Possible association between autism and variants in the brain-expressed tryptophan hydroxylase gene (TPH2). - sprookjes - yvandenbroek - TriplyDB

Possible association between autism and variants in the brain-expressed tryptophan hydroxylase gene (TPH2).

Possible association between autism and variants in the brain-expressed tryptophan hydroxylase gene (TPH2).

http://www.wikidata.org/entity/Q34403081

about

Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants.Statistical distribution of blood serotonin as a predictor of early autistic brain abnormalities.Neuroimaging endophenotypes in autism spectrum disorder Acute dietary tryptophan manipulation differentially alters social behavior, brain serotonin and plasma corticosterone in three inbred mouse strains Mice genetically depleted of brain serotonin display social impairments, communication deficits and repetitive behaviors: possible relevance to autism The disruption of Celf6, a gene identified by translational profiling of serotonergic neurons, results in autism-related behaviors.Reduced isolation-induced pup ultrasonic communication in mouse pups lacking brain serotonin.The serotonergic system: its role in pathogenesis and early developmental treatment of autism.Case-control and family-based association studies of candidate genes in autistic disorder and its endophenotypes: TPH2 and GLO1.Tryptophan-hydroxylase 2 haplotype association with borderline personality disorder and aggression in a sample of patients with personality disorders and healthy controls.The neurobiology of autism.TPH2 and TPH1: association of variants and interactions with heroin addiction.Glutamate transporter gene (SLC1A1) single nucleotide polymorphism (rs301430) and repetitive behaviors and anxiety in children with autism spectrum disorder.Tryptophan research in panic disorder Serotonin transporter gene polymorphisms and hyperserotonemia in autistic disorder.TPH2 G/T polymorphism is associated with hyperphagia, IQ, and internalizing problems in Prader-Willi syndrome.Neonatal serotonin depletion alters behavioral responses to spatial change and novelty.Glucocorticoid modulation of tryptophan hydroxylase-2 protein in raphe nuclei and 5-hydroxytryptophan concentrations in frontal cortex of C57/Bl6 mice.Parent-of-origin effects of the serotonin transporter gene associated with autism.Functional polymorphisms of the brain serotonin synthesizing enzyme tryptophan hydroxylase-2.Genetic origins of social networks in rhesus macaques What do we know about the serotonergic genetic heterogeneity in attention-deficit/hyperactivity and autistic disorders?Neuroethology of primate social behavior Autism spectrum disorder causes, mechanisms, and treatments: focus on neuronal synapses.Autism spectrum and obsessive-compulsive disorders: OC behaviors, phenotypes and genetics.5'-Untranslated region of the tryptophan hydroxylase-2 gene harbors an asymmetric bidirectional promoter but not internal ribosome entry site in vitro.Functional characterization of the human TPH2 5' regulatory region: untranslated region and polymorphisms modulate gene expression in vitro.Rhesus monkey tryptophan hydroxylase-2 coding region haplotypes affect mRNA stability.Population-specific functional variant of the TPH2 gene 2755C>A polymorphism contributes risk association to major depression and anxiety in Chinese peripartum women.Functional gene variants of the serotonin-synthesizing enzyme tryptophan hydroxylase 2 in migraine.Tryptophan hydroxylase-2 gene polymorphisms in rhesus monkeys: association with hypothalamic-pituitary-adrenal axis function and in vitro gene expression.

P2860

Q21144229-FAD63FF5-9328-42C0-97D9-8D94A1D0CA84 Q24811773-CDBACFE0-BDE1-415B-A38A-12452EB3F4FA Q26800176-9BD030D4-418B-4519-9434-D87DC4346A88 Q28384969-5056E521-AB79-4AE2-85C4-6AFA10B1D988 Q28390641-EE7DF56D-6BCA-4115-A23B-37D016C79E50 Q28508280-62C83BFE-C8C4-4470-B0BC-B7551853948E Q30413780-B8C627E1-183F-4724-A124-D29F2C45D19B Q30484882-E2017BB6-CCF6-4A1F-AAFA-F8CC7313FFE2 Q33277435-F6E4A9EC-A14F-43DC-9303-9BFE53881FE3 Q34203722-C7ACB8C3-1556-4B98-8355-BF58D0A5C68D Q34699035-8B6C9D14-B37F-40EB-97F9-51559A627BE6 Q34734000-21C033D9-7BCC-4DDD-BA9B-9604DA09CCEE Q35142445-E05D7AC3-F3DC-4E97-AD69-EA0C2EEA2F86 Q35366543-7142BDBD-415F-404D-B29A-C3EB230A5BA3 Q35851031-B226D6C7-0559-4963-80D3-35BE87C301C0 Q35963550-FAAEDA8D-EC5C-4B7A-BEB8-F2602C541987 Q35987563-97120E42-9E89-4911-AF5C-2C9933331246 Q36083327-C5FEAA09-ACBD-46FF-B52D-2B60D73420E3 Q36224018-E55893C4-ADFA-4EAD-BCE2-53CE36E9AB25 Q36353771-E3B6E41D-09B6-4E0F-AB67-D9208576052F Q36518973-00BFDEB5-9090-48B9-928E-E12876A90EAC Q36881183-A4E18C08-EC67-4A69-8703-8E5974BA9D87 Q36949662-D731B9DB-B304-46DB-A42E-2911B7800BB4 Q37068738-B7A1899E-C7E2-46D1-AE43-BB60F916328A Q37661412-A968BF8D-8974-486D-B729-F70CB080E11E Q39864341-0873C4F5-D749-4D53-BF44-ABB5723981D8 Q41873578-B8E3B6E7-819F-4C15-A2FA-E8955FF27555 Q43178933-895BA498-1A85-4F68-ADC9-FFD7EBEE67B7 Q45934609-79BBFA0F-2C9E-4A89-BEAB-34743766901C Q46015625-94097319-38CF-4A48-82FD-6DA23C05201E Q48469199-4DAA079E-DA3C-4DE6-96A9-1E67D6223DA3

