Statin-induced mevalonate pathway inhibition attenuates the growth of mesenchymal-like cancer cells that lack functional E-cadherin mediated cell cohesion
about
Mathematical models of cancer metabolismDifferential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasionIdentification of CETP as a molecular target for estrogen positive breast cancer cell death by cholesterol depleting agentsQuantification of folate metabolism using transient metabolic flux analysis.Shared Risk Factors in Cardiovascular Disease and Cancer.Statin Use and Its Impact on Survival in Pancreatic Cancer PatientsAltered Mitochondrial Signalling and Metabolism in Cancer.Statin attenuates cell proliferative ability via TAZ (WWTR1) in hepatocellular carcinoma.The Role of Cholesterol in Cancer.Therapeutic Targeting of Epithelial Plasticity Programs: Focus on the Epithelial-Mesenchymal Transition.Targeting the Metabolic Reprogramming That Controls Epithelial-to-Mesenchymal Transition in Aggressive Tumors.Novel Indications for Commonly Used Medications as Radiation Protectants in Spaceflight.Simvastatin treatment boosts benefits of apoptotic cell infusion in murine lung fibrosisProteomic profiling of human plasma identifies apolipoprotein E as being associated with smoking and a marker for squamous metaplasia of the lung.Inflammatory Proteomic Network Analysis of Statin-treated and Lipopolysaccharide-activated Macrophages.The interplay between mutant p53 and the mevalonate pathway.Simvastatin Inhibits Cell Proliferation and Migration in Human Anaplastic Thyroid Cancer.Biomarker identification for statin sensitivity of cancer cell lines.Cilia loss sensitizes cells to transformation by activating the mevalonate pathway.Combined pitavastatin and dacarbazine treatment activates apoptosis and autophagy resulting in synergistic cytotoxicity in melanoma cells.Depletion of membrane cholesterol compromised caspase-8 imparts in autophagy induction and inhibition of cell migration in cancer cells.An image-based small-molecule screen identifies vimentin as a pharmacologically relevant target of simvastatin in cancer cells.Simvastatin Reduces Cancerogenic Potential of Renal Cancer Cells via Geranylgeranyl Pyrophosphate and Mevalonate Pathway.Lipophilic statins limit cancer cell growth and survival, via involvement of Akt signaling.Shift from stochastic to spatially-ordered expression of serine-glycine synthesis enzymes in 3D microtumors.Immune response to influenza vaccination in the elderly is altered by chronic medication useMevalonate Metabolism in Cancer Stemness and Trained Immunity
P2860
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P2860
Statin-induced mevalonate pathway inhibition attenuates the growth of mesenchymal-like cancer cells that lack functional E-cadherin mediated cell cohesion
description
2014 nî lūn-bûn
@nan
2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Statin-induced mevalonate path ...... adherin mediated cell cohesion
@ast
Statin-induced mevalonate path ...... adherin mediated cell cohesion
@en
Statin-induced mevalonate path ...... adherin mediated cell cohesion
@nl
type
label
Statin-induced mevalonate path ...... adherin mediated cell cohesion
@ast
Statin-induced mevalonate path ...... adherin mediated cell cohesion
@en
Statin-induced mevalonate path ...... adherin mediated cell cohesion
@nl
prefLabel
Statin-induced mevalonate path ...... adherin mediated cell cohesion
@ast
Statin-induced mevalonate path ...... adherin mediated cell cohesion
@en
Statin-induced mevalonate path ...... adherin mediated cell cohesion
@nl
P2093
P2860
P356
P1433
P1476
Statin-induced mevalonate path ...... adherin mediated cell cohesion
@en
P2093
Alexei Vazquez
Colin H Beckwitt
Katsuhiko Warita
Tomoko Warita
Zoltán N Oltvai
P2860
P2888
P356
10.1038/SREP07593
P407
P577
2014-12-23T00:00:00Z
P5875
P6179
1020983952