase Inhibitors to Treat Cancer.Quality control of mitochondrial protein synthesis is required for membrane integrity and cell fitness.A unique peptide deformylase platform to rationally design and challenge novel active compounds.Inhibition of human mitochondrial peptide deformylase causes apoptosis in c-myc-overexpressing hematopoietic cancers.Mitochondrial ribosomes in cancer.Interplay between N-terminal methionine excision and FtsH protease is essential for normal chloroplast development and function in Arabidopsis.
P2860
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P2860
Inhibition of human peptide deformylase disrupts mitochondrial function
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Inhibition of human peptide deformylase disrupts mitochondrial function
@ast
Inhibition of human peptide deformylase disrupts mitochondrial function
@en
Inhibition of human peptide deformylase disrupts mitochondrial function
@nl
type
label
Inhibition of human peptide deformylase disrupts mitochondrial function
@ast
Inhibition of human peptide deformylase disrupts mitochondrial function
@en
Inhibition of human peptide deformylase disrupts mitochondrial function
@nl
prefLabel
Inhibition of human peptide deformylase disrupts mitochondrial function
@ast
Inhibition of human peptide deformylase disrupts mitochondrial function
@en
Inhibition of human peptide deformylase disrupts mitochondrial function
@nl
P2093
P2860
P356
P1476
Inhibition of human peptide deformylase disrupts mitochondrial function
@en
P2093
Aneesh Sheth
David A Scheinberg
Giovanni Manfredi
Guangli Yang
Jeffrey Gardner
Mark L Heaney
P2860
P304
P356
10.1128/MCB.00469-10
P407
P577
2010-08-30T00:00:00Z