Hepatitis C virus NS2/3 processing is required for NS3 stability and viral RNA replication. - sprookjes - yvandenbroek - TriplyDB

Hepatitis C virus NS2/3 processing is required for NS3 stability and viral RNA replication.

Hepatitis C virus NS2/3 processing is required for NS3 stability and viral RNA replication.

http://www.wikidata.org/entity/Q34429108

about

Structures of hepatitis C virus nonstructural proteins required for replicase assembly and function NS3 protease from hepatitis C virus: biophysical studies on an intrinsically disordered protein domain Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimeras Compensatory Mutations in E1, p7, NS2, and NS3 Enhance Yields of Cell Culture-Infectious Intergenotypic Chimeric Hepatitis C Virus Hepatitis C Virus p7 and NS2 Proteins Are Essential for Production of Infectious Virus Discovery and Characterization of Substituted Diphenyl Heterocyclic Compounds as Potent and Selective Inhibitors of Hepatitis C Virus Replication NS3 Helicase Domains Involved in Infectious Intracellular Hepatitis C Virus Particle Assembly Structural and Functional Characterization of Nonstructural Protein 2 for Its Role in Hepatitis C Virus Assembly Hepatitis C virus NS2 is a protease stimulated by cofactor domains in NS3 trans-Complementation of an NS2 Defect in a Late Step in Hepatitis C Virus (HCV) Particle Assembly and Maturation Essential Role of Cyclophilin A for Hepatitis C Virus Replication and Virus Production and Possible Link to Polyprotein Cleavage Kinetics Naturally Occurring Hepatitis C Virus Subgenomic Deletion Mutants Replicate Efficiently in Huh-7 Cells and Are trans-Packaged In Vitro To Generate Infectious Defective Particles Determinants of the Hepatitis C Virus Nonstructural Protein 2 Protease Domain Required for Production of Infectious Virus Structural and Functional Studies of Nonstructural Protein 2 of the Hepatitis C Virus Reveal Its Key Role as Organizer of Virion Assembly Identification and characterization of the host protein DNAJC14 as a broadly active flavivirus replication modulator HD-PTP is a catalytically inactive tyrosine phosphatase due to a conserved divergence in its phosphatase domain.Rad51 Interacts with Non-structural 3 Protein of Hepatitis C Virus and Regulates Viral Production Novel nucleotide and amino acid covariation between the 5'UTR and the NS2/NS3 proteins of hepatitis C virus: bioinformatic and functional analyses.Targeting the non-structural proteins of hepatitis C virus: beyond hepatitis C virus protease and polymerase.The subcellular localization of the hepatitis C virus non-structural protein NS2 is regulated by an ion channel-independent function of the p7 protein Epoxide based inhibitors of the hepatitis C virus non-structural 2 autoprotease A conserved NS3 surface patch orchestrates NS2 protease stimulation, NS5A hyperphosphorylation and HCV genome replication.Identification of a lead like inhibitor of the hepatitis C virus non-structural NS2 autoprotease.Genetic and functional characterization of the N-terminal region of the hepatitis C virus NS2 protein Post-translational modifications of hepatitis C viral proteins and their biological significance.The Hepatitis C Virus Nonstructural Protein 2 (NS2): An Up-and-Coming Antiviral Drug Target.The ubiquitin-proteasome system in positive-strand RNA virus infection.Virion assembly and release.Ubiquitin-like protein modifiers and their potential for antiviral and anti-HCV therapy.Conformational stability of hepatitis C virus NS3 protease.NS2 proteases from hepatitis C virus and related hepaciviruses share composite active sites and previously unrecognized intrinsic proteolytic activities.

