The hepatitis C virus NS3 protein: a model RNA helicase and potential drug target
about
Molecular targets for flavivirus drug discoverySimultaneously Targeting the NS3 Protease and Helicase Activities for More Effective Hepatitis C Virus TherapyDocking studies of Pakistani HCV NS3 helicase: a possible antiviral drug targetNS3 Peptide, a Novel Potent Hepatitis C Virus NS3 Helicase Inhibitor: Its Mechanism of Action and Antiviral Activity in the Replicon SystemAnalysis of the Evolutionary Forces in an Immunodominant CD8 Epitope in Hepatitis C Virus at a Population LevelEffects of Mutagenic and Chain-Terminating Nucleotide Analogs on Enzymes Isolated from Hepatitis C Virus Strains of Various GenotypesMonitoring helicase activity with molecular beaconsEscape from HLA-B*08-Restricted CD8 T Cells by Hepatitis C Virus Is Associated with Fitness CostsThe NS4A Protein of Hepatitis C Virus Promotes RNA-Coupled ATP Hydrolysis by the NS3 HelicaseFuel Specificity of the Hepatitis C Virus NS3 HelicaseHelicase inhibitors as specifically targeted antiviral therapy for hepatitis CThree conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism.Mechanism and Specificity of a Symmetrical Benzimidazolephenylcarboxamide Helicase InhibitorA Method to Simultaneously Monitor Hepatitis C Virus NS3 Helicase and Protease ActivitiesVisualizing ATP-Dependent RNA Translocation by the NS3 Helicase from HCVDiscovery of an allosteric mechanism for the regulation of HCV NS3 protein functionThe T4 Phage SF1B Helicase Dda Is Structurally Optimized to Perform DNA Strand SeparationInhibition of both protease and helicase activities of hepatitis C virus NS3 by an ethyl acetate extract of marine sponge Amphimedon spNatural HCV variants with increased replicative fitness due to NS3 helicase mutations in the C-terminal helix α18Tracing entire operation cycles of molecular motor hepatitis C virus helicase in structurally resolved dynamical simulations.Structural studies of Helicase NS3 variants from Hepatitis C virus genotype 3 in virological sustained responder and non-responder patients.Induction of cell-mediated immune responses in mice by DNA vaccines that express hepatitis C virus NS3 mutants lacking serine protease and NTPase/RNA helicase activities.Intracytoplasmic stable expression of IgG1 antibody targeting NS3 helicase inhibits replication of highly efficient hepatitis C Virus 2a clone.RNA helicases: emerging roles in viral replication and the host innate response.Visualization and measurement of ATP levels in living cells replicating hepatitis C virus genome RNA.The core protein of classical Swine Fever virus is dispensable for virus propagation in vitroHepatitis C virus network based classification of hepatocellular cirrhosis and carcinomaIdentification and analysis of hepatitis C virus NS3 helicase inhibitors using nucleic acid binding assaysEbselen inhibits hepatitis C virus NS3 helicase binding to nucleic acid and prevents viral replicationSignificance of monoclonal antibodies against the conserved epitopes within non-structural protein 3 helicase of hepatitis C virusSelective inhibition of DNA replicase assembly by a non-natural nucleotide: exploiting the structural diversity of ATP-binding sitesA genetic interaction between the core and NS3 proteins of hepatitis C virus is essential for production of infectious virusDiscovering new medicines targeting helicases: challenges and recent progress.Benzothiazole and Pyrrolone Flavivirus Inhibitors Targeting the Viral Helicase.Human Enterovirus Nonstructural Protein 2CATPase Functions as Both an RNA Helicase and ATP-Independent RNA ChaperoneAnalysis of the Enzymatic Activity of an NS3 Helicase Genotype 3a Variant Sequence Obtained from a Relapse Patient.Inhibition of hepatitis C virus replication and viral helicase by ethyl acetate extract of the marine feather star Alloeocomatella polycladiaSequence diversity of hepatitis C virus: implications for immune control and therapy.HCV Induces Telomerase Reverse Transcriptase, Increases Its Catalytic Activity, and Promotes Caspase Degradation in Infected Human HepatocytesStructure-based simulations of the translocation mechanism of the hepatitis C virus NS3 helicase along single-stranded nucleic acid.
P2860
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P2860
The hepatitis C virus NS3 protein: a model RNA helicase and potential drug target
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
The hepatitis C virus NS3 protein: a model RNA helicase and potential drug target
@ast
The hepatitis C virus NS3 protein: a model RNA helicase and potential drug target
@en
The hepatitis C virus NS3 protein: a model RNA helicase and potential drug target
@nl
type
label
The hepatitis C virus NS3 protein: a model RNA helicase and potential drug target
@ast
The hepatitis C virus NS3 protein: a model RNA helicase and potential drug target
@en
The hepatitis C virus NS3 protein: a model RNA helicase and potential drug target
@nl
prefLabel
The hepatitis C virus NS3 protein: a model RNA helicase and potential drug target
@ast
The hepatitis C virus NS3 protein: a model RNA helicase and potential drug target
@en
The hepatitis C virus NS3 protein: a model RNA helicase and potential drug target
@nl
P2860
P1476
The hepatitis C virus NS3 protein: a model RNA helicase and potential drug target
@en
P2093
David N Frick
P2860
P577
2007-01-01T00:00:00Z