Loss of Acid sensing ion channel-1a and bicarbonate administration attenuate the severity of traumatic brain injury
about
Two aspects of ASIC function: Synaptic plasticity and neuronal injury.Selective inhibition of ASIC1a confers functional and morphological neuroprotection following traumatic spinal cord injury.Protons are a neurotransmitter that regulates synaptic plasticity in the lateral amygdala.Tissue acidosis induces neuronal necroptosis via ASIC1a channel independent of its ionic conduction.Proton-sensitive cation channels and ion exchangers in ischemic brain injury: new therapeutic targets for stroke?ASICs and neuropeptides.Acid-sensing ion channels regulate spontaneous inhibitory activity in the hippocampus: possible implications for epilepsy.Region specific contribution of ASIC2 to acidosis-and ischemia-induced neuronal injury.miR-149 reduces while let-7 elevates ASIC1a expression in vitro.Human ASIC1a mediates stronger acid-induced responses as compared with mouse ASIC1a.Acid-sensing ion channels: dual function proteins for chemo-sensing and mechano-sensing.Targeted Acid-Sensing Ion Channel Therapies for Migraine.
P2860
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P2860
Loss of Acid sensing ion channel-1a and bicarbonate administration attenuate the severity of traumatic brain injury
description
2013 nî lūn-bûn
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2013 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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Loss of Acid sensing ion chann ...... rity of traumatic brain injury
@ast
Loss of Acid sensing ion chann ...... rity of traumatic brain injury
@en
Loss of Acid sensing ion chann ...... rity of traumatic brain injury
@nl
type
label
Loss of Acid sensing ion chann ...... rity of traumatic brain injury
@ast
Loss of Acid sensing ion chann ...... rity of traumatic brain injury
@en
Loss of Acid sensing ion chann ...... rity of traumatic brain injury
@nl
prefLabel
Loss of Acid sensing ion chann ...... rity of traumatic brain injury
@ast
Loss of Acid sensing ion chann ...... rity of traumatic brain injury
@en
Loss of Acid sensing ion chann ...... rity of traumatic brain injury
@nl
P2093
P2860
P1433
P1476
Loss of Acid sensing ion chann ...... rity of traumatic brain injury
@en
P2093
Gregory W Albert
M Sean Grady
Michael J Welsh
Peter B Schmeiser
Raheel Ahmed
Timothy E Lindley
P2860
P304
P356
10.1371/JOURNAL.PONE.0072379
P407
P577
2013-08-26T00:00:00Z