Quantitative optical imaging of primary tumor organoid metabolism predicts drug response in breast cancer.
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Zebrafish small molecule screens: Taking the phenotypic plungeImaging metabolic heterogeneity in cancerEstrogen as Jekyll and Hyde: regulation of cell deathDeconvolution of fluorescence lifetime imaging microscopy by a library of exponentials.Big-data-based edge biomarkers: study on dynamical drug sensitivity and resistance in individuals.Correlating two-photon excited fluorescence imaging of breast cancer cellular redox state with seahorse flux analysis of normalized cellular oxygen consumption.Temporal binning of time-correlated single photon counting data improves exponential decay fits and imaging speed.Metabolic Imaging of Head and Neck Cancer OrganoidsApplying phasor approach analysis of multiphoton FLIM measurements to probe the metabolic activity of three-dimensional in vitro cell culture models.Drug response in organoids generated from frozen primary tumor tissues.Optical Imaging of Drug-Induced Metabolism Changes in Murine and Human Pancreatic Cancer Organoids Reveals Heterogeneous Drug Response.Changes in autofluorescence based organoid model of muscle invasive urinary bladder cancer.Imaging Sensitivity of Quiescent Cancer Cells to Metabolic Perturbations in Bone Marrow SpheroidsOptical redox ratio identifies metastatic potential-dependent changes in breast cancer cell metabolism.Biological Networks Governing the Acquisition, Maintenance, and Dissolution of Pluripotency: Insights from Functional Genomics Approaches.Identification of selective cytotoxic and synthetic lethal drug responses in triple negative breast cancer cells.The development of high-content screening (HCS) technology and its importance to drug discovery.Blind deconvolution estimation of fluorescence measurements through quadratic programming.Deciphering single cell metabolism by coherent Raman scattering microscopy.Autofluorescence imaging captures heterogeneous drug response differences between 2D and 3D breast cancer cultures.Optical metabolic imaging quantifies heterogeneous cell populations.Investigation of Mitochondrial Metabolic Response to Doxorubicin in Prostate Cancer Cells: An NADH, FAD and Tryptophan FLIM Assay.Real-time quantitative analysis of metabolic flux in live cells using a hyperpolarized micromagnetic resonance spectrometerMALDI Mass Spectrometry Imaging for Evaluation of Therapeutics in Colorectal Tumor Organoids.Intestinal Stem Cells to Advance Drug Development, Precision, and Regenerative Medicine: A Paradigm Shift in Translational Research.Three-Dimensional Tissue Models and Available Probes for Multi-Parametric Live Cell Microscopy: A Brief Overview.Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models.Using 3D Organoid Cultures to Model Intestinal Physiology and Colorectal Cancer.Optical imaging of radiation-induced metabolic changes in radiation-sensitive and resistant cancer cells.Autofluorescence imaging identifies tumor cell-cycle status on a single-cell level.Hydrogen peroxide modulates energy metabolism and oxidative stress in cultures of permanent human Müller cells MIO-M1.Correlative NAD(P)H-FLIM and oxygen sensing-PLIM for metabolic mapping.Recent advances in cancer metabolism: a technological perspective.Quantitative evaluation of redox ratio and collagen characteristics during breast cancer chemotherapy using two-photon intrinsic imaging.Pancreas 3D Organoids: Current and Future Aspects as a Research Platform for Personalized Medicine in Pancreatic Cancer.Protein-bound NAD(P)H Lifetime is Sensitive to Multiple Fates of Glucose Carbon.Mapping metabolic changes by noninvasive, multiparametric, high-resolution imaging using endogenous contrast.A Radiosensitizing Inhibitor of HIF-1 alters the Optical Redox State of Human Lung Cancer Cells In Vitro.Near-simultaneous quantification of glucose uptake, mitochondrial membrane potential, and vascular parameters in murine flank tumors using quantitative diffuse reflectance and fluorescence spectroscopy.Nonlinear optical microscopy: Endogenous signals and exogenous probes
P2860
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P2860
Quantitative optical imaging of primary tumor organoid metabolism predicts drug response in breast cancer.
description
2014 nî lūn-bûn
@nan
2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Quantitative optical imaging o ...... rug response in breast cancer.
@ast
Quantitative optical imaging o ...... rug response in breast cancer.
@en
Quantitative optical imaging o ...... rug response in breast cancer.
@nl
type
label
Quantitative optical imaging o ...... rug response in breast cancer.
@ast
Quantitative optical imaging o ...... rug response in breast cancer.
@en
Quantitative optical imaging o ...... rug response in breast cancer.
@nl
prefLabel
Quantitative optical imaging o ...... rug response in breast cancer.
@ast
Quantitative optical imaging o ...... rug response in breast cancer.
@en
Quantitative optical imaging o ...... rug response in breast cancer.
@nl
P2093
P2860
P1433
P1476
Quantitative optical imaging o ...... drug response in breast cancer
@en
P2093
Alex J Walsh
Carlos L Arteaga
Luigi Aurisicchio
Melinda E Sanders
Melissa C Skala
Rebecca S Cook
P2860
P304
P356
10.1158/0008-5472.CAN-14-0663
P407
P577
2014-08-06T00:00:00Z