Signaling mechanism of poly(ADP-ribose) polymerase-1 (PARP-1) in inflammatory diseases. - sprookjes - yvandenbroek - TriplyDB

Signaling mechanism of poly(ADP-ribose) polymerase-1 (PARP-1) in inflammatory diseases.

Signaling mechanism of poly(ADP-ribose) polymerase-1 (PARP-1) in inflammatory diseases.

http://www.wikidata.org/entity/Q34755657

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Redox regulation of SIRT1 in inflammation and cellular senescence PARP inhibition in leukocytes diminishes inflammation via effects on integrins/cytoskeleton and protects the blood-brain barrier.Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors Immune Cell Regulatory Pathways Unexplored as Host-Directed Therapeutic Targets for Mycobacterium tuberculosis: An Opportunity to Apply Precision Medicine Innovations to Infectious Diseases Chronic PARP-1 inhibition reduces carotid vessel remodeling and oxidative damage of the dorsal hippocampus in spontaneously hypertensive rats.Advanced oxidation protein products induce intestine epithelial cell death through a redox-dependent, c-jun N-terminal kinase and poly (ADP-ribose) polymerase-1-mediated pathway.Increased DNA damage in progression of COPD: a response by poly(ADP-ribose) polymerase-1.Neurological and histological consequences induced by in vivo cerebral oxidative stress: evidence for beneficial effects of SRT1720, a sirtuin 1 activator, and sirtuin 1-mediated neuroprotective effects of poly(ADP-ribose) polymerase inhibition Changes in Proteome Profile of Peripheral Blood Mononuclear Cells in Chronic Chagas Disease Frataxin Deficiency Promotes Excess Microglial DNA Damage and Inflammation that Is Rescued by PJ34 Role of PARP inhibitors in cancer biology and therapy Minocycline blocks asthma-associated inflammation in part by interfering with the T cell receptor-nuclear factor κB-GATA-3-IL-4 axis without a prominent effect on poly(ADP-ribose) polymerase Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice.Developments in the management of Chagas cardiomyopathy.Daidzein suppresses pro-inflammatory chemokine Cxcl2 transcription in TNF-α-stimulated murine lung epithelial cells via depressing PARP-1 activity Mitotic bookmarking: maintaining post-mitotic reprogramming of transcription reactivation Therapeutic applications of PARP inhibitors: anticancer therapy and beyond Effects of poly (ADP-ribosyl) polymerase (PARP) inhibitor on cisplatin resistance & proliferation of the ovarian cancer C13* cells Whole-exome sequencing and imaging genetics identify functional variants for rate of change in hippocampal volume in mild cognitive impairment.MnSODtg mice control myocardial inflammatory and oxidative stress and remodeling responses elicited in chronic Chagas disease.PARP Inhibitors in Reproductive System Cancers: Current Use and Developments.Effects of an Encapsulated Fruit and Vegetable Juice Concentrate on Obesity-Induced Systemic Inflammation: A Randomised Controlled Trial.PARP1 promotes gene expression at the post-transcriptiona level by modulating the RNA-binding protein HuR.Predictive biomarkers for cancer therapy with PARP inhibitors.Redox regulation of inflammation: old elements, a new story.HeLa cell response proteome alterations induced by mammalian reovirus T3D infection.Macrophages Promote Oxidative Metabolism To Drive Nitric Oxide Generation in Response to Trypanosoma cruzi.Opportunities for the repurposing of PARP inhibitors for the therapy of non-oncological diseases.The clinically used poly(ADP-ribose) polymerase (PARP) inhibitor olaparib improves organ function, suppresses inflammatory responses and accelerates wound healing in a murine model of third-degree burn injury.The immune system's role in sepsis progression, resolution, and long-term outcome.Charon Mediates Immune Deficiency-Driven PARP-1-Dependent Immune Responses in Drosophila.Poly(ADP-Ribose)Polymerase-1 in Lung Inflammatory Disorders: A Review.The poly(adenosine diphosphate-ribose) polymerase inhibitor PJ34 reduces pulmonary ischemia-reperfusion injury in rats Critical Role of ADAMTS-4 in the Development of Sporadic Aortic Aneurysm and Dissection in Mice.Olaparib modulates DNA repair efficiency, sensitizes cervical cancer cells to cisplatin and exhibits anti-metastatic property.Copper-induced immunotoxicity involves cell cycle arrest and cell death in the liver.Inherited variation in the PARP1 gene and survival from melanoma Poly(ADP-ribose)polymerases inhibitors prevent early mitochondrial fragmentation and hepatocyte cell death induced by H2O2.Accelerated Regeneration of ATP Level after Irradiation in Human Skin Fibroblasts by Coenzyme Q10.Anti-apoptotic effect of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) polymerase, against multiple organ damage induced by gamma irradiation in rats.

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P2860

Signaling mechanism of poly(ADP-ribose) polymerase-1 (PARP-1) in inflammatory diseases.

http://www.wikidata.org/entity/Q34755657

description

2011 nî lūn-bûn

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2011 թուականի Մարտին հրատարակուած գիտական յօդուած

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2011 թվականի մարտին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Signaling mechanism of poly

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Signaling mechanism of poly(ADP-ribose) polymerase-1 (PARP-1) in inflammatory diseases.

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Signaling mechanism of poly(ADP-ribose) polymerase-1 (PARP-1) in inflammatory diseases.

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type

label

Signaling mechanism of poly

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Signaling mechanism of poly(ADP-ribose) polymerase-1 (PARP-1) in inflammatory diseases.

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Signaling mechanism of poly(ADP-ribose) polymerase-1 (PARP-1) in inflammatory diseases.

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Signaling mechanism of poly

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Signaling mechanism of poly(ADP-ribose) polymerase-1 (PARP-1) in inflammatory diseases.

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Signaling mechanism of poly(ADP-ribose) polymerase-1 (PARP-1) in inflammatory diseases.

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J.AJPATH.2010.12.004

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The American Journal of Pathology

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Signaling mechanism of poly(ADP-ribose) polymerase-1 (PARP-1) in inflammatory diseases.

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Nisha Jain Garg

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Xueqing Ba

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P2860

Txk, a member of the non-receptor tyrosine kinase of the Tec family, forms a complex with poly(ADP-ribose) polymerase 1 and elongation factor 1alpha and regulates interferon-gamma gene transcription in Th1 cells

XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage

Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death

In silico characterization of the family of PARP-like poly(ADP-ribosyl)transferases (pARTs)

A third zinc-binding domain of human poly(ADP-ribose) polymerase-1 coordinates DNA-dependent enzyme activation

Domain C of human poly(ADP-ribose) polymerase-1 is important for enzyme activity and contains a novel zinc-ribbon motif

Structure of the catalytic fragment of poly(AD-ribose) polymerase from chicken

Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1

Poly(ADP-ribose) polymerase null mouse cells synthesize ADP-ribose polymers

Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

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scholarly article

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10.1016/J.AJPATH.2010.12.004

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