Molecular determinants and thermodynamics of the amyloid precursor protein transmembrane domain implicated in Alzheimer's disease.
about
Dimeric structure of transmembrane domain of amyloid precursor protein in micellar environmentFamilial Alzheimer’s mutations within APPTM increase Aβ42 production by enhancing accessibility of ε-cleavage siteStructural heterogeneity in transmembrane amyloid precursor protein homodimer is a consequence of environmental selection.Modulation of γ-secretase activity by multiple enzyme-substrate interactions: implications in pathogenesis of Alzheimer's diseaseAssessing the relative stability of dimer interfaces in g protein-coupled receptors.Independent relationship between amyloid precursor protein (APP) dimerization and γ-secretase processivity.Solution NMR approaches for establishing specificity of weak heterodimerization of membrane proteinsExtension of a protein docking algorithm to membranes and applications to amyloid precursor protein dimerization.Impact of membrane lipid composition on the structure and stability of the transmembrane domain of amyloid precursor protein.Cholesterol as a co-solvent and a ligand for membrane proteins.Impact of bilayer lipid composition on the structure and topology of the transmembrane amyloid precursor C99 proteinA transmembrane domain and GxxxG motifs within L2 are essential for papillomavirus infection.Dimerization of the transmembrane domain of amyloid precursor protein is determined by residues around the γ-secretase cleavage sites.The backbone dynamics of the amyloid precursor protein transmembrane helix provides a rationale for the sequential cleavage mechanism of γ-secretase.Competition between homodimerization and cholesterol binding to the C99 domain of the amyloid precursor protein.Screening for transmembrane association in divisome proteins using TOXGREEN, a high-throughput variant of the TOXCAT assayBackbone Hydrogen Bond Strengths Can Vary Widely in Transmembrane Helices.Coupled Transmembrane Substrate Docking and Helical Unwinding in Intramembrane Proteolysis of Amyloid Precursor Protein
P2860
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P2860
Molecular determinants and thermodynamics of the amyloid precursor protein transmembrane domain implicated in Alzheimer's disease.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Molecular determinants and the ...... icated in Alzheimer's disease.
@ast
Molecular determinants and the ...... icated in Alzheimer's disease.
@en
Molecular determinants and the ...... icated in Alzheimer's disease.
@nl
type
label
Molecular determinants and the ...... icated in Alzheimer's disease.
@ast
Molecular determinants and the ...... icated in Alzheimer's disease.
@en
Molecular determinants and the ...... icated in Alzheimer's disease.
@nl
prefLabel
Molecular determinants and the ...... icated in Alzheimer's disease.
@ast
Molecular determinants and the ...... icated in Alzheimer's disease.
@en
Molecular determinants and the ...... icated in Alzheimer's disease.
@nl
P2093
P2860
P1476
Molecular determinants and the ...... licated in Alzheimer's disease
@en
P2093
Celia Torres-Arancivia
Davide Provasi
Iban Ubarretxena-Belandia
Imane Djemil
P2860
P304
P356
10.1016/J.JMB.2011.03.028
P407
P577
2011-03-31T00:00:00Z