RNA structure of trinucleotide repeats associated with human neurological diseases.
about
Muscleblind proteins regulate alternative splicingFacile FMR1 mRNA structure regulation by interruptions in CGG repeatsStructural studies of CNG repeatsMechanisms of RNA-induced toxicity in CAG repeat disordersThermodynamic characterization of tandem mismatches found in naturally occurring RNAAtomic resolution structure of CAG RNA repeats: structural insights and implications for the trinucleotide repeat expansion diseasesCrystal structures of CGG RNA repeats with implications for fragile X-associated tremor ataxia syndromeCrystallographic characterization of CCG repeatsProgress and challenges for chemical probing of RNA structure inside living cellsRNA-mediated pathogenic mechanisms in polyglutamine diseases and amyotrophic lateral sclerosisG-quadruplexes: Emerging roles in neurodegenerative diseases and the non-coding transcriptomeDrosophila as an In Vivo Model for Human Neurodegenerative DiseaseComputational investigation of RNA CUG repeats responsible for myotonic dystrophy 1Mechanistic determinants of MBNL activityControlling the specificity of modularly assembled small molecules for RNA via ligand module spacing: targeting the RNAs that cause myotonic muscular dystrophyThe role of flexibility in the rational design of modularly assembled ligands targeting the RNAs that cause the myotonic dystrophiesMBNL1 binds GC motifs embedded in pyrimidines to regulate alternative splicing.Oligonucleotide-based strategies to combat polyglutamine diseases.Long tract of untranslated CAG repeats is deleterious in transgenic miceDistinctive structural motifs of RNA G-quadruplexes composed of AGG, CGG and UGG trinucleotide repeats.Two high-throughput screening assays for aberrant RNA-protein interactions in myotonic dystrophy type 1.Structural basis of microRNA length variety.The structural basis of myotonic dystrophy from the crystal structure of CUG repeatsA pathogenic mechanism in Huntington's disease involves small CAG-repeated RNAs with neurotoxic activity.RNA-protein interactions in unstable microsatellite diseases.Tandem repeats discovery service (TReaDS) applied to finding novel cis-acting factors in repeat expansion diseases.MBNL proteins and their target RNAs, interaction and splicing regulation.A superfolding Spinach2 reveals the dynamic nature of trinucleotide repeat-containing RNAInitiation of translation of the FMR1 mRNA Occurs predominantly through 5'-end-dependent ribosomal scanningReversal of RNA missplicing and myotonia after muscleblind overexpression in a mouse poly(CUG) model for myotonic dystrophy.Features of modularly assembled compounds that impart bioactivity against an RNA target.A GAG trinucleotide-repeat polymorphism in the gene for glutathione biosynthetic enzyme, GCLC, affects gene expression through translationPerturbation of the Akt/Gsk3-β signalling pathway is common to Drosophila expressing expanded untranslated CAG, CUG and AUUCU repeat RNAs.Selective inhibition of MBNL1-CCUG interaction by small molecules toward potential therapeutic agents for myotonic dystrophy type 2 (DM2)Structures of trinucleotide repeats in human transcripts and their functional implications.Genes and pathways affected by CAG-repeat RNA-based toxicity in DrosophilaTriplet repeat RNA structure and its role as pathogenic agent and therapeutic targetStructural Insights Reveal the Dynamics of the Repeating r(CAG) Transcript Found in Huntington's Disease (HD) and Spinocerebellar Ataxias (SCAs)Repetitive sequences that shape the human transcriptome.RNA Structures as Mediators of Neurological Diseases and as Drug Targets.
P2860
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P2860
RNA structure of trinucleotide repeats associated with human neurological diseases.
description
2003 nî lūn-bûn
@nan
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
RNA structure of trinucleotide repeats associated with human neurological diseases.
@ast
RNA structure of trinucleotide repeats associated with human neurological diseases.
@en
RNA structure of trinucleotide repeats associated with human neurological diseases.
@nl
type
label
RNA structure of trinucleotide repeats associated with human neurological diseases.
@ast
RNA structure of trinucleotide repeats associated with human neurological diseases.
@en
RNA structure of trinucleotide repeats associated with human neurological diseases.
@nl
prefLabel
RNA structure of trinucleotide repeats associated with human neurological diseases.
@ast
RNA structure of trinucleotide repeats associated with human neurological diseases.
@en
RNA structure of trinucleotide repeats associated with human neurological diseases.
@nl
P2093
P2860
P356
P1476
RNA structure of trinucleotide repeats associated with human neurological diseases.
@en
P2093
Jacek Krol
Krzysztof Sobczak
Mateusz de Mezer
P2860
P304
P356
10.1093/NAR/GKG766
P407
P577
2003-10-01T00:00:00Z