In vivo disruption of TGF-beta signaling by Smad7 leads to premalignant ductal lesions in the pancreas
about
Transforming growth factor β signaling overcomes dasatinib resistance in lung cancerInactivation of TIF1gamma cooperates with Kras to induce cystic tumors of the pancreas.Targeting the transforming growth factor-beta signaling pathway in human cancer.In vivo disruption of TGF-beta signaling by Smad7 in airway epithelium alleviates allergic asthma but aggravates lung carcinogenesis in mouse.Cancer associated fibroblasts in cancer pathogenesisCancer models, genomic instability and somatic cellular Darwinian evolutionTrigenic neural crest-restricted Smad7 over-expression results in congenital craniofacial and cardiovascular defects.Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression.Bone morphogenetic protein 3 controls insulin gene expression and is down-regulated in INS-1 cells inducibly expressing a hepatocyte nuclear factor 1A-maturity-onset diabetes of the young mutation.Unraveling the biological functions of Smad7 with mouse models.Histological complexities of pancreatic lesions from transgenic mouse models are consistent with biological and morphological heterogeneity of human pancreatic cancer.Targeting Stat3 and Smad7 to restore TGF-β cytostatic regulation of tumor cells in vitro and in vivoChallenges and advances in mouse modeling for human pancreatic tumorigenesis and metastasisM2 macrophages promote beta-cell proliferation by up-regulation of SMAD7.Smad7: not only a regulator, but also a cross-talk mediator of TGF-β signalling.Role of Smad7 in inflammatory bowel diseases.The dual role of Smad7 in the control of cancer growth and metastasis.SPSB1, a Novel Negative Regulator of the Transforming Growth Factor-β Signaling Pathway Targeting the Type II Receptor.Berbamine enhances the antineoplastic activity of gemcitabine in pancreatic cancer cells by activating transforming growth factor-β/Smad signaling.Regulation of TGF-β Family Signaling by Inhibitory Smads.Disseminated tumour cells in bone marrow in experimental colon cancer: metastatic or resident?Inactivation of TGFβ receptor II signalling in pancreatic epithelial cells promotes acinar cell proliferation, acinar-to-ductal metaplasia and fibrosis during pancreatitis.Translational advances and novel therapies for pancreatic ductal adenocarcinoma: hope or hype?Deregulation of Negative Controls on TGF-β1 Signaling in Tumor Progression.
P2860
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P2860
In vivo disruption of TGF-beta signaling by Smad7 leads to premalignant ductal lesions in the pancreas
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
In vivo disruption of TGF-beta ...... ductal lesions in the pancreas
@ast
In vivo disruption of TGF-beta ...... ductal lesions in the pancreas
@en
In vivo disruption of TGF-beta ...... ductal lesions in the pancreas
@nl
type
label
In vivo disruption of TGF-beta ...... ductal lesions in the pancreas
@ast
In vivo disruption of TGF-beta ...... ductal lesions in the pancreas
@en
In vivo disruption of TGF-beta ...... ductal lesions in the pancreas
@nl
prefLabel
In vivo disruption of TGF-beta ...... ductal lesions in the pancreas
@ast
In vivo disruption of TGF-beta ...... ductal lesions in the pancreas
@en
In vivo disruption of TGF-beta ...... ductal lesions in the pancreas
@nl
P2093
P2860
P356
P1476
In vivo disruption of TGF-beta ...... ductal lesions in the pancreas
@en
P2093
Chenzhong Kuang
Shaobo Zhang
Teresa M Stringfield
Zhenzhen Wang
P2860
P304
P356
10.1073/PNAS.0508977103
P407
P577
2006-01-27T00:00:00Z