MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication - sprookjes - yvandenbroek - TriplyDB

MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication

MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication

http://www.wikidata.org/entity/Q34998668

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The RecQ DNA helicases in DNA repair Human RECQ helicases: roles in DNA metabolism, mutagenesis and cancer biology Genome-wide comprehensive analysis of human helicases How do Cdc7 and cyclin-dependent kinases trigger the initiation of chromosome replication in eukaryotic cells?The role of RecQ helicases in non-homologous end-joining RECQL4 in genomic instability and aging Solution NMR Structure of the C-terminal DNA Binding Domain of Mcm10 Reveals a Conserved MCM Motif Mcm10 Self-Association Is Mediated by an N-Terminal Coiled-Coil Domain The N-terminus of the human RecQL4 helicase is a homeodomain-like DNA interaction motif RecQ helicases in DNA double strand break repair and telomere maintenance.The replication initiation protein Sld2 regulates helicase assembly.Drosophila Mcm10 is required for DNA replication and differentiation in the compound eye RECQL4, the protein mutated in Rothmund-Thomson syndrome, functions in telomere maintenance RecQL4 is required for the association of Mcm10 and Ctf4 with replication origins in human cells Xenopus DNA2 is a helicase/nuclease that is found in complexes with replication proteins And-1/Ctf4 and Mcm10 and DSB response proteins Nbs1 and ATM The involvement of human RECQL4 in DNA double-strand break repair.Impaired p32 regulation caused by the lymphoma-prone RECQ4 mutation drives mitochondrial dysfunction.Human RECQ1 and RECQ4 helicases play distinct roles in DNA replication initiation The Rothmund-Thomson syndrome helicase RECQL4 is essential for hematopoiesis.Multiple functions for Drosophila Mcm10 suggested through analysis of two Mcm10 mutant alleles Drosophila RecQ4 is directly involved in both DNA replication and the response to UV damage in S2 cells.The intrinsically disordered amino-terminal region of human RecQL4: multiple DNA-binding domains confer annealing, strand exchange and G4 DNA binding.The helicase and ATPase activities of RECQL4 are compromised by mutations reported in three human patients RECQL4 Promotes DNA End Resection in Repair of DNA Double-Strand Breaks.Human RecQL4 helicase plays critical roles in prostate carcinogenesis.Over expression of minichromosome maintenance genes is clinically correlated to cervical carcinogenesis.RecQL4 helicase amplification is involved in human breast tumorigenesis.Human DNA helicase B interacts with the replication initiation protein Cdc45 and facilitates Cdc45 binding onto chromatin Borrowing nuclear DNA helicases to protect mitochondrial DNA."...Rewritten in the skin": clues to skin biology and aging from inherited disease.RECQL4 localizes to mitochondria and preserves mitochondrial DNA integrity Human RecQ helicases in DNA repair, recombination, and replication.The human RecQ helicases BLM and RECQL4 cooperate to preserve genome stability.The Expression and Prognostic Roles of MCMs in Pancreatic Cancer.RecQ4 promotes the conversion of the pre-initiation complex at a site-specific origin for DNA unwinding in Xenopus egg extracts DEC1 regulates breast cancer cell proliferation by stabilizing cyclin E protein and delays the progression of cell cycle S phase.Sequential posttranslational modifications program FEN1 degradation during cell-cycle progression Emerging players in the initiation of eukaryotic DNA replication.RECQ1 is required for cellular resistance to replication stress and catalyzes strand exchange on stalled replication fork structures.Interaction of RECQ4 and MCM10 is important for efficient DNA replication origin firing in human cells.

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MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication

http://www.wikidata.org/entity/Q34998668

description

2009 nî lūn-bûn

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2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2009年の論文

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2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication

@ast

MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication

@en

MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication

@nl

type

label

MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication

@ast

MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication

@en

MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication

@nl

prefLabel

MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication

@ast

MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication

@en

MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication

@nl

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The EMBO Journal

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MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication

@en

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Eminet A Feyissa

http://www.w3.org/2001/XMLSchema#string

Patrick J Rochette

http://www.w3.org/2001/XMLSchema#string

Tina V Su

http://www.w3.org/2001/XMLSchema#string

Xiaohua Xu

http://www.w3.org/2001/XMLSchema#string

Yilun Liu

http://www.w3.org/2001/XMLSchema#string

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CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair

Dual DNA unwinding activities of the Rothmund-Thomson syndrome protein, RECQ4

Roles of RECQ helicases in recombination based DNA repair, genomic stability and aging

More complexity to the Bloom's syndrome complex

A CDK-catalysed regulatory phosphorylation for formation of the DNA replication complex Sld2-Dpb11

Mcm10 and the MCM2-7 complex interact to initiate DNA synthesis and to release replication factors from origins.

CDK-dependent phosphorylation of Sld2 and Sld3 initiates DNA replication in budding yeast.

Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast.

Cyclin A in cell cycle control and cancer

S-Cdk-dependent phosphorylation of Sld2 essential for chromosomal DNA replication in budding yeast

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3005-3014

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10.1038/EMBOJ.2009.235

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19

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28

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2009-08-20T00:00:00Z

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26757194

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19696745

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2760112

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