Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice. - sprookjes - yvandenbroek - TriplyDB

Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice.

Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice.

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Strategies for Human Tumor Virus Discoveries: From Microscopic Observation to Digital Transcriptome Subtraction In Vitro and In Vivo Models for the Study of Human Polyomavirus Infection The role of Merkel cell polyomavirus and other human polyomaviruses in emerging hallmarks of cancer Large T and small T antigens of Merkel cell polyomavirus.CDK1 substitutes for mTOR kinase to activate mitotic cap-dependent protein translation Restricted protein phosphatase 2A targeting by Merkel cell polyomavirus small T antigen.Ectopic Atoh1 expression drives Merkel cell production in embryonic, postnatal and adult mouse epidermis Human BK Polyomavirus-The Potential for Head and Neck Malignancy and Disease Merkel Cell Polyomavirus Small T Antigen Induces Cancer and Embryonic Merkel Cell Proliferation in a Transgenic Mouse Model The Oncogenic Small Tumor Antigen of Merkel Cell Polyomavirus Is an Iron-Sulfur Cluster Protein That Enhances Viral DNA Replication Next generation sequencing of Cytokeratin 20-negative Merkel cell carcinoma reveals ultraviolet-signature mutations and recurrent TP53 and RB1 inactivation Secretomic analysis of extracellular vesicles originating from Polyomavirus-negative and Polyomavirus-positive merkel cell carcinoma cell lines.Rationale for immune-based therapies in Merkel polyomavirus-positive and -negative Merkel cell carcinomas.Merkel cell polyomavirus infection and Merkel cell carcinoma.How does the Merkel polyomavirus lead to a lethal cancer? Many answers, many questions, and a new mouse model.RB1 is the crucial target of the Merkel cell polyomavirus Large T antigen in Merkel cell carcinoma cells.Merkel cell polyomavirus and Merkel cell carcinoma.Merkel cell polyomavirus small T antigen induces genome instability by E3 ubiquitin ligase targeting.Merkel Cell Polyomavirus Small T Antigen Initiates Merkel Cell Carcinoma-like Tumor Development in Mice.Protein-mediated viral latency is a novel mechanism for Merkel cell polyomavirus persistence.Spontaneous lung metastasis formation of human Merkel cell carcinoma cell lines transplanted into scid mice.Low viral load of Merkel cell polyomavirus in Iranian patients with head and neck squamous cell carcinoma: is it clinically important?Stathmin drives virus-induced metastasis.Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis.Human Polyomaviruses: The Battle of Large and Small Tumor Antigens.Merkel cell carcinoma in the age of immunotherapy: Facts and hopes.Are there multiple cells of origin of Merkel cell carcinoma?Epidemiology, biology and therapy of Merkel cell carcinoma: conclusions from the EU project IMMOMEC.Biology and evolution of poorly differentiated neuroendocrine tumors.[Merkel cell carcinoma: cutaneous manifestation of a highly malignant pre-/pro-B cell neoplasia? : Novel concept about the cellular origin of Merkel cell carcinoma].

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P2860

Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice.

http://www.wikidata.org/entity/Q34443490

description

2014 nî lūn-bûn

@nan

2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年學術文章

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name

Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice.

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Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice.

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Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice.

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type

label

Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice.

@ast

Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice.

@en

Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice.

@nl

prefLabel

Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice.

@ast

Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice.

@en

Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice.

@nl

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Journal of Investigative Dermatology

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Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice

@en

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Alexandre N Ermilov

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Andrzej A Dlugosz

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Christopher K Bichakjian

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Dawn M Wilbert

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Doris Mangelberger

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Jack W Weick

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Michael J Imperiale

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Monique E Verhaegen

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Timothy M Johnson

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Tracy D Vozheiko

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P2860

p63 Expression in Merkel Cell Carcinoma Predicts Poorer Survival yet May Have Limited Clinical Utility

Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties

Human Merkel cell polyomavirus small T antigen is an oncoprotein targeting the 4E-BP1 translation regulator

T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus

Mammalian Merkel cells are descended from the epidermal lineage

Epidermal progenitors give rise to Merkel cells during embryonic development and adult homeostasis

Merkel cells are essential for light-touch responses.

Clonal integration of a polyomavirus in human Merkel cell carcinoma

Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase

The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling

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1415-1424

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10.1038/JID.2014.446

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135

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Thomas L Saunders

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2014-10-14T00:00:00Z

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