Transport approaches to the biopharmaceutical design of oral drug delivery systems: prediction of intestinal absorption.
about
Drug Delivery Approaches in Addressing Clinical Pharmacology-Related Issues: Opportunities and ChallengesThe use of modeling tools to drive efficient oral product designTranslating Human Effective Jejunal Intestinal Permeability to Surface-Dependent Intrinsic Permeability: a Pragmatic Method for a More Mechanistic Prediction of Regional Oral Drug Absorption.Utility of physiologically based absorption modeling in implementing Quality by Design in drug developmentIntegrating in vitro ADMET data through generic physiologically based pharmacokinetic models.Combinatorial informatics in the post-genomics ERA.Mechanistic approaches to predicting oral drug absorption.Prediction of modified release pharmacokinetics and pharmacodynamics from in vitro, immediate release, and intravenous data.Practical anticipation of human efficacious doses and pharmacokinetics using in vitro and preclinical in vivo data.Understanding peroral absorption: regulatory aspects and contemporary approaches to tackling solubility and permeability hurdlesPermeation of aromatic carboxylic acids across lipid bilayers: the pH-partition hypothesis revisitedA physiologically based pharmacokinetic model of the minipig: data compilation and model implementation.A mechanistic approach to understanding the factors affecting drug absorption: a review of fundamentals.Synthesis and characterization of a new Peptide prodrug of glucosamine with enhanced gut permeability.Mathematical Models to Explore Potential Effects of Supersaturation and Precipitation on Oral Bioavailability of Poorly Soluble Drugs.Pollen grains for oral vaccinationPrediction of human pharmacokinetics--gastrointestinal absorption.Predicting pharmacokinetics of drugs using physiologically based modeling--application to food effectsPopulation-based mechanistic prediction of oral drug absorptionUnderstanding the effect of API properties on bioavailability through absorption modeling.Physiologically based pharmacokinetics (PBPK).Prediction of solubility and permeability class membership: provisional BCS classification of the world's top oral drugsApplication of physiologically based absorption modeling to formulation development of a low solubility, low permeability weak base: mechanistic investigation of food effect.An update on computational oral absorption simulation.The solubility-permeability interplay and its implications in formulation design and development for poorly soluble drugs.Absolute abundance and function of intestinal drug transporters: a prerequisite for fully mechanistic in vitro-in vivo extrapolation of oral drug absorption.Experimental models for predicting drug absorption and metabolism.In vitro-in vivo extrapolation (IVIVE) for predicting human intestinal absorption and first-pass elimination of drugs: principles and applications.In vitro oral drug permeation models: the importance of taking physiological and physico-chemical factors into consideration.Lipid-associated oral delivery: Mechanisms and analysis of oral absorption enhancement.An introduction to physiologically-based pharmacokinetic models.Application of a Bayesian approach to physiological modelling of mavoglurant population pharmacokinetics.In vitro-in vivo correlation for gliclazide immediate-release tablets based on mechanistic absorption simulationCell-based multiscale computational modeling of small molecule absorption and retention in the lungs.The fraction dose absorbed, in humans, and high jejunal human permeability relationship.Assessment of intestinal absorption of total flavones of Hippophae rhamnoides L. in rat using in situ absorption models.Meta-analysis of oro-cecal transit time in fasting subjects.The effect of enzyme inhibitor and absorption site following [D-ala2, D-leu5]enkephalin oral administration in rats.A highly automated assay for determining the aqueous equilibrium solubility of drug discovery compounds.Understanding pharmacokinetic food effects using molecular dynamics simulation coupled with physiologically based pharmacokinetic modeling.
P2860
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P2860
Transport approaches to the biopharmaceutical design of oral drug delivery systems: prediction of intestinal absorption.
description
1996 nî lūn-bûn
@nan
1996 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Transport approaches to the bi ...... tion of intestinal absorption.
@ast
Transport approaches to the bi ...... tion of intestinal absorption.
@en
Transport approaches to the bi ...... tion of intestinal absorption.
@nl
type
label
Transport approaches to the bi ...... tion of intestinal absorption.
@ast
Transport approaches to the bi ...... tion of intestinal absorption.
@en
Transport approaches to the bi ...... tion of intestinal absorption.
@nl
prefLabel
Transport approaches to the bi ...... tion of intestinal absorption.
@ast
Transport approaches to the bi ...... tion of intestinal absorption.
@en
Transport approaches to the bi ...... tion of intestinal absorption.
@nl
P2093
P1476
Transport approaches to the bi ...... tion of intestinal absorption.
@en
P2093
P304
P356
10.1016/0169-409X(96)00009-9
P407
P577
1996-06-01T00:00:00Z