Nef-mediated disruption of HLA-A2 transport to the cell surface in T cells
about
HIV-1 Nef disrupts intracellular trafficking of major histocompatibility complex class I, CD4, CD8, and CD28 by distinct pathways that share common elementsThe hope for an HIV vaccine based on induction of CD8+ T lymphocytes--a reviewStructure, dynamics, and Hck interaction of full-length HIV-1 Nef.Human immunodeficiency virus type 1 Nef associates with lipid rafts to downmodulate cell surface CD4 and class I major histocompatibility complex expression and to increase viral infectivity.Efficient Vpu-Mediated Tetherin Antagonism by an HIV-1 Group O Strain.HIV-1 Nef targets MHC-I and CD4 for degradation via a final common beta-COP-dependent pathway in T cells.The Epstein-Barr virus G-protein-coupled receptor contributes to immune evasion by targeting MHC class I molecules for degradationAssembly and intracellular trafficking of HLA-B*3501 and HLA-B*3503Small molecule inhibition of HIV-1-induced MHC-I down-regulation identifies a temporally regulated switch in Nef actionHuman immunodeficiency virus-1 Nef expression induces intracellular accumulation of multivesicular bodies and major histocompatibility complex class II complexes: potential role of phosphatidylinositol 3-kinaseHIV-1 Nef down-regulates the hemochromatosis protein HFE, manipulating cellular iron homeostasisNef proteins from diverse groups of primate lentiviruses downmodulate CXCR4 to inhibit migration to the chemokine stromal derived factor 1.At the crossroads of homoeostasis and disease: roles of the PACS proteins in membrane traffic and apoptosis.Nef inhibits glucose uptake in adipocytes and contributes to insulin resistance in human immunodeficiency virus type I infection.ADP ribosylation factor 1 activity is required to recruit AP-1 to the major histocompatibility complex class I (MHC-I) cytoplasmic tail and disrupt MHC-I trafficking in HIV-1-infected primary T cells.Novel peptide-based HIV-1 immunotherapy.A Genome-Wide Screen for Machinery Involved in Downregulation of MHC Class I by HIV-1 Nef.HIV-1 Nef-induced down-regulation of MHC class I requires AP-1 and clathrin but not PACS-1 and is impeded by AP-2.HIV-1 Nef disrupts MHC-I trafficking by recruiting AP-1 to the MHC-I cytoplasmic tail.Cooperative binding of the class I major histocompatibility complex cytoplasmic domain and human immunodeficiency virus type 1 Nef to the endosomal AP-1 complex via its mu subunitHuman immunodeficiency virus type 1 Nef: adapting to intracellular trafficking pathways.Down-modulation of mature major histocompatibility complex class II and up-regulation of invariant chain cell surface expression are well-conserved functions of human and simian immunodeficiency virus nef alleles.HIV-1 Nef binds PACS-2 to assemble a multikinase cascade that triggers major histocompatibility complex class I (MHC-I) down-regulation: analysis using short interfering RNA and knock-out mice.Functional characterization of the human immunodeficiency virus type 1 Nef acidic domain.Adaptor protein 1 promotes cross-presentation through the same tyrosine signal in major histocompatibility complex class I as that targeted by HIV-1.Pathogen evasion strategies for the major histocompatibility complex class I assembly pathway.Immune responses to Epstein-Barr virus: molecular interactions in the virus evasion of CD8+ T cell immunityHuman immunodeficiency virus type 1 Nef domains required for disruption of major histocompatibility complex class I trafficking are also necessary for coprecipitation of Nef with HLA-A2.HIV immune evasion disruption of antigen presentation by the HIV Nef protein.The natural killer cell cytotoxic function is modulated by HIV-1 accessory proteins.Enhancing immunogenicity and cross-reactivity of HIV-1 antigens by in vivo targeting to dendritic cells.The hemochromatosis protein HFE 20 years later: An emerging role in antigen presentation and in the immune systemExpression of Nef downregulates CXCR4, the major coreceptor of human immunodeficiency virus, from the surfaces of target cells and thereby enhances resistance to superinfection.A novel trafficking signal within the HLA-C cytoplasmic tail allows regulated expression upon differentiation of macrophages.Transcription of preintegrated HIV-1 cDNA modulates cell surface expression of major histocompatibility complex class I via Nef.HIV-1 Vpu and HIV-2 Env counteract BST-2/tetherin by sequestration in a perinuclear compartmentIsolation of a monoclonal antibody from a phage display library binding the rhesus macaque MHC class I allomorph Mamu-A1*001.E5 protein of human papillomavirus 16 downregulates HLA class I and interacts with the heavy chain via its first hydrophobic domain.The C terminus of the nucleoprotein of influenza A virus delivers antigens transduced by Tat to the trans-golgi network and promotes an efficient presentation through HLA class I.Requirements for cell rounding and surface protein down-regulation by Ebola virus glycoprotein.
P2860
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P2860
Nef-mediated disruption of HLA-A2 transport to the cell surface in T cells
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2003 nî lūn-bûn
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2003 թուականի Մարտին հրատարակուած գիտական յօդուած
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2003 թվականի մարտին հրատարակված գիտական հոդված
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2003年の論文
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2003年論文
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2003年論文
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Nef-mediated disruption of HLA-A2 transport to the cell surface in T cells
@ast
Nef-mediated disruption of HLA-A2 transport to the cell surface in T cells
@en
Nef-mediated disruption of HLA-A2 transport to the cell surface in T cells
@nl
type
label
Nef-mediated disruption of HLA-A2 transport to the cell surface in T cells
@ast
Nef-mediated disruption of HLA-A2 transport to the cell surface in T cells
@en
Nef-mediated disruption of HLA-A2 transport to the cell surface in T cells
@nl
prefLabel
Nef-mediated disruption of HLA-A2 transport to the cell surface in T cells
@ast
Nef-mediated disruption of HLA-A2 transport to the cell surface in T cells
@en
Nef-mediated disruption of HLA-A2 transport to the cell surface in T cells
@nl
P2860
P1433
P1476
Nef-mediated disruption of HLA-A2 transport to the cell surface in T cells
@en
P2093
Kathleen L Collins
Matthew R Kasper
P2860
P304
P356
10.1128/JVI.77.5.3041-3049.2003
P407
P577
2003-03-01T00:00:00Z