P2860

Possible association between autism and variants in the brain-expressed tryptophan hydroxylase gene (TPH2).

http://www.wikidata.org/entity/Q34403081

description

2005 nî lūn-bûn

@nan

2005 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2005年の論文

@ja

2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

Possible association between a ...... ophan hydroxylase gene (TPH2).

@ast

Possible association between a ...... ophan hydroxylase gene (TPH2).

@en

Possible association between a ...... ed tryptophan hydroxylase gene

@nl

type

label

Possible association between a ...... ophan hydroxylase gene (TPH2).

@ast

Possible association between a ...... ophan hydroxylase gene (TPH2).

@en

Possible association between a ...... ed tryptophan hydroxylase gene

@nl

prefLabel

Possible association between a ...... ophan hydroxylase gene (TPH2).

@ast

Possible association between a ...... ophan hydroxylase gene (TPH2).

@en

Possible association between a ...... ed tryptophan hydroxylase gene

@nl

P1433

Q34403081-EFBC51B6-2B20-4EE0-B3A7-AA4545865BB2

P1476

Q34403081-A288F38D-0622-4D1C-82C5-5D4E3098BE00

P2093

Q34403081-1C893813-663C-43BF-89CF-8A9FADF93EC9

Q34403081-3DD0B308-A7E6-4CAA-96C2-BF5B29973E7C

Q34403081-44726A27-91E9-487B-9128-CC3157316403

Q34403081-737CA8C9-4659-4D11-BD04-87591E5238C7

Q34403081-7D56F5D7-4A2A-4D80-9BE1-A92DABCFA73E

Q34403081-7DE48BEA-7836-46CE-BF63-DBA29C754884

Q34403081-B08DF3B4-060F-449A-878C-B74E98CA4F24

Q34403081-B2F2D314-F2FD-4515-86A8-6A0012EDFADC

Q34403081-BC4F8830-2F14-49D6-A787-7A270D5956BE

P2860

Q34403081-15034D0A-ECB7-4A43-B7F1-09B0B4C629EB

Q34403081-32429924-A7C3-4FA2-BC41-942544DBD3D0

P304

Q34403081-40DC146E-C6E2-46E7-A5C7-E4D476D0F2FF

P31

Q34403081-A07CCE16-F867-449D-A7EE-77A43D74C88B

P356

Q34403081-DC34B09C-B44F-4684-82EF-B57CD3DD3C32

P433

Q34403081-3288DC76-714F-45D1-934E-B22BDB29AB73

P478

Q34403081-8BAD99D1-0C5C-4730-A944-4C131A4EB1E6

P50

Q34403081-5CE440B1-F0FE-4E75-BA6B-3285F502553E

P577

Q34403081-50EDDC82-E25C-4BB1-A2E8-5FF614F8CEF3

P698

Q34403081-391F1C51-2236-4C98-96F0-4DCB776CC2A1

P921

Q34403081-E282F766-1E7A-429B-8BED-4F2AE4520799

P356

P1433

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

P1476

Possible association between a ...... tophan hydroxylase gene (TPH2)

@en

P2093

Agatino Battaglia

http://www.w3.org/2001/XMLSchema#string

Cindy Hamil

http://www.w3.org/2001/XMLSchema#string

Diane Dunn

http://www.w3.org/2001/XMLSchema#string

Janet Lainhart

http://www.w3.org/2001/XMLSchema#string

Judith Miller

http://www.w3.org/2001/XMLSchema#string

Mark F Leppert

http://www.w3.org/2001/XMLSchema#string

Raffaella Tancredi

http://www.w3.org/2001/XMLSchema#string

Robert Weiss

http://www.w3.org/2001/XMLSchema#string

William McMahon

http://www.w3.org/2001/XMLSchema#string

P2860

Effects of tryptophan depletion in drug-free adults with autistic disorder.

Autistic children and their first-degree relatives: relationships between serotonin and norepinephrine levels and intelligence.

P304

42-46

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1002/AJMG.B.30168

http://www.w3.org/2001/XMLSchema#string

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

135B

http://www.w3.org/2001/XMLSchema#string

P50

P577

2005-05-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

15768392

http://www.w3.org/2001/XMLSchema#string

P921