Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors.
about
Etiology of cardiovascular disease in patients with schizophrenia: current perspectivesAll the world's a (clinical) stage: rethinking bipolar disorder from a longitudinal perspectiveModeling a model: Mouse genetics, 22q11.2 Deletion Syndrome, and disorders of cortical circuit developmentWinner's Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level DataPathophysiologic relationship between Alzheimer's disease, cerebrovascular disease, and cardiovascular risk: A review and synthesisDeveloping and evaluating polygenic risk prediction models for stratified disease prevention.New statistical approaches exploit the polygenic architecture of schizophrenia--implications for the underlying neurobiology.Sparse models for correlative and integrative analysis of imaging and genetic dataGenetic Markers of Human Evolution Are Enriched in Schizophrenia.Increased cardiometabolic dysfunction in first-degree relatives of patients with psychotic disordersPatterns of physical co-/multi-morbidity among patients with serious mental illness: a London borough-based cross-sectional study.Bayesian semiparametric copula estimation with application to psychiatric geneticsShared common variants in prostate cancer and blood lipids.A sequence variant in human KALRN impairs protein function and coincides with reduced cortical thickness.Increased mortality in schizophrenia due to cardiovascular disease - a non-systematic review of epidemiology, possible causes, and interventions.Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate.Circadian rhythms, Wnt/beta-catenin pathway and PPAR alpha/gamma profiles in diseases with primary or secondary cardiac dysfunction.Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease.Integrative analysis of gene-environment interactions under a multi-response partially linear varying coefficient modelIdentifying Novel Gene Variants in Coronary Artery Disease and Shared Genes With Several Cardiovascular Risk FactorsShared genetic risk between corticobasal degeneration, progressive supranuclear palsy, and frontotemporal dementia.Adjusting for heritable covariates can bias effect estimates in genome-wide association studiesSomatic diseases and conditions before the first diagnosis of schizophrenia: a nationwide population-based cohort study in more than 900 000 individualsGenetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci.Regulatory and coding genome regions are enriched for trait associated variants in dairy and beef cattle.GPA: a statistical approach to prioritizing GWAS results by integrating pleiotropy and annotationRetinal microvessels reflect familial vulnerability to psychotic symptoms: A comparison of twins discordant for psychotic symptoms and controls.Genome-wide gene pathway analysis of psychotic illness symptom dimensions based on a new schizophrenia-specific model of the OPCRITAbundant genetic overlap between blood lipids and immune-mediated diseases indicates shared molecular genetic mechanisms.Protocol for CHANGE: a randomized clinical trial assessing lifestyle coaching plus care coordination versus care coordination alone versus treatment as usual to reduce risks of cardiovascular disease in adults with schizophrenia and abdominal obesitGenome-Wide Scan Informed by Age-Related Disease Identifies Loci for Exceptional Human LongevityGenetic Sharing with Cardiovascular Disease Risk Factors and Diabetes Reveals Novel Bone Mineral Density Loci.Leveraging Genomic Annotations and Pleiotropic Enrichment for Improved Replication Rates in Schizophrenia GWAS.Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locusLipid profiles in schizophrenia associated with clinical traits: a five year follow-up study.Systematic Integration of Brain eQTL and GWAS Identifies ZNF323 as a Novel Schizophrenia Risk Gene and Suggests Recent Positive Selection Based on Compensatory Advantage on Pulmonary Function.Pervasive pleiotropy between psychiatric disorders and immune disorders revealed by integrative analysis of multiple GWAS.Probing the Association between Early Evolutionary Markers and Schizophrenia.graph-GPA: A graphical model for prioritizing GWAS results and investigating pleiotropic architecture.Recent Positive Selection Drives the Expansion of a Schizophrenia Risk Nonsynonymous Variant at SLC39A8 in Europeans
P2860
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P2860
Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors.
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Improved detection of common v ...... vascular-disease risk factors.
@ast
Improved detection of common v ...... vascular-disease risk factors.
@en
Improved detection of common v ...... vascular-disease risk factors.
@nl
type
label
Improved detection of common v ...... vascular-disease risk factors.
@ast
Improved detection of common v ...... vascular-disease risk factors.
@en
Improved detection of common v ...... vascular-disease risk factors.
@nl
prefLabel
Improved detection of common v ...... vascular-disease risk factors.
@ast
Improved detection of common v ...... vascular-disease risk factors.
@en
Improved detection of common v ...... vascular-disease risk factors.
@nl
P2093
P2860
P50
P1476
Improved detection of common v ...... vascular-disease risk factors.
@en
P2093
Andrew J Schork
Andrew P Morris
Diabetes Genetics Replication and Meta-analysis Consortium
International Consortium for Blood Pressure GWAS
J Cooper Roddey
Linda K McEvoy
Psychiatric Genomics Consortium Schizophrenia Working Group
Rahul S Desikan
Wesley K Thompson
P2860
P304
P356
10.1016/J.AJHG.2013.01.001
P407
P50
P577
2013-01-31T00:00:00Z