Design and synthesis of substituted N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamides as positive allosteric modulators of the metabotropic glutamate receptor subtype 5.
about
Drugs for allosteric sites on receptorsProgress toward positive allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5).Investigating metabotropic glutamate receptor 5 allosteric modulator cooperativity, affinity, and agonism: enriching structure-function studies and structure-activity relationships.Identification of specific ligand-receptor interactions that govern binding and cooperativity of diverse modulators to a common metabotropic glutamate receptor 5 allosteric site.Metabotropic glutamate receptor 5-positive allosteric modulators for the treatment of schizophrenia (2004-2012).Optimization of an ether series of mGlu5 positive allosteric modulators: molecular determinants of MPEP-site interaction crossover.Modification of Boc-Protected CAN508 via Acylation and Suzuki-Miyaura Coupling.
P2860
Q27006721-F9AD05FD-2F5A-4231-BC5A-AA880E17E6FCQ36015452-7E2D0391-C14C-4A77-A265-6D8B5F11E572Q36335613-38C1D8F8-3192-464B-8A60-EF8657610C7FQ37709393-08A9381D-B5BC-4C78-85DA-2C9BDDAF42ABQ38162957-8AD0A85F-445C-4D38-846F-50DCE66E9E28Q42573965-6FDCF8A5-1AE9-4505-B824-B79E8F1114BBQ48253446-7EF89BEA-C0C3-41EB-98F6-A94895D04CAC
P2860
Design and synthesis of substituted N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamides as positive allosteric modulators of the metabotropic glutamate receptor subtype 5.
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Design and synthesis of substi ...... glutamate receptor subtype 5.
@ast
Design and synthesis of substi ...... glutamate receptor subtype 5.
@en
Design and synthesis of substi ...... glutamate receptor subtype 5.
@nl
type
label
Design and synthesis of substi ...... glutamate receptor subtype 5.
@ast
Design and synthesis of substi ...... glutamate receptor subtype 5.
@en
Design and synthesis of substi ...... glutamate receptor subtype 5.
@nl
prefLabel
Design and synthesis of substi ...... glutamate receptor subtype 5.
@ast
Design and synthesis of substi ...... glutamate receptor subtype 5.
@en
Design and synthesis of substi ...... glutamate receptor subtype 5.
@nl
P2093
P2860
P1476
Design and synthesis of substi ...... glutamate receptor subtype 5.
@en
P2093
Alice L Rodriguez
Jianjing Cao
P2860
P304
P356
10.1016/J.BMCL.2010.12.110
P407
P577
2010-12-28T00:00:00Z