Metabolic profiling of alternative NAD biosynthetic routes in mouse tissues - sprookjes - yvandenbroek - TriplyDB

Metabolic profiling of alternative NAD biosynthetic routes in mouse tissues

Metabolic profiling of alternative NAD biosynthetic routes in mouse tissues

http://www.wikidata.org/entity/Q34572320

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New strategies to maximize therapeutic opportunities for NAMPT inhibitors in oncology Role of NAD+ and mitochondrial sirtuins in cardiac and renal diseases Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model.Nicotinamide riboside is uniquely and orally bioavailable in mice and humans.Physiological and pathophysiological roles of NAMPT and NAD metabolism.Design, synthesis, and evaluation of substituted nicotinamide adenine dinucleotide (NAD(+)) synthetase inhibitors as potential antitubercular agents.Pyridine Dinucleotides from Molecules to Man.Exploring NAD+ metabolism in host-pathogen interactions.Biological Activities of the Essential Oil from Erigeron floribundus.Dietary proanthocyanidins boost hepatic NAD(+) metabolism and SIRT1 expression and activity in a dose-dependent manner in healthy rats.Crystal structure of human nicotinic acid phosphoribosyltransferase.Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells.Circadian and Feeding Rhythms Orchestrate the Diurnal Liver Acetylome.Replicatively senescent human fibroblasts reveal a distinct intracellular metabolic profile with alterations in NAD+ and nicotinamide metabolism.Nicotinamide Phosphoribosyltransferase (NAMPT) as a Therapeutic Target in BRAF-Mutated Metastatic Melanoma.Skeletal muscle overexpression of nicotinamide phosphoribosyl transferase in mice coupled with voluntary exercise augments exercise endurance.Cancer cell metabolic plasticity allows resistance to NAMPT inhibition but invariably induces dependence on LDHA.Quantitative Analysis of NAD Synthesis-Breakdown Fluxes.The Emergence of the Nicotinamide Riboside Kinases in the regulation of NAD+ Metabolism.Aged Nicotinamide Riboside Kinase 2 Deficient Mice Present an Altered Response to Endurance Exercise Training

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Metabolic profiling of alternative NAD biosynthetic routes in mouse tissues

http://www.wikidata.org/entity/Q34572320

description

2014 nî lūn-bûn

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2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2014 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Metabolic profiling of alternative NAD biosynthetic routes in mouse tissues

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Metabolic profiling of alternative NAD biosynthetic routes in mouse tissues

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Metabolic profiling of alternative NAD biosynthetic routes in mouse tissues

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type

label

Metabolic profiling of alternative NAD biosynthetic routes in mouse tissues

@ast

Metabolic profiling of alternative NAD biosynthetic routes in mouse tissues

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Metabolic profiling of alternative NAD biosynthetic routes in mouse tissues

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Metabolic profiling of alternative NAD biosynthetic routes in mouse tissues

@ast

Metabolic profiling of alternative NAD biosynthetic routes in mouse tissues

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Metabolic profiling of alternative NAD biosynthetic routes in mouse tissues

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JOURNAL.PONE.0113939

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Metabolic profiling of alternative NAD biosynthetic routes in mouse tissues

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Francesca Mazzola

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Giulio Magni

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Laura Conforti

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Michele Di Stefano

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Nadia Raffaelli

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Silverio Ruggieri

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Valerio Mori

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P2860

Molecular cloning, chromosomal localization, tissue mRNA levels, bacterial expression, and enzymatic properties of human NMN adenylyltransferase

Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms

Characterization of human brain nicotinamide 5'-mononucleotide adenylyltransferase-2 and expression in human pancreas

The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver

NMNAT1 mutations cause Leber congenital amaurosis

The role of mammalian sirtuins in the regulation of metabolism, aging, and longevity

Quinolinic acid, the inescapable neurotoxin

Structural characterization of a human cytosolic NMN/NaMN adenylyltransferase and implication in human NAD biosynthesis

Nicotinamide mononucleotide synthetase is the key enzyme for an alternative route of NAD biosynthesis in Francisella tularensis

A novel deamido-NAD+-binding site revealed by the trapped NAD-adenylate intermediate in the NAD+ synthetase structure

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e113939

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scholarly article

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10.1371/JOURNAL.PONE.0113939

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Giuseppe Orsomando

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2014-11-25T00:00:00Z

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