Mutant mice lacking the gamma isoform of protein kinase C show decreased behavioral actions of ethanol and altered function of gamma-aminobutyrate type A receptors.
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Alcoholism: A Systems Approach From Molecular Physiology to Addictive BehaviorNeuropharmacology of alcohol addictionPotentiation of Gamma Aminobutyric Acid Receptors (GABAAR) by Ethanol: How Are Inhibitory Receptors Affected?Increased response to morphine in mice lacking protein kinase C epsilonEthanol opens G-protein-activated inwardly rectifying K+ channelsPrion protein is a key determinant of alcohol sensitivity through the modulation of N-methyl-D-aspartate receptor (NMDAR) activityPKC epsilon has an alcohol-binding site in its second cysteine-rich regulatory domainMolecular and behavioral characterization of adolescent protein kinase C following high dose ethanol exposure.Opposite actions of alcohol on tonic GABA(A) receptor currents mediated by nNOS and PKC activity.The role of GABA(A) receptors in the acute and chronic effects of ethanol: a decade of progressLow dose acute alcohol effects on GABA A receptor subtypesProtein kinase C deficiency-induced alcohol insensitivity and underlying cellular targets in Drosophila.Acute ethanol administration rapidly increases phosphorylation of conventional protein kinase C in specific mammalian brain regions in vivoGABAA receptor regulation of voluntary ethanol drinking requires PKCepsilonEthanol reduces GABAA alpha1 subunit receptor surface expression by a protein kinase Cgamma-dependent mechanism in cultured cerebral cortical neurons.Normal acute behavioral responses to moderate/high dose ethanol in GABAA receptor alpha 4 subunit knockout mice.How adaptation of the brain to alcohol leads to dependence: a pharmacological perspective.Association of protein kinase C with GABA(A) receptors containing alpha1 and alpha4 subunits in the cerebral cortex: selective effects of chronic ethanol consumption.Predictors of high ethanol consumption in RIIbeta knock-out mice: assessment of anxiety and ethanol-induced sedation.Behavioral effects of ethanol in cerebellum are age dependent: potential system and molecular mechanismsEthanol, gamma-aminobutyrate type A receptors, and protein kinase C phosphorylation.Age-related effects of alcohol from adolescent, adult, and aged populations using human and animal models.Protein kinases and addiction.Protein kinase C isozymes as regulators of sensitivity to and self-administration of drugs of abuse-studies with genetically modified mice.Decreased anxiety-like behavior, reduced stress hormones, and neurosteroid supersensitivity in mice lacking protein kinase Cepsilon.Type 1 equilibrative nucleoside transporter regulates ethanol drinking through accumbal N-methyl-D-aspartate receptor signalingThe role of GABAA receptors in mediating the effects of alcohol in the central nervous system.Regulation of 5-HT2A/C receptors and DOI-induced behaviors by protein kinase Cgamma.Genetic study of alcoholism and novel gene expression in the alcoholic brain.Microarray analysis identifies cerebellar genes sensitive to chronic ethanol treatment in PKCgamma miceAspects of the homeostaic plasticity of GABAA receptor-mediated inhibition.A conceptualization of integrated actions of ethanol contributing to its GABAmimetic profile: a commentary.The "ups and downs" of signaling cascades in addiction.Regulation of Extrasynaptic GABAA α4 Receptors by Ethanol-Induced Protein Kinase A, but Not Protein Kinase C Activation in Cultured Rat Cerebral Cortical NeuronsCardioprotection from ischemia by a brief exposure to physiological levels of ethanol: role of epsilon protein kinase C.Transcriptome analysis of Inbred Long Sleep and Inbred Short Sleep miceModulation of GABAA receptors in cerebellar granule neurons by ethanol: a review of genetic and electrophysiological studies.MeCP2 regulates ethanol sensitivity and intake.Protein kinase Cdelta regulates ethanol intoxication and enhancement of GABA-stimulated tonic current.The molecular basis of tolerance.
P2860
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P2860
Mutant mice lacking the gamma isoform of protein kinase C show decreased behavioral actions of ethanol and altered function of gamma-aminobutyrate type A receptors.
description
1995 nî lūn-bûn
@nan
1995 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Mutant mice lacking the gamma ...... minobutyrate type A receptors.
@ast
Mutant mice lacking the gamma ...... minobutyrate type A receptors.
@en
Mutant mice lacking the gamma ...... minobutyrate type A receptors.
@nl
type
label
Mutant mice lacking the gamma ...... minobutyrate type A receptors.
@ast
Mutant mice lacking the gamma ...... minobutyrate type A receptors.
@en
Mutant mice lacking the gamma ...... minobutyrate type A receptors.
@nl
prefLabel
Mutant mice lacking the gamma ...... minobutyrate type A receptors.
@ast
Mutant mice lacking the gamma ...... minobutyrate type A receptors.
@en
Mutant mice lacking the gamma ...... minobutyrate type A receptors.
@nl
P2093
P2860
P356
P1476
Mutant mice lacking the gamma ...... minobutyrate type A receptors.
@en
P2093
A Abeliovich
J M Wehner
R A Harris
S J McQuilkin
S Tonegawa
P2860
P304
P356
10.1073/PNAS.92.9.3658
P407
P577
1995-04-01T00:00:00Z