Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene.
about
Transthyretin and the brain re-visited: is neuronal synthesis of transthyretin protective in Alzheimer's disease?Lifestyle-related factors in predementia and dementia syndromesVitamin A and Alzheimer's diseaseTREM2 Variants in Alzheimer's DiseaseThe genetic epidemiology of neurodegenerative disease.Autosomal recessive hypercholesterolemia protein interacts with and regulates the cell surface level of Alzheimer's amyloid beta precursor proteinThe familial dementia BRI2 gene binds the Alzheimer gene amyloid-beta precursor protein and inhibits amyloid-beta productionHuntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzymeInteraction between amyloid precursor protein and presenilins in mammalian cells: implications for the pathogenesis of Alzheimer diseaseGeneration of anti-apoptotic presenilin-2 polypeptides by alternative transcription, proteolysis, and caspase-3 cleavageThe presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid beta protein ending at the 42nd (or 43rd) residueGenetic aspects of Alzheimer diseaseEnhancing CNS repair in neurological disease: challenges arising from neurodegeneration and rewiring of the networkThe neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer diseaseInteraction of presenilins with the filamin family of actin-binding proteinsA novel mechanism for the regulation of amyloid precursor protein metabolismPhosphorylation of presenilin-2 regulates its cleavage by caspases and retards progression of apoptosisWhen loss is gain: reduced presenilin proteolytic function leads to increased Abeta42/Abeta40. Talking Point on the role of presenilin mutations in Alzheimer diseaseThe presenilinslin-12 Notch functions in the adult nervous system of C. elegans.Inactivation of presenilins causes pre-synaptic impairment prior to post-synaptic dysfunctionMolecular Mechanisms in the Pathogenesis of Alzheimer's disease and Tauopathies-Prion-Like Seeded Aggregation and PhosphorylationMetals and Neuronal Metal Binding Proteins Implicated in Alzheimer's DiseaseTREM2 in CNS homeostasis and neurodegenerative diseaseMutations in presenilin 2 and its implications in Alzheimer's disease and other dementia-associated disordersCaenorhabditis elegans as a model organism to study APP functionBehavioral assays with mouse models of Alzheimer's disease: practical considerations and guidelines.Epidemiology of Alzheimer diseasePreclinical Alzheimer disease: identification of cases at risk among cognitively intact older individualsToward the structure of presenilin/γ-secretase and presenilin homologsLate-Onset Alzheimer's Disease Genes and the Potentially Implicated PathwaysRoles of vascular and metabolic components in cognitive dysfunction of Alzheimer disease: short- and long-term modification by non-genetic risk factorsStructural biology of presenilin 1 complexesThe genetics of Alzheimer diseaseSelf-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer's Disease PhenotypesRab GTPases, membrane trafficking and diseasesDo Microglia Default on Network Maintenance in Alzheimer's Disease?Stepping back to move forward: a current review of iPSCs in the fight against Alzheimer's diseaseGenetic variants associated with neurodegenerative Alzheimer disease in natural modelsCurrent and future implications of basic and translational research on amyloid-β peptide production and removal pathways
P2860
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P2860
Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene.
description
1995 nî lūn-bûn
@nan
1995 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Familial Alzheimer's disease i ...... zheimer's disease type 3 gene.
@ast
Familial Alzheimer's disease i ...... zheimer's disease type 3 gene.
@en
Familial Alzheimer's disease i ...... zheimer's disease type 3 gene.
@nl
type
label
Familial Alzheimer's disease i ...... zheimer's disease type 3 gene.
@ast
Familial Alzheimer's disease i ...... zheimer's disease type 3 gene.
@en
Familial Alzheimer's disease i ...... zheimer's disease type 3 gene.
@nl
prefLabel
Familial Alzheimer's disease i ...... zheimer's disease type 3 gene.
@ast
Familial Alzheimer's disease i ...... zheimer's disease type 3 gene.
@en
Familial Alzheimer's disease i ...... zheimer's disease type 3 gene.
@nl
P2093
P356
P1433
P1476
Familial Alzheimer's disease i ...... zheimer's disease type 3 gene.
@en
P2093
E A Rogaeva
E I Rogaev
G Levesque
R Sherrington
P2888
P304
P356
10.1038/376775A0
P407
P577
1995-08-01T00:00:00Z
P6179
1027907322