about
Evaluation of NTHL1, NEIL1, NEIL2, MPG, TDG, UNG and SMUG1 genes in familial colorectal cancer predispositionFunctional significance of the conserved residues for the 23-residue module among MTH1 and MutT family proteinsCharacterization of a mammalian homolog of the Escherichia coli MutY mismatch repair proteinCloning and characterization of a functional human homolog of Escherichia coli endonuclease IIIA novel mechanism for preventing mutations caused by oxidation of guanine nucleotides.Spontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPaseEfficient and error-free replication past a minor-groove DNA adduct by the sequential action of human DNA polymerases iota and kappaCoordination of steps in single-nucleotide base excision repair mediated by apurinic/apyrimidinic endonuclease 1 and DNA polymerase betaMammalian enzymes for preventing transcriptional errors caused by oxidative damage.Kinetics of Mismatch Formation opposite Lesions by the Replicative DNA Polymerase from Bacteriophage RB69Mutagenic conformation of 8-oxo-7,8-dihydro-2′-dGTP in the confines of a DNA polymerase active siteStructures of dNTP Intermediate States during DNA Polymerase Active Site AssemblyDNA polymerase minor groove interactions modulate mutagenic bypass of a templating 8-oxoguanine lesionBinary complex crystal structure of DNA polymerase reveals multiple conformations of the templating 8-oxoguanine lesionOxidant and environmental toxicant-induced effects compromise DNA ligation during base excision DNA repairComplete rescue of lethal albino c14CoS mice by null mutation of 4-hydroxyphenylpyruvate dioxygenase and induction of apoptosis of hepatocytes in these mice by in vivo retrieval of the tyrosine catabolic pathwayA reliable assessment of 8-oxo-2-deoxyguanosine levels in nuclear and mitochondrial DNA using the sodium iodide method to isolate DNARegulation of expression of the human MTH1 gene encoding 8-oxo-dGTPase. Alternative splicing of transcription productsComprehensive analysis of the contribution of germline MYH variation to early-onset colorectal cancerDeciphering signatures of mutational processes operative in human cancerHealth-promoting components of fruits and vegetables in the dietThe pineal secretory product melatonin reduces hydrogen peroxide-induced DNA damage in U-937 cellsPossible role of lipid peroxidation in the induction of NF-kappa B and AP-1 in RFL-6 cells by crocidolite asbestos: evidence following protection by vitamin EFormation and persistence of 8-oxoguanine in rat lung cells as an important determinant for tumor formation following particle exposureIdentification of human MutY homolog (hMYH) as a repair enzyme for 2-hydroxyadenine in DNA and detection of multiple forms of hMYH located in nuclei and mitochondriaCancer risks for monoallelic MUTYH mutation carriers with a family history of colorectal cancer.DNA-XPA interactions: a (31)P NMR and molecular modeling study of dCCAATAACC association with the minimal DNA-binding domain (M98-F219) of the nucleotide excision repair protein XPA.Characterization of the recombinant MutY homolog, an adenine DNA glycosylase, from yeast Schizosaccharomyces pombe.Repair kinetics of trans-4-hydroxynonenal-induced cyclic 1,N2-propanodeoxyguanine DNA adducts by human cell nuclear extractsCalorie restriction and cancer prevention: metabolic and molecular mechanisms.MUTYH Mutations Do Not Cause HNPCC or Late Onset Familial Colorectal CancerSomatic mutations, genome mosaicism, cancer and aging.Poly(ADP-ribose) polymerase-1 inhibition: preclinical and clinical development of synthetic lethality.Capturing a mammalian DNA polymerase extending from an oxidized nucleotide.Antioxidative effects of melatonin in protection against cellular damage caused by ionizing radiation.Transformation of mammalian cells by overexpressing H2O2-generating peroxisomal fatty acyl-CoA oxidasePivotal role of inosine triphosphate pyrophosphatase in maintaining genome stability and the prevention of apoptosis in human cells.Erroneous incorporation of oxidized DNA precursors by Y-family DNA polymerasesEfficient recognition of substrates and substrate analogs by the adenine glycosylase MutY requires the C-terminal domain.Oxidative DNA damage induced by copper and hydrogen peroxide promotes CG-->TT tandem mutations at methylated CpG dinucleotides in nucleotide excision repair-deficient cells.
P2860
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P2860
description
1991 nî lūn-bûn
@nan
1991 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Endogenous mutagens and the causes of aging and cancer.
@ast
Endogenous mutagens and the causes of aging and cancer.
@en
Endogenous mutagens and the causes of aging and cancer.
@nl
type
label
Endogenous mutagens and the causes of aging and cancer.
@ast
Endogenous mutagens and the causes of aging and cancer.
@en
Endogenous mutagens and the causes of aging and cancer.
@nl
prefLabel
Endogenous mutagens and the causes of aging and cancer.
@ast
Endogenous mutagens and the causes of aging and cancer.
@en
Endogenous mutagens and the causes of aging and cancer.
@nl
P1433
P1476
Endogenous mutagens and the causes of aging and cancer.
@en
P356
10.1016/0027-5107(91)90157-J
P407
P577
1991-09-01T00:00:00Z