CSN6 drives carcinogenesis by positively regulating Myc stability. - sprookjes - yvandenbroek - TriplyDB

CSN6 drives carcinogenesis by positively regulating Myc stability.

CSN6 drives carcinogenesis by positively regulating Myc stability.

http://www.wikidata.org/entity/Q34523341

about

CSNAP Is a Stoichiometric Subunit of the COP9 Signalosome ERK2-Dependent Phosphorylation of CSN6 Is Critical in Colorectal Cancer Development The COP9 signalosome and cullin-RING ligases in the heart Circadian Clock Gene CRY2 Degradation Is Involved in Chemoresistance of Colorectal Cancer.CSN6 deregulation impairs genome integrity in a COP1-dependent pathway The cell cycle regulator 14-3-3σ opposes and reverses cancer metabolic reprogramming Regulating the stability and localization of CDK inhibitor p27(Kip1) via CSN6-COP1 axis.COP1 enhances ubiquitin-mediated degradation of p27Kip1 to promote cancer cell growth.COP9 signalosome subunit 6 (CSN6) regulates E6AP/UBE3A in cervical cancer.CSN6 positively regulates c-Jun in a MEKK1-dependent manner.Quercetin-induced apoptosis of HT-29 colon cancer cells via inhibition of the Akt-CSN6-Myc signaling axis.Diversity of COP9 signalosome structures and functional consequences.CSN6-COP1 axis in cancer CSN6 controls the proliferation and metastasis of glioblastoma by CHIP-mediated degradation of EGFR.The COP9 signalosome inhibits Cullin-RING E3 ubiquitin ligases independently of its deneddylase activity.COP9 signalosome subunit CSN5, but not CSN6, is upregulated in lung adenocarcinoma and predicts poor prognosis.FBXW7: a critical tumor suppressor of human cancers

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CSN6 drives carcinogenesis by positively regulating Myc stability.

http://www.wikidata.org/entity/Q34523341

description

2014 nî lūn-bûn

@nan

2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2014 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

CSN6 drives carcinogenesis by positively regulating Myc stability.

@ast

CSN6 drives carcinogenesis by positively regulating Myc stability.

@en

CSN6 drives carcinogenesis by positively regulating Myc stability.

@nl

type

label

CSN6 drives carcinogenesis by positively regulating Myc stability.

@ast

CSN6 drives carcinogenesis by positively regulating Myc stability.

@en

CSN6 drives carcinogenesis by positively regulating Myc stability.

@nl

prefLabel

CSN6 drives carcinogenesis by positively regulating Myc stability.

@ast

CSN6 drives carcinogenesis by positively regulating Myc stability.

@en

CSN6 drives carcinogenesis by positively regulating Myc stability.

@nl

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Nature Communications

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CSN6 drives carcinogenesis by positively regulating Myc stability

@en

P2093

Chieh Tseng

http://www.w3.org/2001/XMLSchema#string

Christopher Gully

http://www.w3.org/2001/XMLSchema#string

Chun-Hui Su

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Edward Wang

http://www.w3.org/2001/XMLSchema#string

Giselle Yeung

http://www.w3.org/2001/XMLSchema#string

Guermarie Velazquez-Torres

http://www.w3.org/2001/XMLSchema#string

Hua Wang

http://www.w3.org/2001/XMLSchema#string

Huamin Wang

http://www.w3.org/2001/XMLSchema#string

Hyun Ho Choi

http://www.w3.org/2001/XMLSchema#string

Ji-Hyun Shin

http://www.w3.org/2001/XMLSchema#string

P2860

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

COP9 signalosome subunit 6 stabilizes COP1, which functions as an E3 ubiquitin ligase for 14-3-3σ

The COP9 complex, a novel multisubunit nuclear regulator involved in light control of a plant developmental switch

Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation

Symmetrical modularity of the COP9 signalosome complex suggests its multifunctionality

A novel protein complex involved in signal transduction possessing similarities to 26S proteasome subunits

Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalpha

Isoform- and cell cycle-dependent substrate degradation by the Fbw7 ubiquitin ligase

Crystal structure of the human COP9 signalosome

Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1.

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5384

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10.1038/NCOMMS6384

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5

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Enrique Fuentes-Mattei

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2014-11-14T00:00:00Z

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268280957

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25395170

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4234183

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