Cytochrome P450 7A1 cholesterol 7alpha-hydroxylation: individual reaction steps in the catalytic cycle and rate-limiting ferric iron reduction
about
Kinetic deuterium isotope effects in cytochrome P450 oxidation reactionsCytochrome P450 metabolism of the post-lanosterol intermediates explains enigmas of cholesterol synthesis.Human Cytochrome P450 21A2, the Major Steroid 21-Hydroxylase: STRUCTURE OF THE ENZYME·PROGESTERONE SUBSTRATE COMPLEX AND RATE-LIMITING C-H BOND CLEAVAGECyp27c1 Red-Shifts the Spectral Sensitivity of Photoreceptors by Converting Vitamin A1 into A2.Kinetic analysis of lauric acid hydroxylation by human cytochrome P450 4A11Inhibition of human cytochrome P450 3A4 by cholesterolOrphans in the human cytochrome P450 superfamily: approaches to discovering functions and relevance in pharmacology.Structure-Functional Characterization of Cytochrome P450 Sterol 14α-Demethylase (CYP51B) from Aspergillus fumigatus and Molecular Basis for the Development of Antifungal Drugs.Oxidation of 7-dehydrocholesterol and desmosterol by human cytochrome P450 46A1.Minor activities and transition state properties of the human steroid hydroxylases cytochromes P450c17 and P450c21, from reactions observed with deuterium-labeled substrates.Metabolomic analysis and identification of a role for the orphan human cytochrome P450 2W1 in selective oxidation of lysophospholipidsRole of CAR and PXR in xenobiotic sensing and metabolism.Mapping of the Allosteric Site in Cholesterol Hydroxylase CYP46A1 for Efavirenz, a Drug That Stimulates Enzyme ActivityA delicate balance: Iron metabolism and diseases of the brain.Biometals and their therapeutic implications in Alzheimer's disease.Rapid kinetic methods to dissect steroidogenic cytochrome P450 reaction mechanisms.Conversion of 7-dehydrocholesterol to 7-ketocholesterol is catalyzed by human cytochrome P450 7A1 and occurs by direct oxidation without an epoxide intermediate.Mechanism of the P450-Catalyzed Oxidative Cyclization in the Biosynthesis of Griseofulvin.Hypoxic repression of CYP7A1 through a HIF-1α- and SHP-independent mechanism.Identification of the rate-limiting step of the peroxygenase reactions catalyzed by the thermophilic cytochrome P450 from Sulfolobus tokodaii strain 7.Kinetic Deuterium Isotope Effects in Cytochrome P450 Reactions.Effect of iron on cholesterol 7α-hydroxylase expression in alcohol-induced hepatic steatosis in mice.Selected scientific topics of the 11th International Isotope Symposium on the Synthesis and Applications of Isotopes and Isotopically Labeled Compounds.
P2860
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P2860
Cytochrome P450 7A1 cholesterol 7alpha-hydroxylation: individual reaction steps in the catalytic cycle and rate-limiting ferric iron reduction
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2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年學術文章
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name
Cytochrome P450 7A1 cholestero ...... limiting ferric iron reduction
@ast
Cytochrome P450 7A1 cholestero ...... limiting ferric iron reduction
@en
Cytochrome P450 7A1 cholestero ...... limiting ferric iron reduction
@nl
type
label
Cytochrome P450 7A1 cholestero ...... limiting ferric iron reduction
@ast
Cytochrome P450 7A1 cholestero ...... limiting ferric iron reduction
@en
Cytochrome P450 7A1 cholestero ...... limiting ferric iron reduction
@nl
prefLabel
Cytochrome P450 7A1 cholestero ...... limiting ferric iron reduction
@ast
Cytochrome P450 7A1 cholestero ...... limiting ferric iron reduction
@en
Cytochrome P450 7A1 cholestero ...... limiting ferric iron reduction
@nl
P2860
P356
P1476
Cytochrome P450 7A1 cholestero ...... limiting ferric iron reduction
@en
P2093
F Peter Guengerich
Raku Shinkyo
P2860
P304
P356
10.1074/JBC.M110.193409
P407
P577
2010-12-08T00:00:00Z