Failure of postnatal adaptation of the pulmonary circulation after chronic intrauterine pulmonary hypertension in fetal lambs.
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The Robyn Barst Memorial Lecture: Differences between the fetal, newborn, and adult pulmonary circulations: relevance for age-specific therapies (2013 Grover Conference series)Pulmonary hypertension alters soluble guanylate cyclase activity and expression in pulmonary arteries isolated from fetal lambs.Prenatal programming of pulmonary hypertension induced by chronic hypoxia or ductal ligation in sheepNitric oxide alterations following acute ductal constriction in the fetal lamb: a role for superoxideChronic nitric oxide inhibition in utero produces persistent pulmonary hypertension in newborn lambs.Voltage-dependent anion channel-2 interaction with nitric oxide synthase enhances pulmonary artery endothelial cell nitric oxide productionLong-term exposure to high-altitude chronic hypoxia during gestation induces neonatal pulmonary hypertension at sea level.Chronic intrauterine pulmonary hypertension increases main pulmonary artery stiffness and adventitial remodeling in fetal sheep.Transition from placental to air breathing stimulates haem-oxygenase-1 expression without functional consequence for pulmonary vascular adaptation in pigs and mice.Molecular physiopathogenetic mechanisms and development of new potential therapeutic strategies in persistent pulmonary hypertension of the newbornAltered prostanoid metabolism contributes to impaired angiogenesis in persistent pulmonary hypertension in a fetal lamb modelCinaciguat, a soluble guanylate cyclase activator, augments cGMP after oxidative stress and causes pulmonary vasodilation in neonatal pulmonary hypertension.Risk factors for persistent pulmonary hypertension of the newborn.Depolarization-dependent contraction increase after birth and preservation following long-term hypoxia in sheep pulmonary arteriesIntrauterine pulmonary hypertension impairs angiogenesis in vitro: role of vascular endothelial growth factor nitric oxide signalingIntrauterine endotoxin-induced impairs pulmonary vascular function and right ventricular performance in infant rats and improvement with early vitamin D therapyDecreases in manganese superoxide dismutase expression and activity contribute to oxidative stress in persistent pulmonary hypertension of the newborn.Lung eicosanoids in perinatal rats with congenital diaphragmatic herniaAortopulmonary transposition in the fetus: speculation on pathophysiology and therapy.Antenatal BAY 41-2272 reduces pulmonary hypertension in the rabbit model of congenital diaphragmatic hernia.Hydrogen peroxide decreases endothelial nitric oxide synthase promoter activity through the inhibition of AP-1 activity.Serotonin contributes to high pulmonary vascular tone in a sheep model of persistent pulmonary hypertension of the newbornChronic intrauterine pulmonary hypertension increases endothelial cell Rho kinase activity and impairs angiogenesis in vitroAntenatal betamethasone improves postnatal transition in late preterm lambs with persistent pulmonary hypertension of the newborn.Hydrogen peroxide decreases endothelial nitric oxide synthase promoter activity through the inhibition of Sp1 activityEndothelin-1 impairs angiogenesis in vitro through Rho-kinase activation after chronic intrauterine pulmonary hypertension in fetal sheepIncreased superoxide production contributes to the impaired angiogenesis of fetal pulmonary arteries with in utero pulmonary hypertension.Increased hydrogen peroxide downregulates soluble guanylate cyclase in the lungs of lambs with persistent pulmonary hypertension of the newborn.Prolonged endothelin A receptor blockade attenuates chronic pulmonary hypertension in the ovine fetus.Advances in the diagnosis and management of persistent pulmonary hypertension of the newborn.Reactive oxygen species in pulmonary vascular remodeling.Thoracic and abdominal aortas stiffen through unique extracellular matrix changes in intrauterine growth restricted fetal sheep.Peroxisome proliferator activated receptor-γ-Rho-kinase interactions contribute to vascular remodeling after chronic intrauterine pulmonary hypertension.Persistent pulmonary hypertension of non cardiac cause in a neonatal intensive care unit.Role of reactive oxygen species in neonatal pulmonary vascular disease.Cotyledon and binucleate cell nitric oxide synthase expression in an ovine model of fetal growth restriction.Endothelin-1 decreases endothelial PPARγ signaling and impairs angiogenesis after chronic intrauterine pulmonary hypertension.Selective serotonin reuptake inhibitor exposure constricts the mouse ductus arteriosus in utero.Decreased association of HSP90 impairs endothelial nitric oxide synthase in fetal lambs with persistent pulmonary hypertension.Chronic intrauterine pulmonary hypertension compromises fetal pulmonary artery smooth muscle cell O2 sensing.
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P2860
Failure of postnatal adaptation of the pulmonary circulation after chronic intrauterine pulmonary hypertension in fetal lambs.
description
1989 nî lūn-bûn
@nan
1989 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Failure of postnatal adaptatio ...... y hypertension in fetal lambs.
@ast
Failure of postnatal adaptatio ...... y hypertension in fetal lambs.
@en
Failure of postnatal adaptatio ...... y hypertension in fetal lambs.
@nl
type
label
Failure of postnatal adaptatio ...... y hypertension in fetal lambs.
@ast
Failure of postnatal adaptatio ...... y hypertension in fetal lambs.
@en
Failure of postnatal adaptatio ...... y hypertension in fetal lambs.
@nl
prefLabel
Failure of postnatal adaptatio ...... y hypertension in fetal lambs.
@ast
Failure of postnatal adaptatio ...... y hypertension in fetal lambs.
@en
Failure of postnatal adaptatio ...... y hypertension in fetal lambs.
@nl
P2093
P2860
P356
P1476
Failure of postnatal adaptatio ...... y hypertension in fetal lambs.
@en
P2093
F J Accurso
P F Shanley
P2860
P304
P356
10.1172/JCI114091
P407
P577
1989-06-01T00:00:00Z