Depletion of topoisomerase IIalpha leads to shortening of the metaphase interkinetochore distance and abnormal persistence of PICH-coated anaphase threads.
about
RECQL5 cooperates with Topoisomerase II alpha in DNA decatenation and cell cycle progressionSister chromatid decatenation: bridging the gaps in our knowledgeDNA topoisomerase II is a determinant of the tensile properties of yeast centromeric chromatin and the tension checkpointTopBP1/Dpb11 binds DNA anaphase bridges to prevent genome instability.Centromere-associated topoisomerase activity in bloodstream form Trypanosoma bruceiThe evolutionary origin of man can be traced in the layers of defunct ancestral alpha satellites flanking the active centromeres of human chromosomesCondensin regulates the stiffness of vertebrate centromeresContrasting roles of condensin I and condensin II in mitotic chromosome formationOn the regulation, function, and localization of the DNA-dependent ATPase PICH.High mitotic activity of Polo-like kinase 1 is required for chromosome segregation and genomic integrity in human epithelial cells.Haspin: a newly discovered regulator of mitotic chromosome behavior.PICH and cotargeted Plk1 coordinately maintain prometaphase chromosome arm architecture.Canonical non-homologous end joining in mitosis induces genome instability and is suppressed by M-phase-specific phosphorylation of XRCC4Clonality characterization of natural epitope-specific antibodies against the tumor-related antigen topoisomerase IIa by peptide chip and proteome analysis: a pilot study with colorectal carcinoma patient samples.PICH and BLM limit histone association with anaphase centromeric DNA threads and promote their resolution.The analysis of mutant alleles of different strength reveals multiple functions of topoisomerase 2 in regulation of Drosophila chromosome structure.Revised genetic requirements for the decatenation G2 checkpoint: the role of ATM.The NuRD nucleosome remodelling complex and NHK-1 kinase are required for chromosome condensation in oocytes.TOPBP1 recruits TOP2A to ultra-fine anaphase bridges to aid in their resolution.RAD54 family translocases counter genotoxic effects of RAD51 in human tumor cells.Chromosome Scaffold is a Double-Stranded Assembly of Scaffold ProteinsPTEN stabilizes TOP2A and regulates the DNA decatenationLinking abnormal mitosis to the acquisition of DNA damageThe BLM dissolvasome in DNA replication and repair.SUMO modification of DNA topoisomerase II: trying to get a CENse of it allHow unfinished business from S-phase affects mitosis and beyondSmc5/6-mediated regulation of replication progression contributes to chromosome assembly during mitosis in human cells.Building mitotic chromosomesThe α isoform of topoisomerase II is required for hypercompaction of mitotic chromosomes in human cells.Mammalian Fbh1 is important to restore normal mitotic progression following decatenation stress.Studying vertebrate topoisomerase 2 function using a conditional knockdown system in DT40 cells.SUMO-interacting motifs (SIMs) in Polo-like kinase 1-interacting checkpoint helicase (PICH) ensure proper chromosome segregation during mitosis.Mitotic chromosomes are compacted laterally by KIF4 and condensin and axially by topoisomerase IIαCondensin II plays an essential role in reversible assembly of mitotic chromosomes in situ.Molecular basis for the DNA damage induction and anticancer activity of asymmetrically substituted anthrapyridazone PDZ-7.Site-Specific Cleavage by Topoisomerase 2: A Mark of the Core Centromere.Imaging of DNA Ultrafine Bridges in Budding Yeast.53BP1 can limit sister-chromatid rupture and rearrangements driven by a distinct ultrafine DNA bridging-breakage process.Cohesin removal precedes topoisomerase IIα-dependent decatenation at centromeres in male mammalian meiosis II.
P2860
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P2860
Depletion of topoisomerase IIalpha leads to shortening of the metaphase interkinetochore distance and abnormal persistence of PICH-coated anaphase threads.
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Depletion of topoisomerase IIa ...... PICH-coated anaphase threads.
@ast
Depletion of topoisomerase IIa ...... PICH-coated anaphase threads.
@en
Depletion of topoisomerase IIa ...... PICH-coated anaphase threads.
@nl
type
label
Depletion of topoisomerase IIa ...... PICH-coated anaphase threads.
@ast
Depletion of topoisomerase IIa ...... PICH-coated anaphase threads.
@en
Depletion of topoisomerase IIa ...... PICH-coated anaphase threads.
@nl
prefLabel
Depletion of topoisomerase IIa ...... PICH-coated anaphase threads.
@ast
Depletion of topoisomerase IIa ...... PICH-coated anaphase threads.
@en
Depletion of topoisomerase IIa ...... PICH-coated anaphase threads.
@nl
P2093
P2860
P356
P1476
Depletion of topoisomerase IIa ...... PICH-coated anaphase threads.
@en
P2093
Adam J Carpenter
Andrew C G Porter
Christine J Farr
Hui Hui Phua
Jennifer M Spence
Walter Mills
P2860
P304
P356
10.1242/JCS.013730
P407
P577
2007-10-23T00:00:00Z