P2860

Q26991855-78E5A6E1-5042-482D-A3CC-7EE1907FAF41 Q27000813-4F47C971-F0AB-488F-B7C3-26AF13BA330C Q27473179-68D9F8C2-DF20-43F9-A983-8BA618694B8B Q27478033-8D0FAFDC-0667-4C09-970D-AA3C95F4F8E4 Q27481018-CAA33E56-B10E-432F-9BCA-373D5B213611 Q27485724-9B9926D5-083A-40CC-A63A-F06DD29AA73E Q27486581-1B4AF94F-DC24-4B80-87E7-AE339E7E6FAB Q27488261-B7E442F3-332F-4711-938C-7FC185B5C783 Q27488282-FA1D1821-E43A-4F7C-AF7D-596252CECEDD Q27488316-5213B09B-7CCA-4210-8BA9-9015768AA083 Q27489037-62833F27-E649-4B54-BF9F-0CFF669CCCC2 Q27489540-3DA6F02E-2C8E-40A4-8F6B-883E563417E0 Q27490479-109368FA-BC55-4534-82F5-E7F1250CE2C5 Q27666400-C7510DC1-33B6-4D7C-A562-EDD82D52F8B3 Q28476726-1ECB4DBC-64A5-444E-8369-1F6DD385A3BA Q33425933-518E4280-D025-48A6-94B5-9411425932C6 Q33875390-7B6190B9-6FBD-4CB4-B4D9-0AD261544988 Q34043316-8855F588-B1CC-4482-AA99-21EBA0E878E1 Q34620091-2CF4F5E3-C379-46B0-80B8-B24150D541CF Q35097566-3E9CD35B-42C5-499E-BB75-C2807DC7E95A Q35431032-7876581E-B04D-4B1F-B50D-E14113E1D34F Q35578182-C8229339-E3C3-46D1-9F1B-0AC0DA4CA5C0 Q35827684-1EAAE122-A3A9-4832-97D8-939AED321B59 Q36760201-C0A6DB36-2AF2-4E93-854C-360075FBF459 Q37408926-AE5EAF1D-CC93-4C98-8371-6BCFB8244F93 Q37945210-C4168834-CD2A-4871-94B8-4A993FAB8B03 Q38025341-F69BDF0B-ECF8-4626-B403-ABFC1380EB52 Q38086754-05F29D3A-37F5-4A17-A1F3-4F468BDDC684 Q38115330-B6A9A764-9C67-4916-9689-7C7F2063F5FD Q41152906-A9EA808A-2593-43D8-9703-8AF29089CDB3 Q50133220-175AF7FA-6455-426D-AEA8-A9354BBB82ED

P2860

Hepatitis C virus NS2/3 processing is required for NS3 stability and viral RNA replication.

http://www.wikidata.org/entity/Q34429108

description

2005 nî lūn-bûn

@nan

2005 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2005年の論文

@ja

2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

Hepatitis C virus NS2/3 proces ...... ity and viral RNA replication.

@ast

Hepatitis C virus NS2/3 proces ...... ity and viral RNA replication.

@en

Hepatitis C virus NS2/3 proces ...... ity and viral RNA replication.

@nl

type

label

Hepatitis C virus NS2/3 proces ...... ity and viral RNA replication.

@ast

Hepatitis C virus NS2/3 proces ...... ity and viral RNA replication.

@en

Hepatitis C virus NS2/3 proces ...... ity and viral RNA replication.

@nl

prefLabel

Hepatitis C virus NS2/3 proces ...... ity and viral RNA replication.

@ast

Hepatitis C virus NS2/3 proces ...... ity and viral RNA replication.

@en

Hepatitis C virus NS2/3 proces ...... ity and viral RNA replication.

