Activation of NFAT signaling in podocytes causes glomerulosclerosis. - sprookjes - yvandenbroek - TriplyDB

Activation of NFAT signaling in podocytes causes glomerulosclerosis.

Activation of NFAT signaling in podocytes causes glomerulosclerosis.

http://www.wikidata.org/entity/Q34455455

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Podocytes Cell biology and pathology of podocytes Calcium regulates podocyte actin dynamics.Transient receptor potential channels as therapeutic targets Calcium/NFAT signalling promotes early nephrogenesis NFAT2 inhibitor ameliorates diabetic nephropathy and podocyte injury in db/db mice Transient receptor potential (TRP) channels: a clinical perspective The calcineurin-NFAT pathway allows for urokinase receptor-mediated beta3 integrin signaling to cause podocyte injury.Non-immunologic actions of calcineurin inhibitors in proteinuric kidney diseases.Glomerular proteinuria: a complex interplay between unique players.Calcineurin (CN) activation promotes apoptosis of glomerular podocytes both in vitro and in vivo Angiotensin II contributes to podocyte injury by increasing TRPC6 expression via an NFAT-mediated positive feedback signaling pathway.Podocyte biology for the bedside Gq signaling causes glomerular injury by activating TRPC6.Insulin increases surface expression of TRPC6 channels in podocytes: role of NADPH oxidases and reactive oxygen species.Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction.Transcriptional dysregulation in the ureteric bud causes multicystic dysplastic kidney by branching morphogenesis defect.miR-135 family members mediate podocyte injury through the activation of Wnt/β-catenin signaling.MiR-30a Inhibits the Epithelial--Mesenchymal Transition of Podocytes through Downregulation of NFATc3 MicroRNA-30 family members regulate calcium/calcineurin signaling in podocytes Sustained activation of N-methyl-D-aspartate receptors in podoctyes leads to oxidative stress, mobilization of transient receptor potential canonical 6 channels, nuclear factor of activated T cells activation, and apoptotic cell death.Twenty years after ACEIs and ARBs: emerging treatment strategies for diabetic nephropathy.Unsupervised labeling of glomerular boundaries using Gabor filters and statistical testing in renal histology.Dentin phosphophoryn activates Smad protein signaling through Ca2+-calmodulin-dependent protein kinase II in undifferentiated mesenchymal cells Role of calcineurin (CN) in kidney glomerular podocyte: CN inhibitor ameliorated proteinuria by inhibiting the redistribution of CN at the slit diaphragm.Gain-of-function mutations in transient receptor potential C6 (TRPC6) activate extracellular signal-regulated kinases 1/2 (ERK1/2)Calcium-permeable ion channels in the kidney.TRPC6 channel activation promotes neonatal glomerular mesangial cell apoptosis via calcineurin/NFAT and FasL/Fas signaling pathways.Calmodulin-dependent protein kinase II/cAMP response element-binding protein/Wnt/β-catenin signaling cascade regulates angiotensin II-induced podocyte injury and albuminuria.The podocyte as a direct target for treatment of glomerular disease?Activation of NFAT signaling establishes a tumorigenic microenvironment through cell autonomous and non-cell autonomous mechanisms.Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury.Calcineurin inhibitors cyclosporin A and tacrolimus protect against podocyte injury induced by puromycin aminonucleoside in rodent models Calcineurin regulation of cytoskeleton organization: a new paradigm to analyse the effects of calcineurin inhibitors on the kidney.Balancing calcium signals through TRPC5 and TRPC6 in podocytes.NFAT gene family in inflammation and cancer.Signal transduction in podocytes--spotlight on receptor tyrosine kinases.How many Achilles' heels does a podocyte have? An update on podocyte biology.Primary focal segmental glomerulosclerosis: miRNAs and targeted therapies.Pleiotropic signaling evoked by tumor necrosis factor in podocytes.

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P2860

Activation of NFAT signaling in podocytes causes glomerulosclerosis.

http://www.wikidata.org/entity/Q34455455

description

2010 nî lūn-bûn

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2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հուլիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Activation of NFAT signaling in podocytes causes glomerulosclerosis.

@ast

Activation of NFAT signaling in podocytes causes glomerulosclerosis.

@en

Activation of NFAT signaling in podocytes causes glomerulosclerosis.

@nl

type

label

Activation of NFAT signaling in podocytes causes glomerulosclerosis.

@ast

Activation of NFAT signaling in podocytes causes glomerulosclerosis.

@en

Activation of NFAT signaling in podocytes causes glomerulosclerosis.

@nl

prefLabel

Activation of NFAT signaling in podocytes causes glomerulosclerosis.

@ast

Activation of NFAT signaling in podocytes causes glomerulosclerosis.

@en

Activation of NFAT signaling in podocytes causes glomerulosclerosis.

@nl

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Journal of the American Society of Nephrology

P1476

Activation of NFAT signaling in podocytes causes glomerulosclerosis.

@en

P2093

Daniel R Martin

http://www.w3.org/2001/XMLSchema#string

Feng Chen

http://www.w3.org/2001/XMLSchema#string

George Jarad

http://www.w3.org/2001/XMLSchema#string

Helen Liapis

http://www.w3.org/2001/XMLSchema#string

Jeanette Cunningham

http://www.w3.org/2001/XMLSchema#string

Jeffrey H Miner

http://www.w3.org/2001/XMLSchema#string

Minggui Pan

http://www.w3.org/2001/XMLSchema#string

Piyush Tripathi

http://www.w3.org/2001/XMLSchema#string

Yinqiu Wang

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P2860

TRPC6 in glomerular health and disease: what we know and what we believe

Conditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline induction.

Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature

NFAT signaling: choreographing the social lives of cells

Proteinuria precedes podocyte abnormalities inLamb2-/- mice, implicating the glomerular basement membrane as an albumin barrier

TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function

Integrative genomics identifies DSCR1 (RCAN1) as a novel NFAT-dependent mediator of phenotypic modulation in vascular smooth muscle cells.

Calcineurin is required in urinary tract mesenchyme for the development of the pyeloureteral peristaltic machinery.

Cyclosporin in idiopathic glomerular disease associated with the nephrotic syndrome : workshop recommendations.

The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A.

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1657-1666

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10.1681/ASN.2009121253

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10

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21

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2010-07-22T00:00:00Z

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20651158

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3013542

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