Extracellular NAD+ shapes the Foxp3+ regulatory T cell compartment through the ART2-P2X7 pathway - sprookjes - yvandenbroek - TriplyDB

Extracellular NAD+ shapes the Foxp3+ regulatory T cell compartment through the ART2-P2X7 pathway

Extracellular NAD+ shapes the Foxp3+ regulatory T cell compartment through the ART2-P2X7 pathway

http://www.wikidata.org/entity/Q34340613

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NAD⁺-Metabolizing Ectoenzymes in Remodeling Tumor-Host Interactions: The Human Myeloma Model Tregs in infection and vaccinology: heroes or traitors?The art of blocking ADP-ribosyltransferases (ARTs): nanobodies as experimental and therapeutic tools to block mammalian and toxin ARTs Anti-CD38 antibody therapy: windows of opportunity yielded by the functional characteristics of the target molecule NAD(+) regulates Treg cell fate and promotes allograft survival via a systemic IL-10 production that is CD4(+) CD25(+) Foxp3(+) T cells independent.Immunometabolism of regulatory T cells The PI3K p110δ regulates expression of CD38 on regulatory T cells Meat and Nicotinamide: A Causal Role in Human Evolution, History, and Demographics.Meat Intake and the Dose of Vitamin B3 - Nicotinamide: Cause of the Causes of Disease Transitions, Health Divides, and Health Futures?Compartmentation of NAD+-dependent signalling.Differential modulation of ATP-induced P2X7-associated permeabilities to cations and anions of macrophages by infection with Leishmania amazonensis.Immunological tolerance to muscle autoantigens involves peripheral deletion of autoreactive CD8+ T cells ATP synthesis and storage.Alternative splicing of the N-terminal cytosolic and transmembrane domains of P2X7 controls gating of the ion channel by ADP-ribosylation.NAD+ protects against EAE by regulating CD4+ T-cell differentiation Loss of P2X7 receptor plasma membrane expression and function in pathogenic B220+ double-negative T lymphocytes of autoimmune MRL/lpr mice.Testing the role of P2X7 receptors in the development of type 1 diabetes in nonobese diabetic mice Adipocytokine profile, cytokine levels and foxp3 expression in multiple sclerosis: a possible link to susceptibility and clinical course of disease.Activation and regulation of purinergic P2X receptor channels Progesterone promotes differentiation of human cord blood fetal T cells into T regulatory cells but suppresses their differentiation into Th17 cells.CD38 is expressed on inflammatory cells of the intestine and promotes intestinal inflammation P2X7 on Mouse T Cells: One Channel, Many Functions Unstable FoxP3+ T regulatory cells in NZW mice.Oral-tolerization Prevents Immune Responses and Improves Transgene Persistence Following Gene Transfer Mediated by Adeno-associated Viral Vector.CD38 and chronic lymphocytic leukemia: a decade later.Nutrient and Metabolic Sensing in T Cell Responses.NAD+-metabolizing ecto-enzymes shape tumor-host interactions: the chronic lymphocytic leukemia model.Danger signals activating innate immunity in graft-versus-host disease.Ectonucleotidases as regulators of purinergic signaling in thrombosis, inflammation, and immunity.Making sense of regulatory T cell suppressive function.Ectoenzymes controlling leukocyte traffic.Beyond DNA repair, the immunological role of PARP-1 and its siblings.Purinergic signalling and immune cells.In vivo near-infrared fluorescence targeting of T cells: comparison of nanobodies and conventional monoclonal antibodies.Metabolic Cooperation and Competition in the Tumor Microenvironment: Implications for Therapy.Purinergic signalling links mechanical breath profile and alveolar mechanics with the pro-inflammatory innate immune response causing ventilation-induced lung injury.Possible role of hemichannels in cancer.Does the PI3K pathway promote or antagonize regulatory T cell development and function?Tuning IL-2 signaling by ADP-ribosylation of CD25.Roles and Modalities of Ectonucleotidases in Remodeling the Multiple Myeloma Niche.

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P2860

Extracellular NAD+ shapes the Foxp3+ regulatory T cell compartment through the ART2-P2X7 pathway

http://www.wikidata.org/entity/Q34340613

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年學術文章

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Extracellular NAD+ shapes the ...... through the ART2-P2X7 pathway

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Extracellular NAD+ shapes the ...... through the ART2-P2X7 pathway

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Extracellular NAD+ shapes the ...... through the ART2-P2X7 pathway

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Extracellular NAD+ shapes the ...... through the ART2-P2X7 pathway

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Extracellular NAD+ shapes the ...... through the ART2-P2X7 pathway

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Extracellular NAD+ shapes the ...... through the ART2-P2X7 pathway

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Extracellular NAD+ shapes the ...... through the ART2-P2X7 pathway

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Journal of Experimental Medicine

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Extracellular NAD+ shapes the ...... through the ART2-P2X7 pathway

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Björn Rissiek

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Friedrich Haag

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Jochen Huehn

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Katjana Klages

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Michel Seman

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Olivier Boyer

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Sahil Adriouch

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Sandra Hubert

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Tim Sparwasser

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P2860

Control of regulatory T cell development by the transcription factor Foxp3

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

Cyclic ADP-ribose production by CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is required for bacterial clearance in vivo

The amount of scurfin protein determines peripheral T cell number and responsiveness

Altered cytokine production in mice lacking P2X(7) receptors

High sensitivity of CD4+CD25+ regulatory T cells to extracellular metabolites nicotinamide adenine dinucleotide and ATP: a role for P2X7 receptors

Nucleotide receptors: an emerging family of regulatory molecules in blood cells

Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

Efficient cancer therapy with a nanobody-based conjugate.

A recombinant heavy chain antibody approach blocks ART2 mediated deletion of an iNKT cell population that upon activation inhibits autoimmune diabetes

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2561-2568

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10.1084/JEM.20091154

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12

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207

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Friedrich Koch-Nolte

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2010-10-25T00:00:00Z

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47544479

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20975043

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