The ESEV PDZ-binding motif of the avian influenza A virus NS1 protein protects infected cells from apoptosis by directly targeting Scribble. - sprookjes - yvandenbroek - TriplyDB

The ESEV PDZ-binding motif of the avian influenza A virus NS1 protein protects infected cells from apoptosis by directly targeting Scribble.

The ESEV PDZ-binding motif of the avian influenza A virus NS1 protein protects infected cells from apoptosis by directly targeting Scribble.

http://www.wikidata.org/entity/Q34190628

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Viral Interactions with PDZ Domain-Containing Proteins-An Oncogenic Trait?Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary gland A Transient Homotypic Interaction Model for the Influenza A Virus NS1 Protein Effector Domain PDlim2 Selectively Interacts with the PDZ Binding Motif of Highly Pathogenic Avian H5N1 Influenza A Virus NS1 The Influenza A Virus Protein NS1 Displays Structural Polymorphism The interactomes of influenza virus NS1 and NS2 proteins identify new host factors and provide insights for ADAR1 playing a supportive role in virus replication Networks of Host Factors that Interact with NS1 Protein of Influenza A Virus Effects of the C-terminal truncation in NS1 protein of the 2009 pandemic H1N1 influenza virus on host gene expression.Reassortment of NS segments modifies highly pathogenic avian influenza virus interaction with avian hosts and host cells.Evolutionarily conserved bias of amino-acid usage refines the definition of PDZ-binding motif.The PDZ-ligand and Src-homology type 3 domains of epidemic avian influenza virus NS1 protein modulate human Src kinase activity during viral infection.Differential regulation of cell-cell contact, invasion and anoikis by hScrib and hDlg in keratinocytes Regulation of interferon-β by MAGI-1 and its interaction with influenza A virus NS1 protein with ESEV PBM Differential cellular gene expression in duck trachea infected with a highly or low pathogenic H5N1 avian influenza virus.A comprehensive map of the influenza A virus replication cycle The distinct binding properties between avian/human influenza A virus NS1 and Postsynaptic density protein-95 (PSD-95), and inhibition of nitric oxide production.Comprehensive proteomic analysis of influenza virus polymerase complex reveals a novel association with mitochondrial proteins and RNA polymerase accessory factors Putting into practice domain-linear motif interaction predictions for exploration of protein networks.Emerging theme: cellular PDZ proteins as common targets of pathogenic viruses.High throughput method to quantify anterior-posterior polarity of T-cells and epithelial cells.The NS1 protein of influenza A virus suppresses interferon-regulated activation of antigen-presentation and immune-proteasome pathways.The polarity protein Scrib mediates epidermal development and exerts a tumor suppressive function during skin carcinogenesis.Innate immunity to H5N1 influenza viruses in humans.Synergistic effect of the PDZ and p85β-binding domains of the NS1 protein on virulence of an avian H5N1 influenza A virus.Viral and host factors required for avian H5N1 influenza A virus replication in mammalian cells Variability among the neuraminidase, non-structural 1 and PB1-F2 proteins in the influenza A virus genome.Apoptosis signaling in influenza virus propagation, innate host defense, and lung injury.Broad-spectrum antiviral agents.Structure-Guided Functional Annotation of the Influenza A Virus NS1 Protein Reveals Dynamic Evolution of the p85β-Binding Site During Circulation in Humans.The avian influenza virus NS1 ESEV PDZ binding motif associates with Dlg1 and Scribble to disrupt cellular tight junctions.H5N1 influenza virulence, pathogenicity and transmissibility: what do we know?Improved transient protein expression by pFluNS1 plasmid.Effective inhibition of mRNA accumulation and protein expression of H5N1 avian influenza virus NS1 gene in vitro by small interfering RNAs.Analysis of the PDZ binding specificities of Influenza A virus NS1 proteins.Shrimp miR-12 Suppresses White Spot Syndrome Virus Infection by Synchronously Triggering Antiviral Phagocytosis and Apoptosis Pathways.Phylogeny, Pathogenicity, and Transmission of H5N1 Avian Influenza Viruses in Chickens.Influenza A Virus-Host Protein Interactions Control Viral Pathogenesis.The mechanism and implications of hScrib regulation of ERK.Two highly pathogenic avian influenza H5N1 viruses of clade 2.3.2.1 with similar genetic background but with different pathogenicity in mice and ducks.Decreased apoptosis and persistence of the common nephric duct during the development of an aberrant vesicoureteral junction in Dlg1 gene-targeted mice.

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P2860

The ESEV PDZ-binding motif of the avian influenza A virus NS1 protein protects infected cells from apoptosis by directly targeting Scribble.

http://www.wikidata.org/entity/Q34190628

description

2010 nî lūn-bûn

@nan

2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年学术文章

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2010年学术文章

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2010年学术文章

@zh-hans

2010年学术文章

@zh-my

2010年学术文章

@zh-sg

2010年學術文章

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The ESEV PDZ-binding motif of ...... y directly targeting Scribble.

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The ESEV PDZ-binding motif of ...... y directly targeting Scribble.

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Journal of Virology

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The ESEV PDZ-binding motif of ...... y directly targeting Scribble.

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Andrew P Rice

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Eugene C Dow

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Hongbing Liu

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Lisa Golebiewski

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Robert M Krug

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Ronald T Javier

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P2860

Pathology, molecular biology, and pathogenesis of avian influenza A (H5N1) infection in humans

Influenza A virus NS1 protein binds p85beta and activates phosphatidylinositol-3-kinase signaling

Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I

Human scribble, a novel tumor suppressor identified as a target of high-risk HPV E6 for ubiquitin-mediated degradation, interacts with adenomatous polyposis coli

Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma

Identification of MAGI-3 as a transforming growth factor-alpha tail binding protein

Multi-PDZ domain protein MUPP1 is a cellular target for both adenovirus E4-ORF1 and high-risk papillomavirus type 18 E6 oncoproteins

Influenza A virus NS1 protein targets poly(A)-binding protein II of the cellular 3'-end processing machinery.

MAGI-1 is required for Rap1 activation upon cell-cell contact and for enhancement of vascular endothelial cadherin-mediated cell adhesion.

Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase

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11164-11174

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scholarly article

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10.1128/JVI.01278-10

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21

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84

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2010-08-11T00:00:00Z

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20702615

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apoptotic process

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2953166

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