Maternal age effect and severe germ-line bottleneck in the inheritance of human mitochondrial DNA. - sprookjes - yvandenbroek - TriplyDB

Maternal age effect and severe germ-line bottleneck in the inheritance of human mitochondrial DNA.

Maternal age effect and severe germ-line bottleneck in the inheritance of human mitochondrial DNA.

http://www.wikidata.org/entity/Q34442103

about

CRISPR/Cas9 and mitochondrial gene replacement therapy: promising techniques and ethical considerations Mitochondrial DNA heteroplasmy in the emerging field of massively parallel sequencing Genetic Evidence for Elevated Pathogenicity of Mitochondrial DNA Heteroplasmy in Autism Spectrum Disorder Maternal ancestry and population history from whole mitochondrial genomes Segregation of Naturally Occurring Mitochondrial DNA Variants in a Mini-Pig Model Accurate typing of short tandem repeats from genome-wide sequencing data and its applications.Streamlined analysis of duplex sequencing data with Du Novo.Spontaneous Mutation Rate in the Smallest Photosynthetic Eukaryotes Mito-nuclear co-evolution: the positive and negative sides of functional ancient mutations Mitochondrial DNA sequence variation is largely conserved at birth with rare de novo mutations in neonates.Assessing Mitochondrial DNA Variation and Copy Number in Lymphocytes of ~2,000 Sardinians Using Tailored Sequencing Analysis Tools Oocyte mitochondrial function and reproduction.Jupyter and Galaxy: Easing entry barriers into complex data analyses for biomedical researchers.Mitochondrial DNA sequence characteristics modulate the size of the genetic bottleneck Transmission of human mtDNA heteroplasmy in the Genome of the Netherlands families: support for a variable-size bottleneck.Selective removal of deletion-bearing mitochondrial DNA in heteroplasmic Drosophila.Inherited mitochondrial genomic instability and chemical exposures.Ovarian ageing: the role of mitochondria in oocytes and follicles.Genetic Counselling for Maternally Inherited Mitochondrial Disorders.Spinocerebellar ataxia type 3/Machado-Joseph disease: segregation patterns and factors influencing instability of expanded CAG transmissions.Accurate quantitation of circulating cell-free mitochondrial DNA in plasma by droplet digital PCR.The molecular characterization of porcine egg precursor cells.Reproductive aging is associated with changes in oocyte mitochondrial dynamics, function, and mtDNA quantity.The First Mitochondrial Genomics and Evolution SMBE-Satellite Meeting: A New Scientific Symbiosis.Sources, mechanisms, and consequences of chemical-induced mitochondrial toxicity.Parental influence on human germline de novo mutations in 1,548 trios from Iceland.Mitochondrial Mutation Rate, Spectrum and Heteroplasmy in Caenorhabditis elegans Spontaneous Mutation Accumulation Lines of Differing Population Size.Deep sequencing shows that oocytes are not prone to accumulate mtDNA heteroplasmic mutations during ovarian ageing.Replication Errors Made During Oogenesis Lead to Detectable De Novo mtDNA Mutations in Zebrafish Oocytes with a Low mtDNA Copy Number.A Population Phylogenetic View of Mitochondrial Heteroplasmy.Deep-Coverage MPS Analysis of Heteroplasmic Variants within the mtGenome Allows for Frequent Differentiation of Maternal Relatives.Accurate and comprehensive analysis of single nucleotide variants and large deletions of the human mitochondrial genome in DNA and single cells.MPS analysis of the mtDNA hypervariable regions on the MiSeq with improved enrichment.Genetic Diversity on the Sex Chromosomes.Influence of Maternal Aging on Mitochondrial Heterogeneity, Inheritance, and Function in Oocytes and Preimplantation Embryos.Large-scale genetic analysis reveals mammalian mtDNA heteroplasmy dynamics and variance increase through lifetimes and generations.Biological compatibility between two temperate lineages of brown dog ticks, Rhipicephalus sanguineus (sensu lato).Random Mutagenesis, Clonal Events, and Embryonic or Somatic Origin Determine the mtDNA Variant Type and Load in Human Pluripotent Stem Cells Population level mitogenomics of long-lived bats reveals dynamic heteroplasmy and challenges the Free Radical Theory of Ageing

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Maternal age effect and severe germ-line bottleneck in the inheritance of human mitochondrial DNA.

http://www.wikidata.org/entity/Q34442103

description

2014 nî lūn-bûn

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2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2014 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年學術文章

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Maternal age effect and severe ...... ce of human mitochondrial DNA.

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Maternal age effect and severe ...... ce of human mitochondrial DNA.

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Maternal age effect and severe ...... ce of human mitochondrial DNA.

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Maternal age effect and severe ...... ce of human mitochondrial DNA.

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Maternal age effect and severe ...... ce of human mitochondrial DNA.

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Maternal age effect and severe ...... ce of human mitochondrial DNA.

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Maternal age effect and severe ...... ce of human mitochondrial DNA.

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Maternal age effect and severe ...... ce of human mitochondrial DNA.

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Maternal age effect and severe ...... ce of human mitochondrial DNA.

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PNAS.1409328111

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Proceedings of the National Academy of Sciences of the United States of America

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Maternal age effect and severe ...... ce of human mitochondrial DNA.

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Boris Rebolledo-Jaramillo

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Francesca Chiaromonte

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Jennifer A McElhoe

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Kateryna D Makova

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Marcia Shu-Wei Su

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Mitchell M Holland

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Nicholas Stoler

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The pedigree rate of sequence divergence in the human mitochondrial genome: there is a difference between phylogenetic and pedigree rates

The mutation rate in the human mtDNA control region

Evolution of the mutation rate

Rate of de novo mutations and the importance of father's age to disease risk

Oxidative stress is not a major contributor to somatic mitochondrial DNA mutations

High-throughput droplet digital PCR system for absolute quantitation of DNA copy number

Mutation and evolutionary rates in adélie penguins from the antarctic

Heteroplasmy for the 1555A>G mutation in the mitochondrial 12S rRNA gene in six Spanish families with non-syndromic hearing loss.

The effect of strand bias in Illumina short-read sequencing data

Direct estimation of the mitochondrial DNA mutation rate in Drosophila melanogaster

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10.1073/PNAS.1409328111

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43

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111

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Anton Nekrutenko

Francesca Chiaromonte

Thorfinn Korneliussen

Daniel Blankenberg

Benjamin Dickins

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2014-10-13T00:00:00Z

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267749297

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25313049

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mitochondrial DNA

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4217420

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