The cytoplasmic peptide:N-glycanase (Ngly1)-basic science encounters a human genetic disorder.
about
Endo-β-N-acetylglucosaminidase forms N-GlcNAc protein aggregates during ER-associated degradation in Ngly1-defective cellsThe cytoplasmic peptide:N-glycanase (NGLY1) - Structure, expression and cellular functionsLethality of mice bearing a knockout of the Ngly1-gene is partially rescued by the additional deletion of the Engase gene.Novel small molecule binders of human N-glycanase 1, a key player in the endoplasmic reticulum associated degradation pathway.Generation and degradation of free asparagine-linked glycans.Non-lysosomal Degradation of Singly Phosphorylated Oligosaccharides Initiated by the Action of a Cytosolic Endo-β-N-acetylglucosaminidaseProspective phenotyping of NGLY1-CDDG, the first congenital disorder of deglycosylation.Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity.Mitochondrial function requires NGLY1.Occurrence of free sialyl oligosaccharides related to N-glycans (sialyl free N-glycans) in animal sera.Transcriptome and functional analysis in a Drosophila model of NGLY1 deficiency provides insight into therapeutic approaches.Defects in the Neuroendocrine Axis Contribute to Global Development Delay in a Drosophila Model of NGLY1 Deficiency.
P2860
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P2860
The cytoplasmic peptide:N-glycanase (Ngly1)-basic science encounters a human genetic disorder.
description
2014 nî lūn-bûn
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2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
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2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
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name
The cytoplasmic peptide:N-glyc ...... ters a human genetic disorder.
@ast
The cytoplasmic peptide:N-glyc ...... ters a human genetic disorder.
@en
The cytoplasmic peptide:N-glycanase
@nl
type
label
The cytoplasmic peptide:N-glyc ...... ters a human genetic disorder.
@ast
The cytoplasmic peptide:N-glyc ...... ters a human genetic disorder.
@en
The cytoplasmic peptide:N-glycanase
@nl
prefLabel
The cytoplasmic peptide:N-glyc ...... ters a human genetic disorder.
@ast
The cytoplasmic peptide:N-glyc ...... ters a human genetic disorder.
@en
The cytoplasmic peptide:N-glycanase
@nl
P2860
P356
P1476
The cytoplasmic peptide:N-glyc ...... ters a human genetic disorder.
@en
P2093
Tadashi Suzuki
P2860
P356
10.1093/JB/MVU068
P50
P577
2014-11-13T00:00:00Z