PDGF-D improves drug delivery and efficacy via vascular normalization, but promotes lymphatic metastasis by activating CXCR4 in breast cancer.
about
Interaction between circulating cancer cells and platelets: clinical implicationVascular heterogeneity and targeting: the role of YKL-40 in glioblastoma vascularizationEmerging roles of PDGF-D in EMT progression during tumorigenesisPlatelet-derived growth factor receptor/platelet-derived growth factor (PDGFR/PDGF) system is a prognostic and treatment response biomarker with multifarious therapeutic targets in cancers.Normalization of the vasculature for treatment of cancer and other diseases.PDGF: the nuts and bolts of signalling toolbox.CXCL12 (SDF1alpha)-CXCR4/CXCR7 pathway inhibition: an emerging sensitizer for anticancer therapies?Angiostatic treatment prior to chemo- or photodynamic therapy improves anti-tumor efficacy.Integrins and their extracellular matrix ligands in lymphangiogenesis and lymph node metastasisAlcohol consumption suppresses mammary tumor metastasis in a syngeneic tumor transplantation modelFunctional malignant cell heterogeneity in pancreatic neuroendocrine tumors revealed by targeting of PDGF-DDKrüppel-like factor 8 activates the transcription of C-X-C cytokine receptor type 4 to promote breast cancer cell invasion, transendothelial migration and metastasis.Distinct roles of DKK1 and DKK2 in tumor angiogenesis.Differential tumorigenic potential and matriptase activation between PDGF B versus PDGF D in prostate cancer.Over-expression of platelet-derived growth factor-D promotes tumor growth and invasion in endometrial cancer.PDGF-D promotes cell growth, aggressiveness, angiogenesis and EMT transformation of colorectal cancer by activation of Notch1/Twist1 pathway.Aspirin inhibit platelet-induced epithelial-to-mesenchymal transition of circulating tumor cells (Review).The impact of tumor microenvironment on cancer treatment and its modulation by direct and indirect antivascular strategies.Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapyOncogenic miR-20a and miR-106a enhance the invasiveness of human glioma stem cells by directly targeting TIMP-2.Cell surface nucleolin is crucial in the activation of the CXCL12/CXCR4 signaling pathway.Growth factor receptor-Src-mediated suppression of GRK6 dysregulates CXCR4 signaling and promotes medulloblastoma migration.Platelet-derived growth factor receptor-α promotes lymphatic metastases in papillary thyroid cancer.Tumor angiogenesis and vascular normalization: alternative therapeutic targets.Tumor-derived mural-like cells coordinate with endothelial cells: role of YKL-40 in mural cell-mediated angiogenesisPD-L1 blockade enhances response of pancreatic ductal adenocarcinoma to radiotherapy.Vascular normalization in cerebral angiogenesis: friend or foe?Platelet-derived growth factors induced lymphangiogenesis: evidence, unanswered questions and upcoming challenges.Enhanced metastatic capacity of breast cancer cells after interaction and hybrid formation with mesenchymal stroma/stem cells (MSC).Platelet-derived growth factor-D promotes colorectal cancer cell migration, invasion and proliferation by regulating Notch1 and matrix metalloproteinase-9.IL6 derived from cancer-associated fibroblasts promotes chemoresistance via CXCR7 in esophageal squamous cell carcinoma.Transport of drugs from blood vessels to tumour tissue.
P2860
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P2860
PDGF-D improves drug delivery and efficacy via vascular normalization, but promotes lymphatic metastasis by activating CXCR4 in breast cancer.
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
PDGF-D improves drug delivery ...... vating CXCR4 in breast cancer.
@ast
PDGF-D improves drug delivery ...... vating CXCR4 in breast cancer.
@en
type
label
PDGF-D improves drug delivery ...... vating CXCR4 in breast cancer.
@ast
PDGF-D improves drug delivery ...... vating CXCR4 in breast cancer.
@en
prefLabel
PDGF-D improves drug delivery ...... vating CXCR4 in breast cancer.
@ast
PDGF-D improves drug delivery ...... vating CXCR4 in breast cancer.
@en
P2093
P2860
P1476
PDGF-D improves drug delivery ...... ivating CXCR4 in breast cancer
@en
P2093
Dai Fukumura
Jieqiong Liu
Peigen Huang
Rakesh K Jain
Rekha Samuel
Walid Kamoun
Yuhui Huang
P2860
P304
P356
10.1158/1078-0432.CCR-10-2456
P407
P577
2011-04-01T00:00:00Z