Interplay between HIV entry and transportin-SR2 dependency - sprookjes - yvandenbroek - TriplyDB

Interplay between HIV entry and transportin-SR2 dependency

Interplay between HIV entry and transportin-SR2 dependency

http://www.wikidata.org/entity/Q34586080

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Interaction of the HIV-1 intasome with transportin 3 protein (TNPO3 or TRN-SR2)HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency Nuclear trafficking of retroviral RNAs and Gag proteins during late steps of replication Differential effects of human immunodeficiency virus type 1 capsid and cellular factors nucleoporin 153 and LEDGF/p75 on the efficiency and specificity of viral DNA integration The HIV-1 integrase mutant R263A/K264A is 2-fold defective for TRN-SR2 binding and viral nuclear import.Antiviral activity of α-helical stapled peptides designed from the HIV-1 capsid dimerization domain A cyclophilin homology domain-independent role for Nup358 in HIV-1 infection.The requirement for nucleoporin NUP153 during human immunodeficiency virus type 1 infection is determined by the viral capsid.Residual HIV-1 DNA Flap-independent nuclear import of cPPT/CTS double mutant viruses does not support spreading infection Host Factors in Retroviral Integration and the Selection of Integration Target Sites.TNPO3 is required for HIV-1 replication after nuclear import but prior to integration and binds the HIV-1 core.The Role of TNPO3 in HIV-1 Replication.Identification of residues in the C-terminal domain of HIV-1 integrase that mediate binding to the transportin-SR2 protein.Single-cell imaging of HIV-1 provirus (SCIP).The ability of TNPO3-depleted cells to inhibit HIV-1 infection requires CPSF6.Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication.Viral and cellular requirements for the nuclear entry of retroviral preintegration nucleoprotein complexes.N-terminal half of transportin SR2 interacts with HIV integrase.Leukotrienes inhibit early stages of HIV-1 infection in monocyte-derived microglia-like cells Knockdown of the host cellular protein transportin 3 attenuates prototype foamy virus infection.Quantitative microscopy of functional HIV post-entry complexes reveals association of replication with the viral capsid The host proteins transportin SR2/TNPO3 and cyclophilin A exert opposing effects on HIV-1 uncoating.Feline immunodeficiency virus Gag is a nuclear shuttling protein.The cargo-binding domain of transportin 3 is required for lentivirus nuclear import.Dynamics and regulation of nuclear import and nuclear movements of HIV-1 complexes.Capsid-CPSF6 Interaction Is Dispensable for HIV-1 Replication in Primary Cells but Is Selected during Virus Passage In Vivo.Mutations affecting interaction of integrase with TNPO3 do not prevent HIV-1 cDNA nuclear import.Cellular cofactors of lentiviral integrase: from target validation to drug discovery.Interaction of transportin-SR2 with Ras-related nuclear protein (Ran) GTPase Identification of low molecular weight nuclear complexes containing integrase during the early stages of HIV-1 infection.Inhibitors of the integrase-transportin-SR2 interaction block HIV nuclear import.Nup153 Unlocks the Nuclear Pore Complex for HIV-1 Nuclear Translocation in Non-dividing Cells Y-box-binding protein 1 supports the early and late steps of HIV replication

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Interplay between HIV entry and transportin-SR2 dependency

http://www.wikidata.org/entity/Q34586080

description

2011 nî lūn-bûn

@nan

2011 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Interplay between HIV entry and transportin-SR2 dependency

@ast

Interplay between HIV entry and transportin-SR2 dependency

@en

Interplay between HIV entry and transportin-SR2 dependency

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type

label

Interplay between HIV entry and transportin-SR2 dependency

@ast

Interplay between HIV entry and transportin-SR2 dependency

@en

Interplay between HIV entry and transportin-SR2 dependency

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prefLabel

Interplay between HIV entry and transportin-SR2 dependency

@ast

Interplay between HIV entry and transportin-SR2 dependency

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Interplay between HIV entry and transportin-SR2 dependency

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Interplay between HIV entry and transportin-SR2 dependency

@en

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Jan De Rijck

http://www.w3.org/2001/XMLSchema#string

Jonas Demeulemeester

http://www.w3.org/2001/XMLSchema#string

Melanie Gérard

http://www.w3.org/2001/XMLSchema#string

Oliver Taltynov

http://www.w3.org/2001/XMLSchema#string

Renée Vancraenenbroeck

http://www.w3.org/2001/XMLSchema#string

Rik Gijsbers

http://www.w3.org/2001/XMLSchema#string

Stéphanie De Houwer

http://www.w3.org/2001/XMLSchema#string

Wannes Thys

http://www.w3.org/2001/XMLSchema#string

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Transportin-SR, a nuclear import receptor for SR proteins

HIV enters cells via endocytosis and dynamin-dependent fusion with endosomes

A novel splicing regulator shares a nuclear import pathway with SR proteins

Ebola virus uses clathrin-mediated endocytosis as an entry pathway.

LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells

Identification of host proteins required for HIV infection through a functional genomic screen

Importin alpha3 interacts with HIV-1 integrase and contributes to HIV-1 nuclear import and replication

Transportin-SR2 mediates nuclear import of phosphorylated SR proteins

Active nuclear import of human immunodeficiency virus type 1 preintegration complexes

HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway

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10.1186/1742-4690-8-7

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8

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2011-01-30T00:00:00Z

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49793635

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1043754509

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21276267

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3041740

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