Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia. - sprookjes - yvandenbroek - TriplyDB

Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia.

Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia.

http://www.wikidata.org/entity/Q34268301

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The Role of Ectonucleotidases CD39 and CD73 and Adenosine Signaling in Solid Organ Transplantation Clock genes in hypertension: novel insights from rodent models Attenuating myocardial ischemia by targeting A2B adenosine receptors Circadian influences on myocardial infarction Cardioprotective Signature of Short-Term Caloric Restriction HIF1A reduces acute lung injury by optimizing carbohydrate metabolism in the alveolar epithelium Actions of adenosine on cullin neddylation: implications for inflammatory responses The Many Faces of the A2b Adenosine Receptor in Cardiovascular and Metabolic Diseases Circadian molecular clock in lung pathophysiology The vascular clock system generates the intrinsic circadian rhythm of vascular contractility Cardiopulmonary bypass during cardiac surgery modulates systemic inflammation by affecting different steps of the leukocyte recruitment cascade Cardiac Per2 functions as novel link between fatty acid metabolism and myocardial inflammation during ischemia and reperfusion injury of the heart Adenosine receptors as drug targets--what are the challenges?Intense light-elicited upregulation of miR-21 facilitates glycolysis and cardioprotection through Per2-dependent mechanisms.GNAS gene variants affect β-blocker-related survival after coronary artery bypass grafting.Mechanism of the circadian clock in physiology.Calcineurin and its regulator, RCAN1, confer time-of-day changes in susceptibility of the heart to ischemia/reperfusion Period 2 is essential to maintain early endothelial progenitor cell function in vitro and angiogenesis after myocardial infarction in mice.Anesthetic cardioprotection: the role of adenosine.Purinergic signaling during inflammation.Adenosine signaling during acute and chronic disease states Extracellular nucleotide and nucleoside signaling in vascular and blood disease Circadian gene variants in cancer.Period2 deficiency blunts hypoxia-induced mobilization and function of endothelial progenitor cells.Advances in understanding the peripheral circadian clocks.Nucleotide signalling during inflammation Transcriptomic changes triggered by hypoxia: evidence for HIF-1α-independent, [Na+]i/[K+]i-mediated, excitation-transcription coupling.Targeting hypoxia signalling for the treatment of ischaemic and inflammatory diseases Influence of the cardiomyocyte circadian clock on cardiac physiology and pathophysiology.Anti-remodeling and anti-fibrotic effects of the neuregulin-1β glial growth factor 2 in a large animal model of heart failure Circadian rhythms in anesthesia and critical care medicine: potential importance of circadian disruptions Differential Tissue-Specific Function of Adora2b in Cardioprotection.Resolvin D1 and resolvin D2 govern local inflammatory tone in obese fat Health implications of disrupted circadian rhythms and the potential for daylight as therapy.Extracellular 2',3'-cAMP and 3',5'-cAMP stimulate proliferation of preglomerular vascular endothelial cells and renal epithelial cells Editorial: Health Impact and Management of a Disrupted Circadian Rhythm and Sleep in Critical Illnesses Metabolic preconditioning of mammalian cells: mimetic agents for hypoxia lack fidelity in promoting phosphorylation of pyruvate dehydrogenase Transcriptional control of adenosine signaling by hypoxia-inducible transcription factors during ischemic or inflammatory disease.Extracellular adenosine signaling in molecular medicine Adora2b adenosine receptor signaling protects during acute kidney injury via inhibition of neutrophil-dependent TNF-α release

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P2860

Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia.

http://www.wikidata.org/entity/Q34268301

description

2012 nî lūn-bûn

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2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2012 թվականի ապրիլին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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Adora2b-elicited Per2 stabiliz ...... ardial adaptation to ischemia.

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Adora2b-elicited Per2 stabiliz ...... ardial adaptation to ischemia.

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Adora2b-elicited Per2 stabiliz ...... ardial adaptation to ischemia.

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Adora2b-elicited Per2 stabiliz ...... ardial adaptation to ischemia.

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Adora2b-elicited Per2 stabiliz ...... ardial adaptation to ischemia.

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Adora2b-elicited Per2 stabiliz ...... ardial adaptation to ischemia.

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Adora2b-elicited Per2 stabiliz ...... ardial adaptation to ischemia.

@ast

Adora2b-elicited Per2 stabiliz ...... ardial adaptation to ischemia.

@en

Adora2b-elicited Per2 stabiliz ...... ardial adaptation to ischemia.

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Nature Medicine

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Adora2b-elicited Per2 stabiliz ...... ardial adaptation to ischemia.

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Christoph H Borchers

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Douglas J Kominsky

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Holger K Eltzschig

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Jun Han

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Katherine Hartmann

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Peter M Buttrick

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Sean P Colgan

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Stephanie Bonney

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Susan Reithel

http://www.w3.org/2001/XMLSchema#string

Tobias Eckle

http://www.w3.org/2001/XMLSchema#string

P2860

Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1

PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues.

Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: role of ectonucleotidases and adenosine A2B receptors

Crucial role for ecto-5'-nucleotidase (CD73) in vascular leakage during hypoxia.

Coordination of circadian timing in mammals

Posttranslational mechanisms regulate the mammalian circadian clock.

PER2 controls lipid metabolism by direct regulation of PPARγ

Mutation of the circadian clock gene Per2 alters vascular endothelial function

The failing heart--an engine out of fuel

The mammalian circadian timing system: organization and coordination of central and peripheral clocks

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774-782

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10.1038/NM.2728

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5

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18

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Michel Mittelbronn

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2012-04-15T00:00:00Z

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224038274

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22504483

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metabolic adaptation

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3378044

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