Role of common human TRIM5alpha variants in HIV-1 disease progression
about
TRIM family proteins and their emerging roles in innate immunityTRIM5alpha Modulates Immunodeficiency Virus Control in Rhesus MonkeysA rare null allele potentially encoding a dominant-negative TRIM5alpha protein in Baka pygmiesCyclophilins and nucleoporins are required for infection mediated by capsids from circulating HIV-2 primary isolates.TRIM5 alpha drives SIVsmm evolution in rhesus macaques.The effect of Trim5 polymorphisms on the clinical course of HIV-1 infection.Interpreting missense mutations in Human TRIM5alpha by computational methodsRubella vaccine-induced cellular immunity: evidence of associations with polymorphisms in the Toll-like, vitamin A and D receptors, and innate immune response genesTRIM5 suppresses cross-species transmission of a primate immunodeficiency virus and selects for emergence of resistant variants in the new speciesStabilized human TRIM5α protects human T cells from HIV-1 infection.High systemic levels of interleukin-10, interleukin-22 and C-reactive protein in Indian patients are associated with low in vitro replication of HIV-1 subtype C virusesHost genetics influences on HIV type-1 disease.Association of TRIM22 with the type 1 interferon response and viral control during primary HIV-1 infectionA rare missense variant abrogates the signaling activity of tetherin/BST-2 without affecting its effect on virus releaseTRIM5α restriction affects clinical outcome and disease progression in simian immunodeficiency virus-infected rhesus macaquesModulation of TRIM5alpha activity in human cells by alternatively spliced TRIM5 isoforms.Vaccinomics: current findings, challenges and novel approaches for vaccine developmentBalancing selection and the evolution of functional polymorphism in Old World monkey TRIM5alpha.Vaccinomics and a new paradigm for the development of preventive vaccines against viral infections.In silico analysis of functional single nucleotide polymorphisms in the human TRIM22 geneThe TRIM5 gene modulates penile mucosal acquisition of simian immunodeficiency virus in rhesus monkeys.APOBEC3G levels predict rates of progression to AIDSHost genes important to HIV replication and evolution.Host factors influencing susceptibility to HIV infection and AIDS progression.Genetic polymorphisms of Trim5a are associated with disease progression in acutely and chronically HIV-infected patients.Antiretroviral activity of ancestral TRIM5alpha.Host restriction factors in retroviral infection: promises in virus-host interaction.The control of viral infection by tripartite motif proteins and cyclophilin A.A naturally occurring single amino acid substitution in human TRIM5α linker region affects its anti-HIV type 1 activity and susceptibility to HIV type 1 infection.Special anniversary review: twenty-five years of human immunodeficiency virus research: successes and challenges.Pressure from TRIM5α contributes to control of HIV-1 replication by individuals expressing protective HLA-B alleles.Host genes associated with HIV/AIDS: advances in gene discoveryHost Factors and HIV-1 Replication: Clinical Evidence and Potential Therapeutic ApproachesPreviously Unidentified Single Nucleotide Polymorphisms in HIV/AIDS Cases Associate with Clinical Parameters and Disease Progression.TRIM5α and TRIM22 are differentially regulated according to HIV-1 infection phase and compartment.Recent insights into the mechanism and consequences of TRIM5α retroviral restriction.Gag cytotoxic T lymphocyte escape mutations can increase sensitivity of HIV-1 to human TRIM5alpha, linking intrinsic and acquired immunity.Variability in a dominant block to SIV early reverse transcription in rhesus monkey cells predicts in vivo viral replication and time to death.TRIM5 gene polymorphisms in HIV-1-infected patients and healthy controls from Northeastern Brazil.Strain-specific differences in the impact of human TRIM5alpha, different TRIM5alpha alleles, and the inhibition of capsid-cyclophilin A interactions on the infectivity of HIV-1.
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P2860
Role of common human TRIM5alpha variants in HIV-1 disease progression
description
2006 nî lūn-bûn
@nan
2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Role of common human TRIM5alpha variants in HIV-1 disease progression
@ast
Role of common human TRIM5alpha variants in HIV-1 disease progression
@en
type
label
Role of common human TRIM5alpha variants in HIV-1 disease progression
@ast
Role of common human TRIM5alpha variants in HIV-1 disease progression
@en
prefLabel
Role of common human TRIM5alpha variants in HIV-1 disease progression
@ast
Role of common human TRIM5alpha variants in HIV-1 disease progression
@en
P2093
P2860
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Role of common human TRIM5alpha variants in HIV-1 disease progression
@en
P2093
Amalio Telenti
Gabriela Bleiber
Millàn Ortiz
Raquel Martinez
Valérie Goldschmidt
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P2888
P356
10.1186/1742-4690-3-54
P577
2006-08-22T00:00:00Z
P5875
P6179
1020734083