@nl

P1433

Q34429108-4FF9F7BC-557A-4DF4-87B9-33EC40D41491

P1476

Q34429108-1593A7FC-8960-49C7-9E4A-36C08D730730

P2093

Q34429108-39EA6D9E-9CFC-4421-B01E-141030CF84FF

Q34429108-6D33EC7A-3680-4DCC-AB6C-35B670F972BF

Q34429108-81457832-089E-44B4-A11E-1FE8C05F4194

Q34429108-8FBEAEC2-7BE6-4591-A9EE-CA9FA45AD2FE

Q34429108-94D08F89-C799-4E76-83E9-47BE7735E28C

Q34429108-976F73B2-45A2-45F5-9197-53800A92856F

P2860

Q34429108-013A73EB-2BA3-4F09-BF6D-8F5A324623D5

Q34429108-022FD4B1-9706-46ED-9EB8-809C10FB8A5B

Q34429108-06E0BB2E-C2F0-4A2D-91E3-A7D1F591E53A

Q34429108-132A596F-74FB-4E9B-BEED-A1096EAF7EF3

Q34429108-19DF75E0-CF90-4C4E-9DD2-6458AA11C51D

Q34429108-2A1A4CED-C5D4-4A1A-AE2E-319383E6E11C

Q34429108-2A5E0F47-058B-4E29-BC52-B2EB5371E3D5

Q34429108-34B132C6-E719-4DB2-B563-B69CA28B706D

Q34429108-3C2785B3-1F38-4427-A1D7-A30258608146

Q34429108-3C355454-39E0-455E-993E-7E07615C51DC

P304

Q34429108-62F2E19A-A262-49B2-BD7D-3F4AB76C2BC8

P31

Q34429108-719AA92D-8AAE-4A04-8A72-4AB64EE9D5BE

P356

Q34429108-F1F8E71F-0629-4E80-8C52-699D0FD1DBCA

P407

Q34429108-ED10D1A1-5CFB-43B4-BC69-752C2EC8058E

P433

Q34429108-5E5F134B-0144-4E7B-BB3E-6B0303283D6B

P478

Q34429108-AA79F98D-E662-4856-A813-597B564C4B7A

P50

Q34429108-15753E6A-2830-49F0-A50A-9DA3E286F908

Q34429108-2F289D61-6CC9-4488-A79B-2A030901F2B6

P577

Q34429108-551E4796-CA3F-48BE-91C8-CB1B2C0337C1

P698

Q34429108-1311613D-8B01-48CD-AC51-8C7845FF6178

P356

P1433

Journal of Biological Chemistry

P1476

Hepatitis C virus NS2/3 proces ...... ity and viral RNA replication.

@en

P2093

Arnim Pause

http://www.w3.org/2001/XMLSchema#string

Isabelle Gamache

http://www.w3.org/2001/XMLSchema#string

Karen Meerovitch

http://www.w3.org/2001/XMLSchema#string

Robin Green

http://www.w3.org/2001/XMLSchema#string

Sarah Welbourn

http://www.w3.org/2001/XMLSchema#string

Serge Dandache

http://www.w3.org/2001/XMLSchema#string

P2860

The hepatitis C virus NS2 protein is an inhibitor of CIDE-B-induced apoptosis

Interaction with a ubiquitin-like protein enhances the ubiquitination and degradation of hepatitis C virus RNA-dependent RNA polymerase

Inhibition of RIG-I-dependent signaling to the interferon pathway during hepatitis C virus expression and restoration of signaling by IKKepsilon.

Hepatitis C virus-encoded enzymatic activities and conserved RNA elements in the 3' nontranslated region are essential for virus replication in vivo

Subcellular localization, stability, and trans-cleavage competence of the hepatitis C virus NS3-NS4A complex expressed in tetracycline-regulated cell lines.

Mutations in Hepatitis C Virus RNAs Conferring Cell Culture Adaptation

Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations.

Characterization of the hepatitis C virus NS2/3 processing reaction by using a purified precursor protein

Sequences in the 5' nontranslated region of hepatitis C virus required for RNA replication.

The hepatitis C viral NS3 protein is a processive DNA helicase with cofactor enhanced RNA unwinding.

P304

29604-29611

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M505019200

http://www.w3.org/2001/XMLSchema#string

P407

P433

33

http://www.w3.org/2001/XMLSchema#string

P478

280

http://www.w3.org/2001/XMLSchema#string

P50

Ralf Bartenschlager

P577

2005-06-24T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

15980068

http://www.w3.org/2001/XMLSchema#string