PRMT5 is upregulated in malignant and metastatic melanoma and regulates expression of MITF and p27(Kip1.).
about
The PRMT5 arginine methyltransferase: many roles in development, cancer and beyondPRMT5 regulates IRES-dependent translation via methylation of hnRNP A1.MITF in melanoma: mechanisms behind its expression and activity.Methylosome Protein 50 and PKCδ/p38δ Protein Signaling Control Keratinocyte Proliferation via Opposing Effects on p21Cip1 Gene ExpressionArginine methyltransferase PRMT5 is essential for sustaining normal adult hematopoiesis.Myc and Omomyc functionally associate with the Protein Arginine Methyltransferase 5 (PRMT5) in glioblastoma cells.PRMT5 Is Upregulated in HTLV-1-Mediated T-Cell Transformation and Selective Inhibition Alters Viral Gene Expression and Infected Cell Survival.Multiparameter Evaluation of the Heterogeneity of Circulating Tumor Cells Using Integrated RNA In Situ Hybridization and Immunocytochemical Analysis.The protein arginine methyltransferase 5 promotes malignant phenotype of hepatocellular carcinoma cells and is associated with adverse patient outcomes after curative hepatectomyEZH2: an emerging role in melanoma biology and strategies for targeted therapy.Role of PRMTs in cancer: Could minor isoforms be leaving a mark?Targeting epigenetic regulators for cancer therapy: modulation of bromodomain proteins, methyltransferases, demethylases, and microRNAs.Elevated expression of protein arginine methyltransferase 5 predicts the poor prognosis of breast cancer.Inhibitors of Protein Methyltransferases and Demethylases.Discovery of selective protein arginine methyltransferase 5 inhibitors and biological evaluations.Histone Modifications and Cancer.Transcriptional activation of PRMT5 by NF-Y is required for cell growth and negatively regulated by the PKC/c-Fos signaling in prostate cancer cells.Late Cornified Envelope Group I, a novel target of p53, regulates PRMT5 activity.The dual epigenetic role of PRMT5 in acute myeloid leukemia: gene activation and repression via histone arginine methylation.High nuclear expression of protein arginine methyltransferase-5 is a potentially useful marker to estimate submucosal invasion in endoscopically resected early colorectal carcinoma.Proliferative role of TRAF4 in breast cancer by upregulating PRMT5 nuclear expression.SHARPIN-mediated regulation of protein arginine methyltransferase 5 controls melanoma growth.Sulforaphane suppresses PRMT5/MEP50 function in epidermal squamous cell carcinoma leading to reduced tumor formation.Expression of proteins involved in epigenetic regulation in human cutaneous melanoma and peritumoral skin.CAPG enhances breast cancer metastasis by competing with PRMT5 to modulate STC-1 transcription.
P2860
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P2860
PRMT5 is upregulated in malignant and metastatic melanoma and regulates expression of MITF and p27(Kip1.).
description
2013 nî lūn-bûn
@nan
2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
PRMT5 is upregulated in malign ...... ession of MITF and p27(Kip1.).
@ast
PRMT5 is upregulated in malign ...... ession of MITF and p27(Kip1.).
@en
type
label
PRMT5 is upregulated in malign ...... ession of MITF and p27(Kip1.).
@ast
PRMT5 is upregulated in malign ...... ession of MITF and p27(Kip1.).
@en
prefLabel
PRMT5 is upregulated in malign ...... ession of MITF and p27(Kip1.).
@ast
PRMT5 is upregulated in malign ...... ession of MITF and p27(Kip1.).
@en
P2093
P2860
P1433
P1476
PRMT5 is upregulated in malign ...... ession of MITF and p27(Kip1.).
@en
P2093
Eugenio Gaudio
Fengting Yan
Gregory B Lesinski
Gregory S Young
Jennifer Yang
Matthew A Bill
Michael R Grever
Robert A Baiocchi
Sara B Peters
Sookil Tae
P2860
P304
P356
10.1371/JOURNAL.PONE.0074710
P407
P577
2013-09-30T00:00:00Z