Heparan sulfate regulates VEGF165- and VEGF121-mediated vascular hyperpermeability. - sprookjes - yvandenbroek - TriplyDB

Heparan sulfate regulates VEGF165- and VEGF121-mediated vascular hyperpermeability.

Heparan sulfate regulates VEGF165- and VEGF121-mediated vascular hyperpermeability.

http://www.wikidata.org/entity/Q34452740

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Endorepellin, the angiostatic module of perlecan, interacts with both the α2β1 integrin and vascular endothelial growth factor receptor 2 (VEGFR2): a dual receptor antagonism Hallmarks of glycosylation in cancer Pathophysiology of heparan sulphate: many diseases, few drugs Regulatory role of glycans in the control of hypoxia-driven angiogenesis and sensitivity to anti-angiogenic treatment Extracellular regulation of VEGF: isoforms, proteolysis, and vascular patterning.Stable RAGE-Heparan Sulfate Complexes Are Essential for Signal Transduction Blood vessels as targets in tumor therapy Fell-Muir Lecture: Heparan sulphate and the art of cell regulation: a polymer chain conducts the protein orchestra.Endothelial and leukocyte heparan sulfates regulate the development of allergen-induced airway remodeling in a mouse model VEGF-A isoforms differentially regulate ATF-2-dependent VCAM-1 gene expression and endothelial-leukocyte interactions.CD47 signaling regulates the immunosuppressive activity of VEGF in T cells.Heparan sulfate proteoglycans.Integrin-dependent and -independent functions of astrocytic fibronectin in retinal angiogenesis.Diversity of heparan sulfate and HSV entry: basic understanding and treatment strategies.Heparan sulfate sulfatase SULF2 regulates PDGFRα signaling and growth in human and mouse malignant glioma Synergistic Binding of Vascular Endothelial Growth Factor-A and Its Receptors to Heparin Selectively Modulates Complex Affinity.Heparan sulfate is essential for high mobility group protein 1 (HMGB1) signaling by the receptor for advanced glycation end products (RAGE).Novel Interaction Mechanism of a Domain Antibody-based Inhibitor of Human Vascular Endothelial Growth Factor with Greater Potency than Ranibizumab and Bevacizumab and Improved Capacity over Aflibercept.CD47 signaling pathways controlling cellular differentiation and responses to stress.Growth factor restriction impedes progression of wound healing following cataract surgery: identification of VEGF as a putative therapeutic target.Functional Importance of a Proteoglycan Coreceptor in Pathologic Lymphangiogenesis Heparan sulfates mediate the interaction between platelet endothelial cell adhesion molecule-1 (PECAM-1) and the Gαq/11 subunits of heterotrimeric G proteins.Neuropilin signalling in angiogenesis.Heparan sulfate in angiogenesis: a target for therapy.Glycosaminoglycan and DNA Binding Induced Intra- and Intermolecular Exciton Coupling of the bis-4-Aminoquinoline Surfen.Heparin/Heparan sulfate proteoglycans glycomic interactome in angiogenesis: biological implications and therapeutical use.Quantitative phosphoproteomics analysis reveals broad regulatory role of heparan sulfate on endothelial signaling.Targeting heparin and heparan sulfate protein interactions.Novel Heparin Receptor Transmembrane Protein 184a Regulates Angiogenesis in the Adult Zebrafish Caudal Fin.VEGF-A isoforms program differential VEGFR2 signal transduction, trafficking and proteolysis.The Role of the Endothelium in HPS Pathogenesis and Potential Therapeutic Approaches.MicroRNA-24 suppression of N-deacetylase/N-sulfotransferase-1 (NDST1) reduces endothelial cell responsiveness to vascular endothelial growth factor A (VEGFA).Small Molecule Antagonist of Cell Surface Glycosaminoglycans Restricts Mouse Embryonic Stem Cells in a Pluripotent State.More than a biomarker: the systemic consequences of heparan sulfate fragments released during endothelial surface layer degradation (2017 Grover Conference Series).Surfen, a proteoglycan binding agent, reduces inflammation but inhibits remyelination in murine models of Multiple Sclerosis.VEGF-A121a binding to Neuropilins - A concept revisited.Endomucin inhibits VEGF-induced endothelial cell migration, growth, and morphogenesis by modulating VEGFR2 signaling.The interaction of heparan sulfate proteoglycans with endothelial transglutaminase-2 limits VEGF165-induced angiogenesis.Molecular Pharmacology of VEGF-A Isoforms: Binding and Signalling at VEGFR2.

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Heparan sulfate regulates VEGF165- and VEGF121-mediated vascular hyperpermeability.

http://www.wikidata.org/entity/Q34452740

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

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name

Heparan sulfate regulates VEGF165- and VEGF121-mediated vascular hyperpermeability.

@ast

Heparan sulfate regulates VEGF165- and VEGF121-mediated vascular hyperpermeability.

@en

Heparan sulfate regulates VEGF165- and VEGF121-mediated vascular hyperpermeability.

@nl

type

label

Heparan sulfate regulates VEGF165- and VEGF121-mediated vascular hyperpermeability.

@ast

Heparan sulfate regulates VEGF165- and VEGF121-mediated vascular hyperpermeability.

@en

Heparan sulfate regulates VEGF165- and VEGF121-mediated vascular hyperpermeability.

@nl

prefLabel

Heparan sulfate regulates VEGF165- and VEGF121-mediated vascular hyperpermeability.

@ast

Heparan sulfate regulates VEGF165- and VEGF121-mediated vascular hyperpermeability.

@en

Heparan sulfate regulates VEGF165- and VEGF121-mediated vascular hyperpermeability.

@nl

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JBC.M110.177006

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Journal of Biological Chemistry

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Heparan sulfate regulates VEGF165- and VEGF121-mediated vascular hyperpermeability

@en

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Jeffrey D Esko

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Mark M Fuster

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Roger Lawrence

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P2860

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization

Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin

Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor

Structural basis for ligand and heparin binding to neuropilin B domains

Glypican-1 is a VEGF165 binding proteoglycan that acts as an extracellular chaperone for VEGF165

The splice variants of vascular endothelial growth factor (VEGF) and their receptors

Neuropilin-1 binds vascular endothelial growth factor 165, placenta growth factor-2, and heparin via its b1b2 domain

Vascular endothelial growth factor receptor-2: structure, function, intracellular signalling and therapeutic inhibition

Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188

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