Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants
about
Genome-edited human stem cell-derived beta cells: a powerful tool for drilling down on type 2 diabetes GWAS biologyAutoimmune diseases - connecting risk alleles with molecular traits of the immune system.Decoding the non-coding genome: elucidating genetic risk outside the coding genomeEpigenetic Codes Programing Class Switch RecombinationTranscriptional enhancers: functional insights and role in human diseaseThe epigenome, 4D nucleome and next-generation neuropsychiatric pharmacogenomicsExploiting genomics and natural genetic variation to decode macrophage enhancersSMC complexes link gene expression and genome architectureSuper-enhancers: Asset management in immune cell genomesInvestigating the transcriptional control of cardiovascular developmentMechanisms Underlying the Selection and Function of Macrophage-Specific EnhancersThe selection and function of cell type-specific enhancersThe mechanisms behind the therapeutic activity of BET bromodomain inhibitionConvergent transcription at intragenic super-enhancers targets AID-initiated genomic instabilityThe Effects of Sequence Variation on Genome-wide NRF2 Binding--New Target Genes and Regulatory SNPsdbSUPER: a database of super-enhancers in mouse and human genomeBCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesisIntegrated metabolic modelling reveals cell-type specific epigenetic control points of the macrophage metabolic networkGREGOR: evaluating global enrichment of trait-associated variants in epigenomic features using a systematic, data-driven approachGenetic and epigenetic fine mapping of causal autoimmune disease variantsEpigenomic comparison reveals activation of "seed" enhancers during transition from naive to primed pluripotencyThe genetic architecture of type 2 diabetesIslet biology, the CDKN2A/B locus and type 2 diabetes risk.Trans-ethnic Fine Mapping Highlights Kidney-Function Genes Linked to Salt Sensitivity.Joint analysis of functional genomic data and genome-wide association studies of 18 human traits.Transcript Expression Data from Human Islets Links Regulatory Signals from Genome-Wide Association Studies for Type 2 Diabetes and Glycemic Traits to Their Downstream Effectors.The Pancreatic Islet Regulome Browser.Laying a solid foundation for Manhattan--'setting the functional basis for the post-GWAS era'.Platelet function is modified by common sequence variation in megakaryocyte super enhancersPromiscuous MYC locus rearrangements hijack enhancers but mostly super-enhancers to dysregulate MYC expression in multiple myeloma.Enhancers as non-coding RNA transcription units: recent insights and future perspectives.Identification of a regulatory variant that binds FOXA1 and FOXA2 at the CDC123/CAMK1D type 2 diabetes GWAS locus.Enhancing the understanding of asthma.NOTCH1-RBPJ complexes drive target gene expression through dynamic interactions with superenhancers.Global transcriptome analysis and enhancer landscape of human primary T follicular helper and T effector lymphocytes.Super-enhancers delineate disease-associated regulatory nodes in T cells.Genome-wide associations between genetic and epigenetic variation influence mRNA expression and insulin secretion in human pancreatic islets.Convergence of developmental and oncogenic signaling pathways at transcriptional super-enhancers.Transcription factor co-occupied regions in the murine genome constitute T-helper-cell subtype-specific enhancers.The pancreatic β cell: recent insights from human genetics.
P2860
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P2860
Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants
description
2013 nî lūn-bûn
@nan
2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Chromatin stretch enhancer sta ...... or human disease risk variants
@ast
Chromatin stretch enhancer sta ...... or human disease risk variants
@en
Chromatin stretch enhancer sta ...... or human disease risk variants
@nl
type
label
Chromatin stretch enhancer sta ...... or human disease risk variants
@ast
Chromatin stretch enhancer sta ...... or human disease risk variants
@en
Chromatin stretch enhancer sta ...... or human disease risk variants
@nl
prefLabel
Chromatin stretch enhancer sta ...... or human disease risk variants
@ast
Chromatin stretch enhancer sta ...... or human disease risk variants
@en
Chromatin stretch enhancer sta ...... or human disease risk variants
@nl
P2093
P2860
P50
P356
P1476
Chromatin stretch enhancer sta ...... or human disease risk variants
@en
P2093
D Leland Taylor
Jennifer A Akiyama
Jose Miguel Orozco
Kelly Lammerts van Bueren
Len A Pennacchio
Michael L Stitzel
Michael R Erdos
NISC Comparative Sequencing Program Authors
National Institutes of Health ...... ive Sequencing Program Authors
Peter S Chines
P2860
P304
17921-17926
P356
10.1073/PNAS.1317023110
P407
P577
2013-10-14T00:00:00Z